{
  "id": 4373,
  "label": "ankylosis",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0002257",
  "properties": {
    "xrefs": [
      "DOID:227",
      "HP:0031013",
      "ICD9:718.5",
      "ICD9:718.50",
      "MEDGEN:8101",
      "MESH:D000844",
      "SCTID:111227009",
      "UMLS:C0003090"
    ],
    "synonyms": [
      "ankylosis",
      "ankylosis (disease)"
    ],
    "categories": [
      {
        "ref": "MONDO:0002081",
        "name": "musculoskeletal system disorder"
      }
    ],
    "definition": "Fixation and immobility of a joint."
  },
  "isLeaf": false,
  "isRoot": false,
  "child_count": 2,
  "parents": [
    {
      "id": 8264,
      "label": "arthropathy",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6893
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:381",
          "EFO:1000999",
          "ICD9:711",
          "ICD9:716.80",
          "ICD9:716.88",
          "ICD9:716.9",
          "ICD9:716.90",
          "ICD9:716.98",
          "ICD9:719.80",
          "ICD9:719.88",
          "ICD9:719.89",
          "ICD9:719.9",
          "ICD9:719.90",
          "ICD9:719.98",
          "MEDGEN:7190",
          "MESH:D007592",
          "MedDRA:10003285",
          "NCIT:C35760",
          "SCTID:399269003",
          "UMLS:C0022408"
        ],
        "synonyms": [
          "Joint disorder",
          "arthropathy",
          "disease of skeletal joint",
          "disease or disorder of skeletal joint",
          "disorder of skeletal joint",
          "disorder, Joint",
          "skeletal joint disease",
          "skeletal joint disease or disorder",
          "Joint ankylosis of the ankle and foot",
          "Joint ankylosis of the forearm",
          "Joint ankylosis of the hand",
          "Joint ankylosis of the lower leg",
          "Joint ankylosis of the pelvic region and thigh",
          "Joint ankylosis of the shoulder region",
          "Joint ankylosis of the upper arm",
          "ankylosis of ankle and foot joint",
          "ankylosis of forearm joint",
          "ankylosis of hand joint",
          "ankylosis of joint of multiple sites",
          "ankylosis of joint of pelvic region and thigh",
          "ankylosis of joint of shoulder region",
          "ankylosis of lower leg joint",
          "ankylosis of multiple joints",
          "ankylosis of upper arm joint",
          "infectious arthropathy",
          "arthrosis",
          "disorder of joint",
          "joint disease",
          "joint disorder"
        ],
        "categories": [
          {
            "ref": "MONDO:0002081",
            "name": "musculoskeletal system disorder"
          }
        ],
        "definition": "Any disorder of the joints."
      },
      "child_count": 24,
      "reference_id": "MONDO:0006816"
    }
  ],
  "children": [
    {
      "id": 9333,
      "label": "tooth ankylosis",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        4339,
        4373,
        5714
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:12661",
          "GARD:0000701",
          "ICD10CM:K03.5",
          "ICD9:521.6",
          "MEDGEN:57843",
          "MESH:D020254",
          "MedDRA:10044019",
          "OMIM:157950",
          "Orphanet:1077",
          "SCTID:14901003",
          "UMLS:C0155930",
          "icd11.foundation:2066427602"
        ],
        "synonyms": [
          "ankylosis (disease) of calcareous tooth",
          "ankylosis of teeth",
          "ankylosis of tooth",
          "calcareous tooth ankylosis (disease)",
          "abnormal fusion of dental cementum with alveolar bone",
          "dental ankylosis",
          "molar 1 reinclusion",
          "molar I reinclusion",
          "permanent molars, secondary retention OF",
          "secondary retention of permanent molars"
        ],
        "categories": [
          {
            "ref": "MONDO:0002081",
            "name": "musculoskeletal system disorder"
          },
          {
            "ref": "MONDO:0006858",
            "name": "mouth disorder"
          }
        ],
        "definition": "Dental ankylosis is a rare disorder characterized by the fusion of the tooth to the bone, preventing both eruption and orthodontic movement."
      },
      "child_count": 0,
      "reference_id": "MONDO:0008007"
    },
    {
      "id": 16803,
      "label": "congenital temporomandibular joint ankylosis",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        4373,
        7131
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0020450",
          "MEDGEN:1638477",
          "Orphanet:210576",
          "SCTID:763215008",
          "UMLS:C4706319"
        ],
        "synonyms": [
          "congenital trismus"
        ],
        "categories": [
          {
            "ref": "MONDO:0002081",
            "name": "musculoskeletal system disorder"
          }
        ],
        "definition": "Congenital temporomandibular joint ankylosis is a rare maxillofacial disorder characterized by significant reduction in mouth opening (i.e. from a few millimeters to a few centimeters) in the absence of acquired factors (e.g. trauma, infection) contributing to the ankylosis. It is associated with variable degrees of facial dysmorphism (i.e. lateral deviation of the mandible and chin, lower facial asymmetry, retrognathia, micrognathia, dental malocclusion) and patients typically present with feeding and breathing difficulties. Developmental delay, hypotonia, seizures, and additional dysmorphic features (e.g. pectus excavatum, low-set ears, hypoplastic alae nasi) have also been reported."
      },
      "child_count": 0,
      "reference_id": "MONDO:0016220"
    }
  ],
  "roots": [
    {
      "id": 8264,
      "label": "arthropathy"
    }
  ]
}