{
  "id": 4455,
  "label": "pancreas disorder",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0002356",
  "properties": {
    "xrefs": [
      "DOID:26",
      "EFO:0009605",
      "ICD10CM:K86.9",
      "ICD9:577.8",
      "ICD9:577.9",
      "MEDGEN:14583",
      "MESH:D010182",
      "NCIT:C26842",
      "SCTID:3855007",
      "UMLS:C0030286",
      "icd11.foundation:1726554290"
    ],
    "synonyms": [
      "disease of pancreas",
      "disease or disorder of pancreas",
      "disorder of pancreas",
      "pancreas disease",
      "pancreas disease or disorder",
      "pancreatic disorder",
      "disease, pancreatic",
      "diseases, pancreatic",
      "pancreatic disease"
    ],
    "categories": [
      {
        "ref": "MONDO:0004335",
        "name": "digestive system disorder"
      },
      {
        "ref": "MONDO:0005151",
        "name": "endocrine system disorder"
      }
    ],
    "definition": "A non-neoplastic or neoplastic disorder that affects the pancreas. Representative examples of non-neoplastic disorders include pancreatitis and pancreatic insufficiency. Representative examples of neoplastic disorders include cystadenomas, carcinomas, lymphomas, and neuroendocrine neoplasms."
  },
  "isLeaf": false,
  "isRoot": false,
  "child_count": 14,
  "parents": [
    {
      "id": 6151,
      "label": "digestive system disorder",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        29379
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:77",
          "ICD10CM:K00-K95",
          "ICD9:520-579",
          "ICD9:V47.3",
          "MEDGEN:892790",
          "MESH:D005767",
          "NANDO:1100013",
          "NCIT:C2990",
          "SCTID:53619000",
          "UMLS:C4023588",
          "icd11.foundation:1256772020"
        ],
        "synonyms": [
          "digestive disease",
          "digestive system disease",
          "digestive system disease or disorder",
          "digestive system disorder",
          "disease of digestive system",
          "disease or disorder of digestive system",
          "disorder of digestive system",
          "gastroenterological system disease",
          "gastroenterological system disorder",
          "gastrointestinal disorder",
          "gastrointestinal system disease",
          "gastrointestinal system disorder",
          "stomach or intestinal disorder"
        ],
        "categories": [
          {
            "ref": "MONDO:0004335",
            "name": "digestive system disorder"
          }
        ],
        "definition": "A disease or disorder that involves the digestive system."
      },
      "child_count": 31,
      "reference_id": "MONDO:0004335"
    },
    {
      "id": 6875,
      "label": "endocrine system disorder",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        29379
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:28",
          "EFO:0001379",
          "ICD9:259.8",
          "ICD9:259.9",
          "MEDGEN:4043",
          "MESH:D004700",
          "NANDO:1100009",
          "NANDO:2100109",
          "NCIT:C3009",
          "SCTID:362969004",
          "UMLS:C0014130"
        ],
        "synonyms": [
          "disease of endocrine system",
          "disease or disorder of endocrine system",
          "disorder of endocrine system",
          "endocrine disease",
          "endocrine disorder",
          "endocrine system disease",
          "endocrine system disease or disorder",
          "endocrine system disorder",
          "endocrinopathy",
          "thyroid or other glandular disorders"
        ],
        "categories": [
          {
            "ref": "MONDO:0005151",
            "name": "endocrine system disorder"
          }
        ],
        "definition": "A disease involving the endocrine system."
      },
      "child_count": 48,
      "reference_id": "MONDO:0005151"
    }
  ],
  "children": [
    {
      "id": 3331,
      "label": "pancreatic steatorrhea",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        3328,
        4455
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:10610",
          "ICD10CM:K90.3",
          "ICD9:579.4",
          "MEDGEN:508909",
          "SCTID:54576000",
          "UMLS:C0152166",
          "icd11.foundation:54334889"
        ],
        "synonyms": [
          "pancreatic steatorrhoea"
        ],
        "categories": [
          {
            "ref": "MONDO:0004335",
            "name": "digestive system disorder"
          },
          {
            "ref": "MONDO:0005151",
            "name": "endocrine system disorder"
          }
        ]
      },
      "child_count": 0,
      "reference_id": "MONDO:0001079"
    },
    {
      "id": 3873,
      "label": "pancreatic mucinous ductal ectasia",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        4455
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:13313",
          "MEDGEN:233831",
          "NCIT:C5717",
          "UMLS:C1335310"
        ],
        "categories": [
          {
            "ref": "MONDO:0004335",
            "name": "digestive system disorder"
          },
          {
            "ref": "MONDO:0005151",
            "name": "endocrine system disorder"
          }
        ]
      },
      "child_count": 0,
      "reference_id": "MONDO:0001683"
    },
    {
      "id": 3874,
      "label": "exocrine pancreatic insufficiency",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        4455
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:13316",
          "ICD10CM:K86.81",
          "ICD9:577.8",
          "MEDGEN:75647",
          "MESH:D010188",
          "NCIT:C84316",
          "SCTID:47367009",
          "UMLS:C0267963"
        ],
        "synonyms": [
          "exocrine pancreatic insufficiency",
          "exocrine pancreas insufficiency",
          "pancreatic insufficiency"
        ],
        "categories": [
          {
            "ref": "MONDO:0004335",
            "name": "digestive system disorder"
          },
          {
            "ref": "MONDO:0005151",
            "name": "endocrine system disorder"
          }
        ],
        "definition": "Inability of the exocrine pancreas to produce and secrete an adequate amount of digestive enzymes into the small intestine. Patients present with symptoms of malabsorption syndrome, abdominal discomfort, and bloating. Causes include chronic pancreatitis, cystic fibrosis, and autoimmune disorders."
      },
      "child_count": 1,
      "reference_id": "MONDO:0001684"
    },
    {
      "id": 4104,
      "label": "endocrine pancreas disorder",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        4455
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:1428",
          "ICD9:251",
          "MEDGEN:124407",
          "NCIT:C27067",
          "SCTID:17346000",
          "UMLS:C0271633"
        ],
        "synonyms": [
          "disease of endocrine pancreas",
          "disease or disorder of endocrine pancreas",
          "disorder of endocrine pancreas",
          "endocrine pancreas disease",
          "endocrine pancreas disease or disorder",
          "endocrine pancreas disorder",
          "disorder of islets of langerhans",
          "disorder of pancreatic islets"
        ],
        "categories": [
          {
            "ref": "MONDO:0004335",
            "name": "digestive system disorder"
          },
          {
            "ref": "MONDO:0005151",
            "name": "endocrine system disorder"
          }
        ],
        "definition": "A disease involving the endocrine pancreas."
      },
      "child_count": 12,
      "reference_id": "MONDO:0001933"
    },
    {
      "id": 6723,
      "label": "pancreatitis",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        4455,
        20399
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:4989",
          "EFO:0000278",
          "MEDGEN:14586",
          "MESH:D010195",
          "NCIT:C3306",
          "SCTID:75694006",
          "UMLS:C0030305"
        ],
        "synonyms": [
          "inflammation of pancreas",
          "pancreas inflammation"
        ],
        "categories": [
          {
            "ref": "MONDO:0004335",
            "name": "digestive system disorder"
          },
          {
            "ref": "MONDO:0005151",
            "name": "endocrine system disorder"
          }
        ],
        "definition": "Inflammation of the pancreas."
      },
      "child_count": 10,
      "reference_id": "MONDO:0004982"
    },
    {
      "id": 9494,
      "label": "annular pancreas",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        4455
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0060850",
          "GARD:0000705",
          "ICD10CM:Q45.1",
          "MEDGEN:56211",
          "MESH:C536376",
          "MedDRA:10071757",
          "NCIT:C98813",
          "OMIM:167750",
          "Orphanet:675",
          "SCTID:40315008",
          "UMLS:C0149955",
          "icd11.foundation:1311285827"
        ],
        "synonyms": [
          "pancreas, annular"
        ],
        "categories": [
          {
            "ref": "MONDO:0004335",
            "name": "digestive system disorder"
          },
          {
            "ref": "MONDO:0005151",
            "name": "endocrine system disorder"
          }
        ],
        "definition": "Annular pancreas is a distinct form of duodenal atresia in which the head of the pancreas forms a ring around the second portion of the duodenum."
      },
      "child_count": 0,
      "reference_id": "MONDO:0008183"
    },
    {
      "id": 14722,
      "label": "pancreatic triacylglycerol lipase deficiency",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        4455,
        4594
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0017401",
          "ICD9:277.89",
          "MEDGEN:482157",
          "NANDO:2200912",
          "NCIT:C129030",
          "OMIM:614338",
          "Orphanet:309031",
          "SCTID:78960005",
          "UMLS:C3280527",
          "icd11.foundation:349070670"
        ],
        "synonyms": [
          "pancreatic triglyceride lipase deficiency",
          "PL deficiency",
          "PNLIPD",
          "colipase, congenital absence of pancreatic",
          "lipase and colipase, congenital absence of pancreatic",
          "lipase and colipase, deficiency of",
          "lipase, congenital absence of pancreatic",
          "pancreatic colipase deficiency",
          "pancreatic lipase deficiency"
        ],
        "categories": [
          {
            "ref": "MONDO:0004335",
            "name": "digestive system disorder"
          },
          {
            "ref": "MONDO:0005151",
            "name": "endocrine system disorder"
          }
        ],
        "definition": "An autosomal recessive disorder caused by mutation(s) in the PNLIP gene, encoding pancreatic triacylglycerol lipase. The condition is characterized by absent or reduced pancreatic lipase."
      },
      "child_count": 4,
      "reference_id": "MONDO:0013700"
    },
    {
      "id": 17869,
      "label": "follicular cholangitis and pancreatitis",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        4455,
        6624
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0021236",
          "MEDGEN:1667817",
          "Orphanet:300552",
          "UMLS:C4749906"
        ],
        "synonyms": [
          "follicular pancreatocholangitis"
        ],
        "categories": [
          {
            "ref": "MONDO:0004335",
            "name": "digestive system disorder"
          },
          {
            "ref": "MONDO:0005151",
            "name": "endocrine system disorder"
          }
        ],
        "definition": "Follicular cholangitis and pancreatitis is a rare pancreatobiliary disease characterized by marked duct-centered lymphoid follicular inflammation that develops in both biliary and pancreatic ductal systems, mainly affecting the hilar bile ducts and the pancreatic head. Patients present with jaundice, abdominal pain, liver dysfunction, pruritus and/or weight loss. Histology shows lymphoplasmacytic infiltration with formation of numerous, large lymphpoid follicles around the affected bile and pancreatic ducts."
      },
      "child_count": 0,
      "reference_id": "MONDO:0017589"
    },
    {
      "id": 18006,
      "label": "congenital pancreatic cyst",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        4455
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0021361",
          "ICD10CM:Q45.2",
          "MEDGEN:574418",
          "Orphanet:313906",
          "SCTID:204808002",
          "UMLS:C0341480",
          "icd11.foundation:981856956"
        ],
        "synonyms": [
          "neonatal congenital pancreatic cyst",
          "true congenital pancreatic cyst"
        ],
        "categories": [
          {
            "ref": "MONDO:0004335",
            "name": "digestive system disorder"
          },
          {
            "ref": "MONDO:0005151",
            "name": "endocrine system disorder"
          }
        ]
      },
      "child_count": 0,
      "reference_id": "MONDO:0017783"
    },
    {
      "id": 18906,
      "label": "recurrent acute pancreatitis",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        4455,
        20092
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "MEDGEN:489943",
          "MedDRA:10033657",
          "NCIT:C184324",
          "Orphanet:64740",
          "SCTID:197458008",
          "UMLS:C0267937",
          "icd11.foundation:300900170"
        ],
        "categories": [
          {
            "ref": "MONDO:0004335",
            "name": "digestive system disorder"
          },
          {
            "ref": "MONDO:0005151",
            "name": "endocrine system disorder"
          }
        ],
        "definition": "Recurrent acute pancreatitis (RAP) is characterized by repeated attacks of acute pancreatitis (AP), which is defined as an acute inflammatory process of the pancreas with variable involvement of other regional tissues or remote organ systems."
      },
      "child_count": 0,
      "reference_id": "MONDO:0018989"
    },
    {
      "id": 18946,
      "label": "accessory pancreas",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        4455
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0000454",
          "MEDGEN:82737",
          "MESH:C536003",
          "Orphanet:674",
          "SCTID:79037006",
          "UMLS:C0266268",
          "icd11.foundation:240534435"
        ],
        "synonyms": [
          "pancreas accessorium"
        ],
        "categories": [
          {
            "ref": "MONDO:0004335",
            "name": "digestive system disorder"
          },
          {
            "ref": "MONDO:0005151",
            "name": "endocrine system disorder"
          }
        ],
        "definition": "Accessory pancreas is an asymptomatic embryopathy characterized by the presence of pancreatic tissue in other sites of the body such as the splenic pedicle, gonadic pedicles, intestinal mesentery, duodenum wall, upper jejunum, or, more rarely, the gastric wall, ileum, gallbladder or spleen."
      },
      "child_count": 0,
      "reference_id": "MONDO:0019034"
    },
    {
      "id": 20285,
      "label": "pancreatic neoplasm",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        4455,
        20434
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "EFO:0003860",
          "MEDGEN:18279",
          "MESH:D010190",
          "NCIT:C3305",
          "ONCOTREE:PANCREAS",
          "SCTID:126859007",
          "UMLS:C0030297"
        ],
        "synonyms": [
          "neoplasm of pancreas",
          "neoplasm of the pancreas",
          "pancreas neoplasm",
          "pancreas neoplasm (disease)",
          "pancreas tumor",
          "pancreas tumour",
          "pancreatic neoplasm",
          "pancreatic tumor",
          "pancreatic tumour",
          "tumor of pancreas",
          "tumor of the pancreas",
          "tumour of pancreas",
          "tumour of the pancreas",
          "pancreas"
        ],
        "categories": [
          {
            "ref": "MONDO:0004335",
            "name": "digestive system disorder"
          },
          {
            "ref": "MONDO:0005151",
            "name": "endocrine system disorder"
          }
        ],
        "definition": "A benign or malignant neoplasm involving the pancreas."
      },
      "child_count": 14,
      "reference_id": "MONDO:0021040"
    },
    {
      "id": 26267,
      "label": "acinar cystic transformation of the pancreas",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        4455
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "MEDGEN:459447",
          "Orphanet:695131",
          "UMLS:C2987221"
        ],
        "categories": [
          {
            "ref": "MONDO:0004335",
            "name": "digestive system disorder"
          },
          {
            "ref": "MONDO:0005151",
            "name": "endocrine system disorder"
          }
        ]
      },
      "child_count": 0,
      "reference_id": "MONDO:0979284"
    },
    {
      "id": 26276,
      "label": "lymphoepithelial cyst of the pancreas",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        4455
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "Orphanet:697132"
        ],
        "categories": [
          {
            "ref": "MONDO:0004335",
            "name": "digestive system disorder"
          },
          {
            "ref": "MONDO:0005151",
            "name": "endocrine system disorder"
          }
        ]
      },
      "child_count": 0,
      "reference_id": "MONDO:0979310"
    }
  ],
  "roots": [
    {
      "id": 6151,
      "label": "digestive system disorder"
    },
    {
      "id": 6875,
      "label": "endocrine system disorder"
    }
  ]
}