{
  "id": 4391,
  "label": "arteriosclerosis disorder",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0002277",
  "properties": {
    "xrefs": [
      "CSP:0571-2299",
      "DOID:2348",
      "DOID:2349",
      "HP:0002634",
      "ICD9:440",
      "MEDGEN:2076",
      "MESH:D001161",
      "NCIT:C34398",
      "NCIT:C34403",
      "SCTID:72092001",
      "UMLS:C0003850"
    ],
    "synonyms": [
      "arterial sclerosis",
      "arteriosclerosis",
      "arteriosclerotic cardiovascular disease",
      "vascular sclerosis"
    ],
    "categories": [
      {
        "ref": "MONDO:0004995",
        "name": "cardiovascular disorder"
      }
    ],
    "definition": "A vascular disorder characterized by thickening and hardening of the walls of the arteries."
  },
  "isLeaf": false,
  "isRoot": false,
  "child_count": 5,
  "parents": [
    {
      "id": 2933,
      "label": "arterial disorder",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        7065
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0050828",
          "ICD9:447.8",
          "ICD9:447.9",
          "MEDGEN:208875",
          "NCIT:C35317",
          "SCTID:359557001",
          "UMLS:C0852949"
        ],
        "synonyms": [
          "arterial disease",
          "arterial disorder",
          "arteriopathy",
          "artery disease",
          "artery disease or disorder",
          "disease of artery",
          "disease or disorder of artery",
          "disorder of artery"
        ],
        "categories": [
          {
            "ref": "MONDO:0004995",
            "name": "cardiovascular disorder"
          }
        ],
        "definition": "An impairment of the structure or function of the blood vessels which carry blood away from the heart."
      },
      "child_count": 30,
      "reference_id": "MONDO:0000473"
    }
  ],
  "children": [
    {
      "id": 3828,
      "label": "intracranial arteriosclerosis",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        4391
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:13097",
          "MEDGEN:3319",
          "MESH:D002537",
          "UMLS:C0007771"
        ],
        "categories": [
          {
            "ref": "MONDO:0004995",
            "name": "cardiovascular disorder"
          }
        ],
        "definition": "Vascular diseases characterized by thickening and hardening of the walls of arteries inside the skull. There are three subtypes: (1) atherosclerosis with fatty deposits in the arterial intima; (2) Monckeberg's sclerosis with calcium deposits in the media and (3) arteriolosclerosis involving the small caliber arteries. Clinical signs include headache; confusion; transient blindness (amaurosis fugax); speech impairment; and hemiparesis."
      },
      "child_count": 0,
      "reference_id": "MONDO:0001632"
    },
    {
      "id": 5250,
      "label": "Monckeberg arteriosclerosis",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        4391
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:5161",
          "MEDGEN:165784",
          "NCIT:C35770",
          "UMLS:C0887866"
        ],
        "synonyms": [
          "Mönckeberg arteriosclerosis"
        ],
        "categories": [
          {
            "ref": "MONDO:0004995",
            "name": "cardiovascular disorder"
          }
        ],
        "definition": "A type of arteriosclerosis in which calcification of the tunica media is the predominant feature."
      },
      "child_count": 0,
      "reference_id": "MONDO:0003310"
    },
    {
      "id": 6989,
      "label": "intermittent vascular claudication",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        4391,
        6988
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:3669",
          "EFO:0003876",
          "ICD9:440.21",
          "MEDGEN:7115",
          "MESH:D007383",
          "SCTID:63491006",
          "UMLS:C0021775"
        ],
        "categories": [
          {
            "ref": "MONDO:0004995",
            "name": "cardiovascular disorder"
          }
        ],
        "definition": "A symptom complex characterized by pain and weakness in skeletal muscle group associated with exercise, such as leg pain and weakness brought on by walking. Such muscle limpness disappears after a brief rest and is often relates to arterial stenosis; muscle ischemia; and accumulation of lactate."
      },
      "child_count": 0,
      "reference_id": "MONDO:0005295"
    },
    {
      "id": 7003,
      "label": "atherosclerosis",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        4391
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:1936",
          "EFO:0003914",
          "ICD10CM:I70",
          "ICD10WHO:I70",
          "ICD9:440",
          "ICD9:440.8",
          "MEDGEN:13948",
          "MESH:D050197",
          "NCIT:C35768",
          "SCTID:441574008",
          "UMLS:C0004153",
          "icd11.foundation:109367356"
        ],
        "synonyms": [
          "atherosclerosis of artery",
          "atherosclerosis artery"
        ],
        "categories": [
          {
            "ref": "MONDO:0004995",
            "name": "cardiovascular disorder"
          }
        ],
        "definition": "A disease characterized by the build-up of fatty material and calcium deposition in the arterial wall resulting in partial or complete occlusion of the arterial lumen."
      },
      "child_count": 6,
      "reference_id": "MONDO:0005311"
    },
    {
      "id": 23068,
      "label": "arteriosclerotic retinopathy",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        4391,
        4419
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "ICD9:440.8",
          "MEDGEN:573178",
          "SCTID:95691008",
          "UMLS:C0339478"
        ],
        "synonyms": [
          "arteriosclerosis disorder of retina",
          "arteriosclerotic retinopathy",
          "retina arteriosclerosis disorder",
          "arteriosclerosis, retina",
          "retinal arteriosclerosis",
          "retinopathy, arteriosclerotic"
        ],
        "categories": [
          {
            "ref": "MONDO:0002022",
            "name": "disorder of orbital region"
          },
          {
            "ref": "MONDO:0004995",
            "name": "cardiovascular disorder"
          },
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          },
          {
            "ref": "MONDO:0024458",
            "name": "disorder of visual system"
          }
        ],
        "definition": "A arteriosclerosis disorder that involves the retina."
      },
      "child_count": 0,
      "reference_id": "MONDO:0042495"
    }
  ],
  "roots": [
    {
      "id": 2933,
      "label": "arterial disorder"
    }
  ]
}