{
  "id": 4435,
  "label": "testicular disorder",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0002329",
  "properties": {
    "xrefs": [
      "DOID:2519",
      "EFO:0009601",
      "ICD9:608.89",
      "MEDGEN:11743",
      "MESH:D013733",
      "NCIT:C26890",
      "SCTID:64910008",
      "UMLS:C0039584"
    ],
    "synonyms": [
      "disease of testis",
      "disease or disorder of testis",
      "disorder of testis",
      "testicular disease",
      "testicular disorder",
      "testis disease",
      "testis disease or disorder"
    ],
    "categories": [
      {
        "ref": "MONDO:0005039",
        "name": "reproductive system disorder"
      },
      {
        "ref": "MONDO:0005151",
        "name": "endocrine system disorder"
      }
    ],
    "definition": "A non-neoplastic or neoplastic disorder affecting the testis. Representative examples include torsion, infarction, germ cell tumor, sex cord-stromal tumor, lymphoma, and leukemia."
  },
  "isLeaf": false,
  "isRoot": false,
  "child_count": 8,
  "parents": [
    {
      "id": 4375,
      "label": "gonadal disorder",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6772,
        6875
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:2277",
          "MEDGEN:9074",
          "MESH:D006058",
          "NCIT:C26786",
          "UMLS:C0018050"
        ],
        "synonyms": [
          "disease of gonad",
          "disease or disorder of gonad",
          "disorder of gonad",
          "disorder of gonads",
          "gonad disease",
          "gonad disease or disorder",
          "gonadal disorder",
          "gonadal disorders"
        ],
        "categories": [
          {
            "ref": "MONDO:0005039",
            "name": "reproductive system disorder"
          },
          {
            "ref": "MONDO:0005151",
            "name": "endocrine system disorder"
          }
        ],
        "definition": "A non-neoplastic or neoplastic disorder that affects the testis or the ovary."
      },
      "child_count": 12,
      "reference_id": "MONDO:0002259"
    },
    {
      "id": 5121,
      "label": "male reproductive system disorder",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6772
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:48",
          "EFO:0009555",
          "ICD10CM:N40-N53",
          "ICD10WHO:N40-N51",
          "ICD9:600-608",
          "ICD9:608.9",
          "MEDGEN:66734",
          "MESH:D005832",
          "NCIT:C27019",
          "SCTID:363194005",
          "UMLS:C0236099"
        ],
        "synonyms": [
          "Male reproductive system disease",
          "Male reproductive system disorder",
          "disease of male reproductive system",
          "disease or disorder of male reproductive system",
          "disorder of Male reproductive system",
          "disorder of male reproductive system",
          "male reproductive disease",
          "male reproductive system disease",
          "male reproductive system disease or disorder"
        ],
        "categories": [
          {
            "ref": "MONDO:0005039",
            "name": "reproductive system disorder"
          }
        ],
        "definition": "A disease involving the male reproductive system."
      },
      "child_count": 26,
      "reference_id": "MONDO:0003150"
    }
  ],
  "children": [
    {
      "id": 3382,
      "label": "chylocele of tunica vaginalis",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        4435
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:10835",
          "ICD9:608.84",
          "MEDGEN:510239",
          "SCTID:7864001",
          "UMLS:C0156315"
        ],
        "categories": [
          {
            "ref": "MONDO:0005039",
            "name": "reproductive system disorder"
          },
          {
            "ref": "MONDO:0005151",
            "name": "endocrine system disorder"
          }
        ]
      },
      "child_count": 0,
      "reference_id": "MONDO:0001136"
    },
    {
      "id": 3636,
      "label": "atrophy of testis",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        4435
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:11994",
          "ICD10CM:N50.0",
          "ICD9:608.3",
          "MEDGEN:57626",
          "NCIT:C123259",
          "SCTID:17585008",
          "UMLS:C0156312",
          "icd11.foundation:1735709719"
        ],
        "synonyms": [
          "testicular atrophy"
        ],
        "categories": [
          {
            "ref": "MONDO:0005039",
            "name": "reproductive system disorder"
          },
          {
            "ref": "MONDO:0005151",
            "name": "endocrine system disorder"
          }
        ],
        "definition": "Loss of testicular volume."
      },
      "child_count": 0,
      "reference_id": "MONDO:0001415"
    },
    {
      "id": 5220,
      "label": "testicular infarct",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        4435
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:5104",
          "MEDGEN:95919",
          "NCIT:C27617",
          "SCTID:33793000",
          "UMLS:C0392041"
        ],
        "synonyms": [
          "testicular infarction"
        ],
        "categories": [
          {
            "ref": "MONDO:0005039",
            "name": "reproductive system disorder"
          },
          {
            "ref": "MONDO:0005151",
            "name": "endocrine system disorder"
          }
        ],
        "definition": "Ischemic necrosis of the testis usually caused by torsion of the spermatic cord, trauma, or severe epididymo-orchitis."
      },
      "child_count": 0,
      "reference_id": "MONDO:0003279"
    },
    {
      "id": 7104,
      "label": "testicular dysgenesis syndrome",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        4130,
        4435
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "EFO:0004893",
          "GARD:0024185",
          "MEDGEN:754060",
          "NANDO:2200383",
          "SCTID:445338005",
          "UMLS:C2919755"
        ],
        "categories": [
          {
            "ref": "MONDO:0005039",
            "name": "reproductive system disorder"
          },
          {
            "ref": "MONDO:0005151",
            "name": "endocrine system disorder"
          }
        ],
        "definition": "A syndrome comprising testicular germ cell cancer, cryptorchidism and some cases of hypospadias and male infertility with impaired development of the testis."
      },
      "child_count": 0,
      "reference_id": "MONDO:0005437"
    },
    {
      "id": 8321,
      "label": "orchitis",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        4435,
        20399
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:2518",
          "EFO:1001078",
          "HP:0100796",
          "ICD10CM:N45.2",
          "MEDGEN:18191",
          "MESH:D009920",
          "MedDRA:10031064",
          "NCIT:C97145",
          "SCTID:274718005",
          "UMLS:C0029191"
        ],
        "synonyms": [
          "orchitis",
          "orchitis (disease)",
          "testis inflammation",
          "testisitis"
        ],
        "categories": [
          {
            "ref": "MONDO:0005039",
            "name": "reproductive system disorder"
          },
          {
            "ref": "MONDO:0005151",
            "name": "endocrine system disorder"
          }
        ],
        "definition": "Inflammation of one or both testes due to viral or bacterial infections. Signs and symptoms include enlargement or tenderness of the affected testis, inguinal lymphadenopathy, blood in the semen, and pain during urination, intercourse, or ejaculation."
      },
      "child_count": 6,
      "reference_id": "MONDO:0006882"
    },
    {
      "id": 9830,
      "label": "spermatic cord torsion",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        4435,
        5714
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:11996",
          "ICD10CM:N44.0",
          "ICD9:608.2",
          "ICD9:608.20",
          "MEDGEN:52446",
          "MESH:D013086",
          "NCIT:C26885",
          "OMIM:187400",
          "SCTID:81996005",
          "UMLS:C0037856"
        ],
        "synonyms": [
          "testicular torsion",
          "torsion of testis",
          "torsion of testicular cord"
        ],
        "categories": [
          {
            "ref": "MONDO:0005039",
            "name": "reproductive system disorder"
          },
          {
            "ref": "MONDO:0005151",
            "name": "endocrine system disorder"
          }
        ],
        "definition": "An emergency condition caused by the twisting of the spermatic cord which contains the vessels that provide the blood supply to the testis and surrounding structures. It manifests with acute testicular pain. If immediate medical assistance is not provided, it will lead to necrosis and loss of the testicular tissue."
      },
      "child_count": 0,
      "reference_id": "MONDO:0008541"
    },
    {
      "id": 20517,
      "label": "neoplasm of testis",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        4435,
        21521
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "ICD9:239.5",
          "MEDGEN:52675",
          "NCIT:C3404",
          "ONCOTREE:TESTIS",
          "SCTID:126900000",
          "UMLS:C0039590"
        ],
        "synonyms": [
          "neoplasm of testis",
          "neoplasm of the testis",
          "testicular neoplasm",
          "testicular tumor",
          "testicular tumour",
          "testis neoplasm",
          "testis neoplasm (disease)",
          "testis tumor",
          "testis tumour",
          "tumor of testis",
          "tumor of the testis",
          "tumour of testis",
          "tumour of the testis"
        ],
        "categories": [
          {
            "ref": "MONDO:0005039",
            "name": "reproductive system disorder"
          },
          {
            "ref": "MONDO:0005151",
            "name": "endocrine system disorder"
          }
        ],
        "definition": "A neoplasm (disease) that involves the testis."
      },
      "child_count": 16,
      "reference_id": "MONDO:0021348"
    },
    {
      "id": 21230,
      "label": "acquired testicular failure",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        4435
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "MEDGEN:588672",
          "NCIT:C131091",
          "SCTID:236811002",
          "UMLS:C0403818"
        ],
        "synonyms": [
          "acquired testicular failure"
        ],
        "categories": [
          {
            "ref": "MONDO:0005039",
            "name": "reproductive system disorder"
          },
          {
            "ref": "MONDO:0005151",
            "name": "endocrine system disorder"
          }
        ],
        "definition": "Testicular failure, the cause of which is not present at birth."
      },
      "child_count": 0,
      "reference_id": "MONDO:0023554"
    }
  ],
  "roots": [
    {
      "id": 4375,
      "label": "gonadal disorder"
    },
    {
      "id": 5121,
      "label": "male reproductive system disorder"
    }
  ]
}