{
  "id": 4255,
  "label": "neuroendocrine carcinoma",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0002120",
  "properties": {
    "xrefs": [
      "DOID:1800",
      "GARD:0023067",
      "ICDO:8246/3",
      "MEDGEN:104919",
      "MESH:D018278",
      "NCIT:C3773",
      "SCTID:253000007",
      "UMLS:C0206695"
    ],
    "synonyms": [
      "NEC",
      "neuroendocrine cancer",
      "neuroendocrine carcinoma"
    ],
    "categories": [
      {
        "ref": "MONDO:0005151",
        "name": "endocrine system disorder"
      }
    ],
    "definition": "A malignant neuroendocrine neoplasm composed of cells containing secretory granules that stain positive for NSE and chromogranin. The neoplastic cells are often round and form clusters or trabecular sheets. Representative examples are small cell carcinoma, large cell neuroendocrine carcinoma, and Merkel cell carcinoma."
  },
  "isLeaf": false,
  "isRoot": false,
  "child_count": 12,
  "parents": [
    {
      "id": 6734,
      "label": "carcinoma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6733,
        7265
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "CSP:2000-1867",
          "DOID:305",
          "EFO:0000313",
          "ICDO:8010/3",
          "ICDO:8011/3",
          "MEDGEN:2867",
          "MESH:D002277",
          "NCIT:C2916",
          "SCTID:722688002",
          "UMLS:C0007097"
        ],
        "synonyms": [
          "epithelioma",
          "Other carcinoma",
          "carcinoma",
          "carcinoma, malignant",
          "epithelial carcinoma",
          "epithelioma malignant",
          "malignant epithelial neoplasm",
          "malignant epithelial tumor",
          "malignant epithelial tumour",
          "malignant epithelioma"
        ],
        "definition": "A malignant tumor arising from epithelial cells. Carcinomas that arise from glandular epithelium are called adenocarcinomas, those that arise from squamous epithelium are called squamous cell carcinomas, and those that arise from transitional epithelium are called transitional cell carcinomas. Morphologically, the malignant epithelial cells may display abnormal mitotic figures, anaplasia, and necrosis. Carcinomas are graded by the degree of cellular differentiation as well, moderately, or poorly differentiated. Carcinomas invade the surrounding tissues and tend to metastasize to other anatomic sites. Lung carcinoma, skin carcinoma, breast carcinoma, colon carcinoma, and prostate carcinoma are the most frequently seen carcinomas."
      },
      "child_count": 98,
      "reference_id": "MONDO:0004993"
    },
    {
      "id": 19314,
      "label": "neuroendocrine neoplasm",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        4223
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:169",
          "EFO:1001901",
          "GARD:0009316",
          "ICD9:209",
          "ICD9:209-209",
          "ICD9:239.7",
          "MEDGEN:64652",
          "MESH:D018358",
          "NCIT:C188218",
          "NCIT:C3809",
          "Orphanet:877",
          "SCTID:255046005",
          "UMLS:C0206754"
        ],
        "synonyms": [
          "APUDoma",
          "neuroendocrine neoplasm",
          "neuroendocrine tumor",
          "neuroendocrine tumour"
        ],
        "categories": [
          {
            "ref": "MONDO:0005151",
            "name": "endocrine system disorder"
          }
        ],
        "definition": "Endocrine tumors, also referred to as neuroendocrine tumors (NETs), are defined by a common phenotype which is characterized by the expression of general markers (neuron specific enolase, chromogranin, synaptophysin) and hormone secretion products. These tumors may be localized in any part of the body and are generally discovered in non-specific situations, i.e. not immediately suggestive of NETs (tests for inherited predisposition to tumors or for a clinical syndrome caused by abnormal hormone secretion)."
      },
      "child_count": 14,
      "reference_id": "MONDO:0019496"
    },
    {
      "id": 20310,
      "label": "malignant endocrine neoplasm",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        4223,
        6733
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:170",
          "ICD9:194.9",
          "MEDGEN:56319",
          "MESH:D004701",
          "NCIT:C3575",
          "UMLS:C0153658"
        ],
        "synonyms": [
          "endocrine neoplasm",
          "Endocrine tumour",
          "cancer of endocrine gland",
          "endocrine cancer",
          "endocrine gland cancer",
          "endocrine neoplasm, malignant",
          "malignant endocrine gland neoplasm",
          "malignant endocrine gland tumor",
          "malignant endocrine gland tumour",
          "malignant endocrine neoplasm",
          "malignant endocrine tumor",
          "malignant endocrine tumour",
          "malignant neoplasm of endocrine gland",
          "malignant neoplasm of the endocrine gland",
          "malignant tumor of endocrine gland",
          "malignant tumor of the endocrine gland",
          "malignant tumour of the endocrine gland"
        ],
        "categories": [
          {
            "ref": "MONDO:0005151",
            "name": "endocrine system disorder"
          }
        ],
        "definition": "A malignant neoplasm affecting the endocrine glands. Representative examples include thyroid gland carcinoma, parathyroid gland carcinoma, pituitary gland carcinoma, and adrenal cortex carcinoma."
      },
      "child_count": 32,
      "reference_id": "MONDO:0021069"
    }
  ],
  "children": [
    {
      "id": 2894,
      "label": "small cell carcinoma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        4255
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0050685",
          "EFO:0008524",
          "GARD:0022765",
          "ICDO:8041/3",
          "ICDO:8042/3",
          "MEDGEN:90748",
          "MESH:D018288",
          "NCIT:C3915",
          "NCIT:C4099",
          "SCTID:11010461000119101",
          "UMLS:C0334239"
        ],
        "synonyms": [
          "oat cell cancer",
          "oat cell carcinoma",
          "small cell NEC",
          "small cell cancer",
          "small cell car. (extrapulmonary)",
          "small cell carcinoma",
          "small cell carcinoma (extrapulmonary)",
          "small cell neuroendocrine carcinoma",
          "intermediate cell small cell carcinoma",
          "small cell carcinoma - intermediate cell",
          "small cell carcinoma, intermediate cell",
          "small cell carcinoma, intermediate cell (morphologic abnormality)"
        ],
        "categories": [
          {
            "ref": "MONDO:0005151",
            "name": "endocrine system disorder"
          }
        ],
        "definition": "A neuroendocrine carcinoma composed of small malignant cells which are often said to resemble \"oat cells\" under the microscope. Small cell carcinoma most often affects the lungs. Clinically, this is often a rapidly growing cancer that spreads to distant sites early."
      },
      "child_count": 18,
      "reference_id": "MONDO:0000402"
    },
    {
      "id": 5418,
      "label": "anal canal neuroendocrine neoplasm",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        4255,
        5534,
        8521
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:5545",
          "GARD:0023533",
          "MEDGEN:231063",
          "NCIT:C5603",
          "SCTID:717917007",
          "UMLS:C1332273"
        ],
        "synonyms": [
          "anal canal neuroendocrine neoplasm",
          "anal neuroendocrine neoplasm",
          "anus neuroendocrine neoplasm",
          "neuroendocrine neoplasm of anal canal",
          "neuroendocrine neoplasm of anus",
          "neuroendocrine neoplasm of the anus",
          "anal canal NET",
          "anal canal neuroendocrine tumor",
          "anal canal neuroendocrine tumor, well differentiated, low or intermediate grade",
          "anal canal neuroendocrine tumour",
          "anal neuroendocrine tumor",
          "anal neuroendocrine tumour",
          "anus neuroendocrine tumor",
          "anus neuroendocrine tumour",
          "neuroendocrine tumor of anus",
          "neuroendocrine tumour of anus"
        ],
        "categories": [
          {
            "ref": "MONDO:0004335",
            "name": "digestive system disorder"
          },
          {
            "ref": "MONDO:0005151",
            "name": "endocrine system disorder"
          }
        ],
        "definition": "A neoplasm with neuroendocrine differentiation that arises from the anal canal. It includes well differentiated neuroendocrine tumors (low and intermediate grade) and poorly differentiated neuroendocrine carcinomas (high grade)."
      },
      "child_count": 3,
      "reference_id": "MONDO:0003504"
    },
    {
      "id": 6787,
      "label": "large cell neuroendocrine carcinoma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        4255,
        6943
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0050872",
          "EFO:0000563",
          "GARD:0024145",
          "ICDO:8013/3",
          "MEDGEN:220402",
          "NCIT:C6875",
          "ONCOTREE:LUNE",
          "UMLS:C1265996",
          "icd11.foundation:1278312485"
        ],
        "synonyms": [
          "LCNEC",
          "large cell NEC",
          "large cell neuroendocrine carcinoma",
          "large-cell neuroendocrine carcinoma"
        ],
        "categories": [
          {
            "ref": "MONDO:0005151",
            "name": "endocrine system disorder"
          }
        ],
        "definition": "A usually aggressive carcinoma composed of large malignant cells which display neuroendocrine characteristics. It is characterized by the presence of high mitotic activity and necrotic changes. The vast majority of cases are positive for neuron-specific enolase. Representative examples include lung, breast, cervical, and thymic neuroendocrine carcinomas."
      },
      "child_count": 12,
      "reference_id": "MONDO:0005057"
    },
    {
      "id": 7497,
      "label": "pancreatic endocrine carcinoma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        4255,
        7431,
        7738,
        11035
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:1798",
          "EFO:0007416",
          "GARD:0022056",
          "ICD10CM:C25.4",
          "ICD9:157.4",
          "ICDO:8150/3",
          "MEDGEN:233070",
          "MESH:D018273",
          "NCIT:C3770",
          "Orphanet:506098",
          "SCTID:254612002",
          "UMLS:C1328479"
        ],
        "synonyms": [
          "Pancreatic Neuroendocrine cancer",
          "carcinoma of endocrine pancreas",
          "carcinoma, islet cell, malignant",
          "endocrine pancreas carcinoma",
          "high grade pancreatic neuroendocrine carcinoma",
          "high-grade pancreatic neuroendocrine carcinoma",
          "islet cell cancer",
          "islet cell carcinoma",
          "islet cell carcinoma (morphologic abnormality)",
          "malignant islet cell tumor",
          "malignant islet cell tumour",
          "malignant neoplasm of islets of Langerhans",
          "malignant pancreatic endocrine tumor",
          "malignant pancreatic endocrine tumour",
          "pancreatic NEC",
          "pancreatic NEC G3",
          "pancreatic endocrine cancer",
          "pancreatic endocrine carcinoma",
          "pancreatic neuroendocrine carcinoma",
          "poorly differentiated pancreatic endocrine carcinoma",
          "poorly-differentiated NEN of pancreas",
          "poorly-differentiated neuroendocrine neoplasm of pancreas",
          "poorly-differentiated pancreatic NEN",
          "poorly-differentiated pancreatic neuroendocrine neoplasm",
          "neuroendocrine carcinoma of pancreas"
        ],
        "categories": [
          {
            "ref": "MONDO:0004335",
            "name": "digestive system disorder"
          },
          {
            "ref": "MONDO:0005151",
            "name": "endocrine system disorder"
          }
        ],
        "definition": "An aggressive, high-grade and poorly differentiated carcinoma with neuroendocrine differentiation that arises from the pancreas. The mitotic count is more than 20 per 10 HPF. According to the size of the malignant cells, the prominence of the nucleoli, and the amount of cytoplasm, it is classified either as small or large cell neuroendocrine carcinoma."
      },
      "child_count": 8,
      "reference_id": "MONDO:0005893"
    },
    {
      "id": 7728,
      "label": "combined lung carcinoma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        4255,
        6862,
        7117,
        7464
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "EFO:1000200",
          "GARD:0024316",
          "MEDGEN:234166",
          "NCIT:C7591",
          "UMLS:C1333123"
        ],
        "synonyms": [
          "combined carcinoma of lung",
          "combined carcinoma of the lung",
          "combined lung cancer",
          "combined lung carcinoma"
        ],
        "categories": [
          {
            "ref": "MONDO:0005087",
            "name": "respiratory system disorder"
          },
          {
            "ref": "MONDO:0005151",
            "name": "endocrine system disorder"
          }
        ],
        "definition": "A lung carcinoma characterized by the presence of large or small neuroendocrine carcinoma cells in combination with malignant glandular or squamous epithelial cells."
      },
      "child_count": 8,
      "reference_id": "MONDO:0006167"
    },
    {
      "id": 7831,
      "label": "malignant adrenal gland pheochromocytoma",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        4255,
        4753,
        6024,
        6716,
        20329
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0080347",
          "EFO:1000348",
          "GARD:0024362",
          "ICDO:8700/3",
          "MEDGEN:87238",
          "NCIT:C4220",
          "SCTID:21851000119103",
          "UMLS:C0334419"
        ],
        "synonyms": [
          "adrenal gland pheochromocytoma, malignant",
          "malignant adrenal gland Chromaffinoma",
          "malignant adrenal gland chromaffin neoplasm",
          "malignant adrenal gland chromaffin paraganglioma",
          "malignant adrenal gland chromaffin tumor",
          "malignant adrenal gland chromaffin tumour",
          "malignant adrenal gland paraganglioma",
          "malignant adrenal gland pheochromocytoma",
          "malignant adrenal medullary paraganglioma",
          "malignant adrenal medullary pheochromocytoma",
          "malignant adrenal pheochromocytoma",
          "malignant pheochromocytoma",
          "pheochromoblastoma",
          "pheochromocytoma, malignant"
        ],
        "categories": [
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          },
          {
            "ref": "MONDO:0005151",
            "name": "endocrine system disorder"
          }
        ],
        "definition": "A pheochromocytoma that metastasizes to other anatomic sites. Common sites of metastasis include lymph nodes, bones, liver, and lung. Morphologic features associated with malignant pheochromocytomas include: atypical mitotic figures, capsular and vascular invasion, tumor cell necrosis, and high mitotic activity."
      },
      "child_count": 0,
      "reference_id": "MONDO:0006288"
    },
    {
      "id": 16046,
      "label": "liver neuroendocrine carcinoma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        4255,
        18551,
        21456
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0019760",
          "MEDGEN:474664",
          "NCIT:C96787",
          "Orphanet:100085",
          "SCTID:716652006",
          "UMLS:C3273031"
        ],
        "synonyms": [
          "HNEC",
          "PHNEC",
          "hepatic neuroendocrine carcinoma",
          "liver neuroendocrine cancer",
          "liver neuroendocrine carcinoma",
          "neuroendocrine carcinoma of liver",
          "primary hepatic neuroendocrine carcinoma",
          "primary liver neuroendocrine carcinoma"
        ],
        "categories": [
          {
            "ref": "MONDO:0004335",
            "name": "digestive system disorder"
          },
          {
            "ref": "MONDO:0005151",
            "name": "endocrine system disorder"
          }
        ],
        "definition": "An extremely rare, aggressive, high-grade and poorly differentiated carcinoma with neuroendocrine differentiation that arises from the liver."
      },
      "child_count": 6,
      "reference_id": "MONDO:0015072"
    },
    {
      "id": 16159,
      "label": "medullary thyroid gland carcinoma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        4255,
        6768
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:3973",
          "GARD:0007004",
          "HP:0002865",
          "MEDGEN:66772",
          "MedDRA:10027101",
          "NANDO:2201054",
          "NCIT:C3879",
          "ONCOTREE:THME",
          "Orphanet:1332",
          "SCTID:255032005",
          "UMLS:C0238462",
          "icd11.foundation:578519098"
        ],
        "synonyms": [
          "C cell carcinoma",
          "MTC",
          "carcinoma of parafollicular cell",
          "carcinoma, C-cell, malignant",
          "medullary carcinoma",
          "medullary carcinoma of the thyroid",
          "medullary carcinoma of the thyroid gland",
          "medullary carcinoma of thyroid",
          "medullary carcinoma of thyroid gland",
          "medullary thyroid cancer",
          "medullary thyroid carcinoma",
          "medullary thyroid gland carcinoma",
          "parafollicular cell carcinoma",
          "thyroid gland medullary cancer",
          "thyroid gland medullary carcinoma",
          "thyroid gland neuroendocrine carcinoma",
          "thyroid medullary carcinoma",
          "THME",
          "medullary thyroid cancer (MTC)",
          "thyroid cancer, medullary",
          "thyroid carcinoma, medullary"
        ],
        "categories": [
          {
            "ref": "MONDO:0005151",
            "name": "endocrine system disorder"
          }
        ],
        "definition": "A neuroendocrine carcinoma arising from the C-cells of the thyroid gland. It is closely associated with multiple endocrine neoplasia syndromes. Approximately 10% to 20% of medullary thyroid carcinomas are familial. Patients usually present with a thyroid nodule that is painless and firm. In the majority of cases nodal involvement is present at diagnosis. Surgery is the preferred treatment for both primary lesions and recurrences. This carcinoma is generally not very sensitive to radiation and almost unresponsive to chemotherapy."
      },
      "child_count": 2,
      "reference_id": "MONDO:0015277"
    },
    {
      "id": 18191,
      "label": "goblet cell carcinoma",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        4255,
        5155,
        16040,
        20711
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0010414",
          "ICDO:8243/3",
          "MEDGEN:60007",
          "NCIT:C3689",
          "NORD:1931",
          "ONCOTREE:GCCAP",
          "Orphanet:329984",
          "UMLS:C0205695"
        ],
        "synonyms": [
          "GCC",
          "Goblet Cell Adenocarcinoma",
          "appendix adenocarcinoid tumor",
          "appendix adenocarcinoid tumour",
          "appendix goblet cell carcinoid",
          "appendix goblet cell carcinoid tumor",
          "appendix goblet cell carcinoid tumour",
          "appendix mixed carcinoid-adenocarcinoma",
          "carcinoma of goblet cell",
          "goblet cell adenocarcinoid",
          "goblet cell carcinoid",
          "goblet cell carcinoid of appendix",
          "goblet cell carcinoid of the appendix",
          "goblet cell carcinoid tumor",
          "goblet cell carcinoid tumour",
          "goblet cell carcinoma",
          "goblet cell tumor",
          "goblet cell tumour",
          "mucinous carcinoid tumor",
          "mucinous carcinoid tumour",
          "mucinous carcinoid"
        ],
        "categories": [
          {
            "ref": "MONDO:0004335",
            "name": "digestive system disorder"
          },
          {
            "ref": "MONDO:0005151",
            "name": "endocrine system disorder"
          }
        ],
        "definition": "An aggressive type of endocrine tumor of the appendix presenting equally in males and females in the fifth decade of life and manifesting with a palpable mass and abdominal pain or acute appendicitis. Metastasis to the ovaries, peritoneum or right colon has usually already occurred in half of patients at the time of diagnosis."
      },
      "child_count": 0,
      "reference_id": "MONDO:0018017"
    },
    {
      "id": 19079,
      "label": "cutaneous neuroendocrine carcinoma",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        4255,
        4707,
        5298,
        7479,
        17658,
        20691
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0009266",
          "ICD10CM:C4A",
          "ICD9:209.36",
          "ICDO:8247/3",
          "MEDGEN:2843",
          "MESH:D015266",
          "NCIT:C9231",
          "NORD:1947",
          "ONCOTREE:MCC",
          "Orphanet:79140",
          "SCTID:253001006",
          "UMLS:C0007129",
          "icd11.foundation:680322043"
        ],
        "synonyms": [
          "MCC",
          "Merkel Cell Carcinoma",
          "Merkel cell cancer",
          "Merkel cell carcinoma",
          "Merkel cell tumor",
          "Merkel cell tumour",
          "carcinoma of Merkel cell",
          "cutaneous APUDoma",
          "cutaneous neuroendocrine carcinoma",
          "neuroendocrine carcinoma of skin",
          "neuroendocrine carcinoma of the skin",
          "neuroendocrine skin carcinoma",
          "trabecular cancer",
          "trabecular skin carcinoma",
          "Merkle tumors",
          "Merkle tumours",
          "carcinoma, Merkel cell"
        ],
        "categories": [
          {
            "ref": "MONDO:0002051",
            "name": "integumentary system disorder"
          },
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          },
          {
            "ref": "MONDO:0005151",
            "name": "endocrine system disorder"
          }
        ],
        "definition": "Cutaneous neuroendocrine carcinoma is a primary cutaneous cancer arising from a subset of skin neuroendocrine cells (Merkel cells, giving the name Merkel cell carcinoma (MCC))."
      },
      "child_count": 0,
      "reference_id": "MONDO:0019210"
    },
    {
      "id": 19965,
      "label": "thymic neuroendocrine carcinoma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        4255,
        7956,
        19679
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0019696",
          "MEDGEN:900590",
          "NCIT:C171031",
          "Orphanet:99869",
          "SCTID:716653001",
          "UMLS:C2210965",
          "icd11.foundation:381956131"
        ],
        "synonyms": [
          "neuroendocrine carcinoma of thymus",
          "thymic neuroendocrine carcinoma",
          "thymus neuroendocrine carcinoma"
        ],
        "categories": [
          {
            "ref": "MONDO:0005046",
            "name": "immune system disorder"
          },
          {
            "ref": "MONDO:0005151",
            "name": "endocrine system disorder"
          },
          {
            "ref": "MONDO:0005570",
            "name": "hematologic disorder"
          }
        ],
        "definition": "Thymic neuroendocrine carcinoma is a type of thymic epithelial neoplasm displaying evidence of neuroendocrine differentiation."
      },
      "child_count": 15,
      "reference_id": "MONDO:0020516"
    },
    {
      "id": 23671,
      "label": "vulvar neuroendocrine carcinoma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        4255,
        6931
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0025992",
          "MEDGEN:925534",
          "NCIT:C128243",
          "UMLS:C4288002"
        ],
        "synonyms": [
          "mammalian vulva neuroendocrine carcinoma",
          "neuroendocrine carcinoma of mammalian vulva",
          "vulvar Neuroendocrine cancer",
          "vulvar Neuroendocrine carcinoma",
          "vulvar high grade Neuroendocrine carcinoma",
          "vulvar high grade Neuroendocrine neoplasm"
        ],
        "categories": [
          {
            "ref": "MONDO:0005039",
            "name": "reproductive system disorder"
          },
          {
            "ref": "MONDO:0005151",
            "name": "endocrine system disorder"
          }
        ],
        "definition": "A neuroendocrine carcinoma that arises from the vulva. This category includes small cell and large cell neuroendocrine carcinoma. Most small cell neuroendocrine carcinomas of the vulva are Merkel cell carcinomas."
      },
      "child_count": 2,
      "reference_id": "MONDO:0056816"
    }
  ],
  "roots": [
    {
      "id": 6734,
      "label": "carcinoma"
    },
    {
      "id": 19314,
      "label": "neuroendocrine neoplasm"
    },
    {
      "id": 20310,
      "label": "malignant endocrine neoplasm"
    }
  ]
}