{
  "id": 4276,
  "label": "vaginal yolk sac tumor",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0002143",
  "properties": {
    "xrefs": [
      "DOID:1910",
      "GARD:0023076",
      "MEDGEN:234985",
      "NCIT:C6379",
      "ONCOTREE:VYST",
      "UMLS:C1336945"
    ],
    "synonyms": [
      "vaginal endodermal sinus neoplasm",
      "vaginal endodermal sinus tumor",
      "vaginal endodermal sinus tumour",
      "vaginal yolk Sac neoplasm",
      "vaginal yolk Sac tumor",
      "vaginal yolk Sac tumour",
      "yolk sac tumor",
      "yolk sac tumour"
    ],
    "categories": [
      {
        "ref": "MONDO:0005039",
        "name": "reproductive system disorder"
      }
    ],
    "definition": "A rare yolk sac tumor that arises from the vagina. Patients present with abnormal vaginal bleeding or bloody discharge."
  },
  "isLeaf": true,
  "isRoot": false,
  "child_count": 0,
  "parents": [
    {
      "id": 7365,
      "label": "yolk sac tumor",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        5475
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:1911",
          "EFO:0007252",
          "GARD:0000348",
          "ICDO:9071/3",
          "MEDGEN:41782",
          "MedDRA:10048251",
          "NANDO:2200069",
          "NCIT:C3011",
          "ONCOTREE:BYST",
          "Orphanet:876",
          "SCTID:404081005",
          "UMLS:C0014145"
        ],
        "synonyms": [
          "endodermal sinus neoplasm",
          "endodermal sinus tumor",
          "hepatoid yolk sac tumor",
          "yolk SAC tumor, malignant",
          "yolk Sac neoplasm",
          "yolk Sac tumor",
          "yolk Sac tumor site unspecified",
          "yolk Sac tumour site unspecified",
          "yolk sac tumor",
          "infantile embryonal carcinoma"
        ],
        "definition": "A non-seminomatous malignant germ cell tumor composed of primitive germ cells. It is the most common malignant germ cell tumor in the pediatric population. It occurs in the infant testis, ovary, sacrococcygeal region, vagina, uterus, prostate, abdomen, liver, retroperitoneum, thorax, and pineal/third ventricle. The tumor mimics the yolk sac of the embryo and produces alpha-fetoprotein (AFP). Treatment includes: surgical resection, radiation, and chemotherapy. This tumor is very responsive to chemotherapy regimens that include cisplatinum."
      },
      "child_count": 7,
      "reference_id": "MONDO:0005744"
    },
    {
      "id": 16721,
      "label": "vaginal germ cell malignant tumor",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        3623,
        7832
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0020347",
          "MEDGEN:1670250",
          "Orphanet:206489",
          "UMLS:C4749402"
        ],
        "synonyms": [
          "vagina malignant germ cell tumor",
          "vagina malignant germ cell tumour",
          "vaginal germ cell cancer",
          "malignant germ cell tumor of the vagina",
          "malignant germ cell tumour of the vagina"
        ],
        "categories": [
          {
            "ref": "MONDO:0005039",
            "name": "reproductive system disorder"
          }
        ],
        "definition": "A malignant germ cell tumor that involves the vagina."
      },
      "child_count": 2,
      "reference_id": "MONDO:0016094"
    }
  ],
  "children": [],
  "roots": [
    {
      "id": 7365,
      "label": "yolk sac tumor"
    },
    {
      "id": 16721,
      "label": "vaginal germ cell malignant tumor"
    }
  ]
}