{
  "id": 4440,
  "label": "hematopoietic and lymphoid system neoplasm",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0002334",
  "properties": {
    "xrefs": [
      "DOID:2531",
      "GARD:0023120",
      "MEDGEN:268180",
      "MESH:D019337",
      "NCIT:C35813",
      "SCTID:129154003",
      "UMLS:C1512393"
    ],
    "synonyms": [
      "haematopoietic neoplasm",
      "haematopoietic neoplasm (morphologic abnormality)",
      "hematologic neoplasm",
      "hematopoietic neoplasm",
      "hematopoietic neoplasm (morphologic abnormality)",
      "blood neoplasm (disease)",
      "blood tumor",
      "blood tumour",
      "haematological tumours",
      "haematopoietic and lymphoid system tumour",
      "haematopoietic system neoplasm",
      "haematopoietic system tumour",
      "haematopoietic tumours",
      "hematopoietic and lymphoid system neoplasm",
      "hematopoietic and lymphoid system tumor",
      "hematopoietic system neoplasm",
      "hematopoietic system tumor",
      "neoplasm of blood",
      "neoplasm of haematopoietic system",
      "neoplasm of hematopoietic system",
      "tumor of blood",
      "tumor of hematopoietic system",
      "tumour of blood",
      "tumour of haematopoietic system",
      "blood cancer",
      "haematopoietic cancer",
      "hematologic malignancy",
      "hematopoietic cancer",
      "malignant haematopoietic neoplasm (morphologic abnormality)",
      "malignant hematopoietic neoplasm (morphologic abnormality)",
      "hematologic cancer",
      "malignant haematopoietic neoplasm"
    ],
    "categories": [
      {
        "ref": "MONDO:0005570",
        "name": "hematologic disorder"
      }
    ],
    "definition": "Neoplasms of the hematopoietic system, including hematopoietic cell neoplasms (e.g. leukemias, lymphomas) and non-hematopoietic cell neoplasms that can affect the hematopoietic system (e.g. lymph node and splenic sarcomas). --2003"
  },
  "isLeaf": false,
  "isRoot": false,
  "child_count": 9,
  "parents": [
    {
      "id": 6798,
      "label": "neoplasm",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        21214
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:14566",
          "EFO:0000616",
          "HP:0002664",
          "ICD10CM:C00-D49",
          "ICD10CM:C7A-C7A",
          "ICD10CM:C7B-C7B",
          "ICD9:140-239",
          "ICD9:239.8",
          "ICD9:239.9",
          "MEDGEN:10294",
          "MESH:D009369",
          "NCIT:C3262",
          "ONCOTREE:OTHER",
          "SCTID:55342001",
          "UMLS:C0027651"
        ],
        "synonyms": [
          "cell process disease",
          "disease of cellular proliferation",
          "neoplasia",
          "neoplasm",
          "neoplasm (disease)",
          "neoplastic disease",
          "neoplastic growth",
          "tumor",
          "tumor disease",
          "tumour",
          "tumour disease",
          "other neoplasm"
        ],
        "definition": "A benign or malignant tissue growth resulting from uncontrolled cell proliferation. Benign neoplastic cells resemble normal cells without exhibiting significant cytologic atypia, while malignant cells exhibit overt signs such as dysplastic features, atypical mitotic figures, necrosis, nuclear pleomorphism, and anaplasia. Representative examples of benign neoplasms include papillomas, cystadenomas, and lipomas; malignant neoplasms include carcinomas, sarcomas, lymphomas, and leukemias."
      },
      "child_count": 48,
      "reference_id": "MONDO:0005070"
    },
    {
      "id": 7217,
      "label": "hematologic disorder",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        29379
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:74",
          "EFO:0005803",
          "GTR:AN1320635",
          "ICD10CM:D50-D89",
          "ICD9:280-289",
          "ICD9:289.8",
          "ICD9:289.9",
          "MEDGEN:5483",
          "MESH:D006402",
          "NANDO:1100006",
          "NANDO:2100175",
          "NCIT:C26323",
          "Orphanet:97992",
          "SCTID:414022008",
          "UMLS:C0018939"
        ],
        "synonyms": [
          "blood disease",
          "blood disorder",
          "disease of hematopoietic system",
          "disease of the blood and blood-forming organs",
          "disease or disorder of haematopoietic system",
          "disease or disorder of hematopoietic system",
          "disorder of haematopoietic system",
          "disorder of hematopoietic system",
          "haematological disease",
          "haematological disorder",
          "haematological system disease",
          "haematopoietic disease",
          "haematopoietic system disease or disorder",
          "hematologic and lymphocytic disorder",
          "hematologic disorder",
          "hematological disease",
          "hematological disorder",
          "hematological system disease",
          "hematopoietic disease",
          "hematopoietic system disease",
          "hematopoietic system disease or disorder",
          "rare hematologic disease",
          "haematological disorders and malignancies",
          "hematological disorders and malignancies"
        ],
        "categories": [
          {
            "ref": "MONDO:0005570",
            "name": "hematologic disorder"
          }
        ],
        "definition": "A disease involving the hematopoietic system."
      },
      "child_count": 27,
      "reference_id": "MONDO:0005570"
    }
  ],
  "children": [
    {
      "id": 5125,
      "label": "cavernous hemangioma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        4440,
        5128,
        7994
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:483",
          "EFO:1000151",
          "GARD:0023388",
          "HP:0001048",
          "ICDO:9121/0",
          "MEDGEN:9184",
          "MESH:D006392",
          "NCIT:C3086",
          "SCTID:416824008",
          "UMLS:C0018920"
        ],
        "synonyms": [
          "cavernoma",
          "cavernous angioma",
          "cavernous hemangioma",
          "cavernous hemangioma (morphologic abnormality)"
        ],
        "categories": [
          {
            "ref": "MONDO:0004995",
            "name": "cardiovascular disorder"
          },
          {
            "ref": "MONDO:0005570",
            "name": "hematologic disorder"
          }
        ],
        "definition": "A hemangioma characterized by the presence of cavernous vascular spaces."
      },
      "child_count": 21,
      "reference_id": "MONDO:0003155"
    },
    {
      "id": 6916,
      "label": "thymus neoplasm",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        4223,
        4440,
        5325
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "EFO:0002626",
          "GARD:0019767",
          "ICD9:239.89",
          "MEDGEN:811424",
          "NCIT:C3412",
          "ONCOTREE:THYMUS",
          "Orphanet:100100",
          "SCTID:127231009",
          "UMLS:C3714644"
        ],
        "synonyms": [
          "Thymus neoplasm",
          "Thymus tumor",
          "Thymus tumour",
          "neoplasm of Thymus",
          "neoplasm of the Thymus",
          "neoplasm of thymus",
          "thymic neoplasm",
          "thymic tumor",
          "thymic tumour",
          "thymus neoplasm (disease)",
          "thymus tumor",
          "thymus tumour",
          "tumor of Thymus",
          "tumor of the Thymus",
          "tumor of thymus",
          "tumour of Thymus",
          "tumour of the Thymus",
          "tumour of thymus",
          "THYMUS"
        ],
        "categories": [
          {
            "ref": "MONDO:0005046",
            "name": "immune system disorder"
          },
          {
            "ref": "MONDO:0005151",
            "name": "endocrine system disorder"
          },
          {
            "ref": "MONDO:0005570",
            "name": "hematologic disorder"
          }
        ],
        "definition": "A neoplasm that affects the thymus. Representative examples include thymoma and carcinoma."
      },
      "child_count": 12,
      "reference_id": "MONDO:0005197"
    },
    {
      "id": 7055,
      "label": "bone marrow neoplasm",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        4440,
        5177
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:4960",
          "GARD:0024177",
          "ICD9:238.79",
          "MEDGEN:129203",
          "MESH:D019046",
          "NCIT:C35370",
          "SCTID:414824005",
          "UMLS:C0282609"
        ],
        "synonyms": [
          "bone marrow neoplasm",
          "bone marrow neoplasm (disease)",
          "bone marrow tumor",
          "bone marrow tumour",
          "neoplasm of bone marrow",
          "tumor of bone marrow",
          "tumour of bone marrow",
          "bone marrow cancer",
          "malignant bone marrow tumor",
          "malignant bone marrow tumour"
        ],
        "categories": [
          {
            "ref": "MONDO:0002081",
            "name": "musculoskeletal system disorder"
          },
          {
            "ref": "MONDO:0005046",
            "name": "immune system disorder"
          },
          {
            "ref": "MONDO:0005570",
            "name": "hematologic disorder"
          }
        ],
        "definition": "Neoplasms that affect the bone marrow. Such neoplasms may arise in the bone marrow (e.g. myeloid leukemias) or may involve the bone marrow as secondary, metastatic tumors (e.g. metastatic carcinomas to the bone marrow)."
      },
      "child_count": 2,
      "reference_id": "MONDO:0005374"
    },
    {
      "id": 15416,
      "label": "STAT3-related early-onset multisystem autoimmune disease",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        2772,
        4440
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0061160",
          "GARD:0017737",
          "MEDGEN:863232",
          "NCIT:C157123",
          "OMIM:615952",
          "Orphanet:438159",
          "UMLS:C4014795"
        ],
        "synonyms": [
          "ADMIO",
          "ADMIO1",
          "autoimmune disease, multisystem, infantile-onset",
          "autoimmune disease, multisystem, infantile-onset, 1"
        ],
        "categories": [
          {
            "ref": "MONDO:0005046",
            "name": "immune system disorder"
          },
          {
            "ref": "MONDO:0005570",
            "name": "hematologic disorder"
          }
        ]
      },
      "child_count": 0,
      "reference_id": "MONDO:0014414"
    },
    {
      "id": 16513,
      "label": "myeloid hemopathy",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        4440
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0020130",
          "MEDGEN:1842523",
          "Orphanet:171895",
          "UMLS:C5680514"
        ],
        "categories": [
          {
            "ref": "MONDO:0005570",
            "name": "hematologic disorder"
          }
        ]
      },
      "child_count": 4,
      "reference_id": "MONDO:0015756"
    },
    {
      "id": 16514,
      "label": "lymphoid hemopathy",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        4440
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0020131",
          "MEDGEN:1842533",
          "Orphanet:171898",
          "UMLS:C5680515"
        ],
        "categories": [
          {
            "ref": "MONDO:0005570",
            "name": "hematologic disorder"
          }
        ]
      },
      "child_count": 4,
      "reference_id": "MONDO:0015757"
    },
    {
      "id": 21368,
      "label": "lymph node neoplasm",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        4440,
        6675
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0006932",
          "MEDGEN:108920",
          "NCIT:C35497",
          "UMLS:C0596869"
        ],
        "synonyms": [
          "lymph node neoplasm",
          "lymph node neoplasm (disease)",
          "lymph node tumor",
          "lymph node tumour",
          "neoplasm of lymph node",
          "tumor of lymph node",
          "tumour of lymph node"
        ],
        "categories": [
          {
            "ref": "MONDO:0005046",
            "name": "immune system disorder"
          },
          {
            "ref": "MONDO:0005570",
            "name": "hematologic disorder"
          }
        ],
        "definition": "A neoplasm involving a lymph node."
      },
      "child_count": 6,
      "reference_id": "MONDO:0024339"
    },
    {
      "id": 22946,
      "label": "spleen neoplasm",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        4438,
        4440
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0007683",
          "MEDGEN:21292",
          "NCIT:C3383",
          "UMLS:C0037999"
        ],
        "synonyms": [
          "neoplasm of spleen",
          "spleen tumor",
          "spleen tumour",
          "splenic neoplasm",
          "tumor of spleen",
          "tumour of spleen"
        ],
        "categories": [
          {
            "ref": "MONDO:0005046",
            "name": "immune system disorder"
          },
          {
            "ref": "MONDO:0005570",
            "name": "hematologic disorder"
          }
        ],
        "definition": "A benign or malignant neoplasm that affects the spleen. Representative examples include hemangioma, lymphoma, splenic involvement by leukemia, and angiosarcoma."
      },
      "child_count": 6,
      "reference_id": "MONDO:0036696"
    },
    {
      "id": 23467,
      "label": "hematopoietic and lymphoid cell neoplasm",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        4440
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0025916",
          "MEDGEN:91264",
          "NCIT:C27134",
          "UMLS:C0376544"
        ],
        "synonyms": [
          "HEMOLYMPHORETICULAR tumor, malignant",
          "haematological neoplasm",
          "haematological tumour",
          "haematopoietic and lymphoid neoplasms",
          "haematopoietic cancer",
          "haematopoietic cell tumour",
          "haematopoietic malignancy, NOS",
          "haematopoietic neoplasm",
          "haematopoietic neoplasms including lymphomas",
          "haematopoietic tumour",
          "hematologic cancer",
          "hematologic malignancy",
          "hematologic neoplasm",
          "hematological neoplasm",
          "hematological tumor",
          "hematopoietic and lymphoid cell neoplasm",
          "hematopoietic and lymphoid neoplasms",
          "hematopoietic cancer",
          "hematopoietic cell tumor",
          "hematopoietic malignancy, NOS",
          "hematopoietic neoplasm",
          "hematopoietic neoplasms including lymphomas",
          "hematopoietic tumor",
          "hematopoietic, Including myeloma",
          "malignant haematopoietic neoplasm",
          "malignant hematologic neoplasm",
          "malignant hematopoietic neoplasm"
        ],
        "categories": [
          {
            "ref": "MONDO:0005570",
            "name": "hematologic disorder"
          }
        ],
        "definition": "A neoplasm arising from hematopoietic cells found in the bone marrow, peripheral blood, lymph nodes and spleen (organs of the hematopoietic system). Hematopoietic cell neoplasms can also involve other anatomic sites (e.g. central nervous system, gastrointestinal tract), either by metastasis, direct tumor infiltration, or neoplastic transformation of extranodal lymphoid tissues. The commonest forms are the various types of leukemia, Hodgkin and non-Hodgkin lymphomas, myeloproliferative neoplasms, and myelodysplastic syndromes."
      },
      "child_count": 8,
      "reference_id": "MONDO:0044881"
    }
  ],
  "roots": [
    {
      "id": 6798,
      "label": "neoplasm"
    },
    {
      "id": 7217,
      "label": "hematologic disorder"
    }
  ]
}