{
  "id": 4336,
  "label": "central nervous system sarcoma",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0002217",
  "properties": {
    "xrefs": [
      "DOID:2133",
      "GARD:0023088",
      "MEDGEN:272444",
      "NCIT:C5153",
      "UMLS:C1332892"
    ],
    "synonyms": [
      "CNS sarcoma",
      "central nervous system sarcoma",
      "sarcoma of CNS",
      "sarcoma of central nervous system",
      "sarcoma of the CNS",
      "sarcoma of the central nervous system"
    ],
    "categories": [
      {
        "ref": "MONDO:0005071",
        "name": "nervous system disorder"
      }
    ],
    "definition": "A sarcoma that arises from the central nervous system."
  },
  "isLeaf": false,
  "isRoot": false,
  "child_count": 12,
  "parents": [
    {
      "id": 4753,
      "label": "central nervous system cancer",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        7479,
        7694
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:3620",
          "EFO:0000326",
          "GARD:0027614",
          "ICD9:239.7",
          "MEDGEN:87593",
          "MESH:D016543",
          "NANDO:2100007",
          "NCIT:C4627",
          "SCTID:126951006",
          "UMLS:C0348374"
        ],
        "synonyms": [
          "CNS neoplasm",
          "central nervous system tumor",
          "central nervous system tumour",
          "CNS cancer",
          "CNS malignant neoplasms",
          "CNS neoplasms, malignant",
          "cancer of CNS",
          "cancer of central nervous system",
          "cancer of the CNS",
          "cancer of the central nervous system",
          "central nervous system cancer",
          "central nervous system neoplasms, malignant",
          "central nervous system tumours",
          "malignant CNS neoplasm",
          "malignant CNS neoplasms",
          "malignant CNS tumor",
          "malignant CNS tumour",
          "malignant central nervous system neoplasm",
          "malignant central nervous system tumor",
          "malignant central nervous system tumour",
          "malignant neoplasm of CNS",
          "malignant neoplasm of central nervous system",
          "malignant neoplasm of the CNS",
          "malignant neoplasm of the central nervous system",
          "malignant tumor of CNS",
          "malignant tumor of central nervous system",
          "malignant tumor of the CNS",
          "malignant tumor of the central nervous system",
          "malignant tumour of CNS",
          "malignant tumour of central nervous system",
          "malignant tumour of the CNS",
          "malignant tumour of the central nervous system"
        ],
        "categories": [
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "A malignant neoplasm involving the central nervous system"
      },
      "child_count": 40,
      "reference_id": "MONDO:0002714"
    },
    {
      "id": 18239,
      "label": "soft tissue sarcoma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6816,
        21548
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0070663",
          "EFO:1001968",
          "GARD:0004898",
          "MEDGEN:1642116",
          "NCIT:C9306",
          "NORD:1953",
          "Orphanet:3394",
          "SCTID:424952003",
          "UMLS:C4551687"
        ],
        "synonyms": [
          "malignant soft tissue tumor",
          "malignant soft tissue tumour",
          "connective tissue sarcoma",
          "malignant mesenchymal tumor",
          "malignant mesenchymal tumour",
          "non-Rhabdo. soft tissue sarcoma",
          "sarcoma of soft tissue",
          "sarcoma of the soft tissue",
          "soft part sarcoma",
          "soft tissue sarcoma"
        ],
        "definition": "A malignant neoplasm arising from muscle tissue, adipose tissue, blood vessels, fibrous tissue, or other supportive tissues excluding the bones."
      },
      "child_count": 92,
      "reference_id": "MONDO:0018078"
    }
  ],
  "children": [
    {
      "id": 4068,
      "label": "spinal cord sarcoma",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        4336,
        5449
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:14152",
          "GARD:0023032",
          "MEDGEN:233459",
          "NCIT:C5152",
          "UMLS:C1336049"
        ],
        "synonyms": [
          "sarcoma of spinal cord",
          "sarcoma of the spinal cord",
          "spinal cord sarcoma"
        ],
        "categories": [
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "A sarcoma that arises from the spinal cord."
      },
      "child_count": 0,
      "reference_id": "MONDO:0001894"
    },
    {
      "id": 4335,
      "label": "brain sarcoma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        3853,
        4336
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:2132",
          "GARD:0023087",
          "MEDGEN:272381",
          "NCIT:C5154",
          "UMLS:C1332607"
        ],
        "synonyms": [
          "brain sarcoma",
          "primary brain sarcoma",
          "sarcoma of brain",
          "sarcoma of the brain"
        ],
        "categories": [
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "A sarcoma arising from the brain."
      },
      "child_count": 4,
      "reference_id": "MONDO:0002216"
    },
    {
      "id": 4864,
      "label": "central nervous system rhabdomyosarcoma",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        4336,
        6928
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:4048",
          "GARD:0023268",
          "MEDGEN:232043",
          "NCIT:C5464",
          "UMLS:C1332891"
        ],
        "synonyms": [
          "CNS rhabdomyosarcoma",
          "central nervous system rhabdomyosarcoma",
          "central nervous system rhabdomyosarcoma (disease)",
          "rhabdomyosarcoma (disease) of central nervous system",
          "rhabdomyosarcoma of CNS",
          "rhabdomyosarcoma of central nervous system",
          "rhabdomyosarcoma of the CNS",
          "rhabdomyosarcoma of the central nervous system"
        ],
        "categories": [
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "A malignant mesenchymal neoplasm with skeletal muscle differentiation affecting the central nervous system."
      },
      "child_count": 0,
      "reference_id": "MONDO:0002850"
    },
    {
      "id": 5014,
      "label": "central nervous system angiosarcoma",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        4336,
        17394,
        23165
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:4504",
          "GARD:0023329",
          "MEDGEN:272441",
          "NCIT:C5450",
          "UMLS:C1332875"
        ],
        "synonyms": [
          "CNS angiosarcoma",
          "CNS hemangiosarcoma",
          "angiosarcoma (disease) of central nervous system",
          "angiosarcoma of CNS",
          "angiosarcoma of central nervous system",
          "angiosarcoma of the CNS",
          "angiosarcoma of the central nervous system",
          "central nervous system angiosarcoma",
          "central nervous system angiosarcoma (disease)",
          "central nervous system hemangiosarcoma",
          "hemangiosarcoma of CNS",
          "hemangiosarcoma of central nervous system",
          "hemangiosarcoma of the CNS",
          "hemangiosarcoma of the central nervous system"
        ],
        "categories": [
          {
            "ref": "MONDO:0004995",
            "name": "cardiovascular disorder"
          },
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "A malignant vascular neoplasm arising from the brain, spinal cord or meninges."
      },
      "child_count": 0,
      "reference_id": "MONDO:0003021"
    },
    {
      "id": 5284,
      "label": "central nervous system leiomyosarcoma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        4336,
        6788,
        22971
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:5254",
          "GARD:0023465",
          "MEDGEN:235254",
          "NCIT:C6999",
          "UMLS:C1334385"
        ],
        "synonyms": [
          "CNS leiomyosarcoma",
          "central nervous system leiomyosarcoma",
          "leiomyosarcoma of CNS",
          "leiomyosarcoma of central nervous system",
          "leiomyosarcoma of the CNS",
          "leiomyosarcoma of the central nervous system"
        ],
        "categories": [
          {
            "ref": "MONDO:0002081",
            "name": "musculoskeletal system disorder"
          },
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "An aggressive malignant smooth muscle neoplasm, arising from the central nervous system. It is characterized by a proliferation of neoplastic spindle cells."
      },
      "child_count": 3,
      "reference_id": "MONDO:0003349"
    },
    {
      "id": 5745,
      "label": "central nervous system fibrosarcoma",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        4336,
        6886
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:6451",
          "GARD:0023713",
          "MEDGEN:232039",
          "NCIT:C5465",
          "UMLS:C1332879"
        ],
        "synonyms": [
          "CNS fibrosarcoma",
          "central nervous system fibrosarcoma",
          "central nervous system fibrosarcoma (disease)",
          "fibrosarcoma of CNS",
          "fibrosarcoma of central nervous system",
          "fibrosarcoma of the CNS",
          "fibrosarcoma of the central nervous system"
        ],
        "categories": [
          {
            "ref": "MONDO:0003900",
            "name": "connective tissue disorder"
          },
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "A usually aggressive malignant neoplasm arising from the central nervous system. It is characterized by the presence of spindle-shaped fibroblasts and collagenous stroma formation in a herringbone growth pattern."
      },
      "child_count": 0,
      "reference_id": "MONDO:0003882"
    },
    {
      "id": 6124,
      "label": "meningeal sarcoma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        4336,
        20501
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:7614",
          "GARD:0023924",
          "MEDGEN:90148",
          "NCIT:C4073",
          "UMLS:C0302327"
        ],
        "synonyms": [
          "meningeal cluster sarcoma",
          "meningeal sarcoma",
          "meninges sarcoma",
          "sarcoma of meningeal cluster",
          "sarcoma of meninges",
          "sarcoma of the meninges"
        ],
        "categories": [
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "A rare sarcoma arising from the meninges."
      },
      "child_count": 4,
      "reference_id": "MONDO:0004308"
    },
    {
      "id": 6203,
      "label": "intracranial extraskeletal myxoid chondrosarcoma",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        4336,
        13865,
        24270
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:7903",
          "GARD:0023973",
          "MEDGEN:232660",
          "NCIT:C5462",
          "UMLS:C1334238"
        ],
        "synonyms": [
          "intracranial extraskeletal myxoid chondrosarcoma",
          "intracranial chondrosarcoma"
        ],
        "categories": [
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "An extraskeletal myxoid chondrosarcoma arising from the structures within the cranium."
      },
      "child_count": 0,
      "reference_id": "MONDO:0004392"
    },
    {
      "id": 6232,
      "label": "central nervous system extraskeletal osteosarcoma",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        4336,
        4672,
        22971
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:7994",
          "GARD:0023997",
          "MEDGEN:233803",
          "NCIT:C7002",
          "UMLS:C1335150"
        ],
        "synonyms": [
          "central nervous system extraskeletal osteosarcoma",
          "central nervous system osteosarcoma (disease)",
          "osteosarcoma of central nervous system",
          "osteosarcoma of the central nervous system",
          "central nervous system osteosarcoma"
        ],
        "categories": [
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "An osteosarcoma arising from the brain or spinal cord."
      },
      "child_count": 0,
      "reference_id": "MONDO:0004423"
    },
    {
      "id": 18046,
      "label": "malignant peripheral nerve sheath tumor",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        4336,
        4613,
        17197,
        20329,
        24071
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:5940",
          "EFO:0000760",
          "GARD:0010872",
          "ICD9:171.9",
          "ICDO:9540/3",
          "ICDO:9560/3",
          "MEDGEN:155614",
          "MedDRA:10029236",
          "NANDO:2200102",
          "NCIT:C3798",
          "ONCOTREE:MPNST",
          "Orphanet:3148",
          "SCTID:404037002",
          "UMLS:C0751690",
          "icd11.foundation:71413945"
        ],
        "synonyms": [
          "neurofibrosarcoma",
          "MPNST",
          "Malig. periph. nerve sheath tum.",
          "malignant neoplasm of peripheral nerve sheath",
          "malignant neurilemmoma",
          "malignant neurilemoma",
          "malignant neurofibroma",
          "malignant peripheral nerve sheath neoplasm",
          "malignant peripheral nerve sheath tumor",
          "malignant peripheral nerve sheath tumor (morphologic abnormality)",
          "malignant peripheral nerve sheath tumor [dup] (morphologic abnormality)",
          "malignant peripheral nerve sheath tumour (morphologic abnormality)",
          "malignant peripheral nerve sheath tumour [dup] (morphologic abnormality)",
          "malignant schwannoma",
          "malignant tumor of peripheral nerve sheath",
          "malignant tumor of the peripheral nerve sheath",
          "malignant tumour of peripheral nerve sheath",
          "malignant tumour of the peripheral nerve sheath",
          "neurofibrosarcoma, malignant",
          "neurogenic sarcoma",
          "schwannoma, malignant"
        ],
        "categories": [
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "Malignant peripheral nerve sheath tumor (MPNST) is a rare and often aggressive soft tissue sarcoma occurring in a wide range of anatomical sites."
      },
      "child_count": 35,
      "reference_id": "MONDO:0017827"
    },
    {
      "id": 20002,
      "label": "atypical teratoid rhabdoid tumor",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        4336,
        4765
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:2129",
          "EFO:1002008",
          "GARD:0016926",
          "ICDO:9508/3",
          "MEDGEN:226853",
          "NANDO:2200101",
          "NCIT:C6906",
          "ONCOTREE:ATRT",
          "Orphanet:99966",
          "UMLS:C1266184"
        ],
        "synonyms": [
          "AT/RT",
          "ATRT",
          "ATT/RHT",
          "CNS rhabdoid neoplasm",
          "CNS rhabdoid tumor",
          "CNS rhabdoid tumour",
          "atypical teratoid/rhabdoid tumor",
          "atypical teratoid/rhabdoid tumor (WHO grade IV)",
          "atypical teratoid/rhabdoid tumor (morphologic abnormality)",
          "atypical teratoid/rhabdoid tumour (WHO grade IV)",
          "atypical teratoid/rhabdoid tumour (morphologic abnormality)",
          "central nervous system rhabdoid neoplasm",
          "central nervous system rhabdoid tumor",
          "central nervous system rhabdoid tumour",
          "malignant brain rhabdoid neoplasm",
          "malignant brain rhabdoid tumor",
          "malignant brain rhabdoid tumour",
          "malignant rhabdoid neoplasm of brain",
          "malignant rhabdoid neoplasm of the brain",
          "malignant rhabdoid tumor of brain",
          "malignant rhabdoid tumor of the brain",
          "malignant rhabdoid tumour of brain",
          "malignant rhabdoid tumour of the brain",
          "primary malignant brain rhabdoid neoplasm",
          "primary malignant brain rhabdoid tumor",
          "primary malignant brain rhabdoid tumour",
          "primary malignant rhabdoid neoplasm of brain",
          "primary malignant rhabdoid neoplasm of the brain",
          "primary malignant rhabdoid tumor of brain",
          "primary malignant rhabdoid tumor of the brain",
          "primary malignant rhabdoid tumour of brain",
          "primary malignant rhabdoid tumour of the brain",
          "rhabdoid neoplasm of CNS",
          "rhabdoid neoplasm of central nervous system",
          "rhabdoid neoplasm of the CNS",
          "rhabdoid neoplasm of the central nervous system",
          "rhabdoid tumor of CNS",
          "rhabdoid tumor of central nervous system",
          "rhabdoid tumor of the CNS",
          "rhabdoid tumor of the central nervous system",
          "rhabdoid tumour of CNS",
          "rhabdoid tumour of central nervous system",
          "rhabdoid tumour of the central nervous system",
          "rhabdoid tumor predisposition syndrome",
          "rhabdoid tumour predisposition syndrome"
        ],
        "categories": [
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "Atypical teratoid rhabdoid tumor (ATRT) is a highly malignant central nervous system (CNS) rhabdoid tumor (RT) found almost exclusively in children."
      },
      "child_count": 2,
      "reference_id": "MONDO:0020560"
    },
    {
      "id": 22804,
      "label": "isolated melanotic schwannoma",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        4336,
        4623,
        20329,
        24071
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0022368",
          "Orphanet:590539"
        ],
        "categories": [
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ]
      },
      "child_count": 0,
      "reference_id": "MONDO:0035136"
    }
  ],
  "roots": [
    {
      "id": 4753,
      "label": "central nervous system cancer"
    },
    {
      "id": 18239,
      "label": "soft tissue sarcoma"
    }
  ]
}