{
  "id": 4365,
  "label": "thrombocytosis disease",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0002249",
  "properties": {
    "xrefs": [
      "DOID:2228",
      "ICD9:289.9",
      "MEDGEN:163397",
      "MESH:D013922",
      "NCIT:C35530",
      "SCTID:6631009",
      "UMLS:C0836924"
    ],
    "synonyms": [
      "Platelet count increased",
      "elevated Platelet count",
      "thrombocytosis"
    ],
    "categories": [
      {
        "ref": "MONDO:0005570",
        "name": "hematologic disorder"
      }
    ],
    "definition": "A disease characterized by higher than normal platelet counts in the peripheral blood."
  },
  "isLeaf": false,
  "isRoot": false,
  "child_count": 3,
  "parents": [
    {
      "id": 4362,
      "label": "blood platelet disease",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        7217
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "MEDGEN:57492",
          "MESH:D001791",
          "NCIT:C131634",
          "SCTID:22716005",
          "UMLS:C0151854"
        ],
        "synonyms": [
          "platelet abnormality",
          "platelet disorder",
          "thrombocytopathy"
        ],
        "categories": [
          {
            "ref": "MONDO:0005570",
            "name": "hematologic disorder"
          }
        ],
        "definition": "Disorders caused by abnormalities in platelet count or function."
      },
      "child_count": 5,
      "reference_id": "MONDO:0002245"
    }
  ],
  "children": [
    {
      "id": 6763,
      "label": "essential thrombocythemia",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        4365,
        19727
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:2224",
          "EFO:0000479",
          "GARD:0006594",
          "ICD10CM:D47.3",
          "ICD9:238.71",
          "ICDO:9962/3",
          "MEDGEN:11797",
          "MESH:D013920",
          "MedDRA:10015493",
          "NANDO:2100194",
          "NANDO:2200655",
          "NCIT:C3407",
          "NORD:1110",
          "ONCOTREE:ET",
          "Orphanet:3318",
          "SCTID:109994006",
          "UMLS:C0040028"
        ],
        "synonyms": [
          "ET",
          "essential thrombocytemia",
          "essential thrombocythemia",
          "essential thrombocytosis",
          "primary thrombocythemia",
          "primary thrombocytosis",
          "idiopathic thrombocythemia"
        ],
        "categories": [
          {
            "ref": "MONDO:0002081",
            "name": "musculoskeletal system disorder"
          },
          {
            "ref": "MONDO:0003900",
            "name": "connective tissue disorder"
          },
          {
            "ref": "MONDO:0005046",
            "name": "immune system disorder"
          },
          {
            "ref": "MONDO:0005570",
            "name": "hematologic disorder"
          }
        ],
        "definition": "A chronic myeloproliferative neoplasm that involves primarily the megakaryocytic lineage. It is characterized by sustained thrombocytosis in the blood, increased numbers of large, mature megakaryocytes in the bone marrow, and episodes of thrombosis and/or hemorrhage. (WHO, 2008)"
      },
      "child_count": 0,
      "reference_id": "MONDO:0005029"
    },
    {
      "id": 18995,
      "label": "familial thrombocytosis",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        4365,
        5714
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0016688",
          "MEDGEN:929430",
          "OMIMPS:187950",
          "Orphanet:71493",
          "SCTID:720950009",
          "UMLS:C4303761",
          "icd11.foundation:1695088249"
        ],
        "synonyms": [
          "THCYT",
          "familial thrombocythemia",
          "hereditary thrombocythemia",
          "hereditary thrombocytosis",
          "hereditary thrombocytosis disease",
          "thrombocythemia"
        ],
        "categories": [
          {
            "ref": "MONDO:0005570",
            "name": "hematologic disorder"
          }
        ],
        "definition": "Familial thrombocytosis is a type of thrombocytosis, a sustained elevation of platelet numbers, which affects the platelet/megakaryocyte lineage and may create a tendency for thrombosis and hemorrhage but does not cause myeloproliferation."
      },
      "child_count": 6,
      "reference_id": "MONDO:0019111"
    },
    {
      "id": 21464,
      "label": "reactive thrombocytosis",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        4365
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0025409",
          "ICD9:286.9",
          "MEDGEN:630140",
          "SCTID:234500001",
          "UMLS:C0457506",
          "icd11.foundation:1096559251"
        ],
        "synonyms": [
          "secondary thrombocytosis"
        ],
        "categories": [
          {
            "ref": "MONDO:0005570",
            "name": "hematologic disorder"
          }
        ],
        "definition": "A thrombocytosis caused by an underlying condition, such as an infection."
      },
      "child_count": 0,
      "reference_id": "MONDO:0024518"
    }
  ],
  "roots": [
    {
      "id": 4362,
      "label": "blood platelet disease"
    }
  ]
}