{
  "id": 4464,
  "label": "autonomic nervous system neoplasm",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0002366",
  "properties": {
    "xrefs": [
      "DOID:2621",
      "MEDGEN:231389",
      "NCIT:C5112",
      "UMLS:C1332356"
    ],
    "synonyms": [
      "autonomic nervous system neoplasm",
      "autonomic nervous system neoplasm (disease)",
      "autonomic nervous system neoplasms",
      "autonomic nervous system tumor",
      "autonomic nervous system tumour",
      "neoplasm of autonomic nervous system",
      "neoplasm of the autonomic nervous system",
      "tumor of autonomic nervous system",
      "tumor of the autonomic nervous system",
      "tumour of autonomic nervous system",
      "tumour of the autonomic nervous system"
    ],
    "categories": [
      {
        "ref": "MONDO:0005071",
        "name": "nervous system disorder"
      }
    ],
    "definition": "Benign and malignant neoplasms which arise from or directly involve the central or peripheral elements of the autonomic nervous system."
  },
  "isLeaf": false,
  "isRoot": false,
  "child_count": 3,
  "parents": [
    {
      "id": 3525,
      "label": "autonomic nervous system disorder",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        4657,
        5512
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:11465",
          "EFO:0009532",
          "ICD9:337.1",
          "ICD9:337.9",
          "MEDGEN:218837",
          "MESH:D001342",
          "SCTID:128123007",
          "SCTID:15241006",
          "UMLS:C1145628",
          "icd11.foundation:1397803237"
        ],
        "synonyms": [
          "autonomic nervous disease",
          "autonomic nervous system disease",
          "autonomic nervous system disease or disorder",
          "disease of autonomic nervous system",
          "disease or disorder of autonomic nervous system",
          "disorder of autonomic nervous system",
          "disorder of peripheral autonomic nervous system",
          "disorder of the autonomic nervous system",
          "autonomic peripheral nervous system diseases",
          "dysautonomia",
          "peripheral autonomic nervous system diseases",
          "ANS (autonomic nervous system) diseases",
          "ANS disease",
          "ANS diseases",
          "autonomic central nervous system diseases",
          "autonomic disease",
          "autonomic diseases",
          "autonomic dysfunction, segmental",
          "autonomic dysfunctions, segmental",
          "autonomic nervous system disorders",
          "central autonomic nervous system diseases",
          "disorders of the autonomic nervous system",
          "nervous system diseases, autonomic",
          "nervous system diseases, sympathetic",
          "segmental autonomic dysfunction",
          "segmental autonomic dysfunctions"
        ],
        "categories": [
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "A disease involving the autonomic nervous system."
      },
      "child_count": 26,
      "reference_id": "MONDO:0001292"
    },
    {
      "id": 3627,
      "label": "peripheral nervous system neoplasm",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        5512,
        20456
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:1192",
          "EFO:0002431",
          "ICD9:239.2",
          "MEDGEN:45817",
          "MESH:D010524",
          "NCIT:C3321",
          "ONCOTREE:PNS",
          "SCTID:126980002",
          "UMLS:C0031118"
        ],
        "synonyms": [
          "PNS neoplasm",
          "PNS neoplasms",
          "PNS tumor",
          "PNS tumour",
          "neoplasm of PNS",
          "neoplasm of peripheral nerve",
          "neoplasm of peripheral nervous system",
          "neoplasm of the PNS",
          "neoplasm of the peripheral nerve",
          "neoplasm of the peripheral nervous system",
          "neoplasms, PNS",
          "neoplasms, peripheral nervous system",
          "peripheral nerve neoplasm",
          "peripheral nerve tumor",
          "peripheral nerve tumour",
          "peripheral nervous system neoplasm",
          "peripheral nervous system neoplasm (disease)",
          "peripheral nervous system tumor",
          "peripheral nervous system tumour",
          "tumor of PNS",
          "tumor of peripheral nerve",
          "tumor of peripheral nervous system",
          "tumor of the PNS",
          "tumor of the peripheral nerve",
          "tumor of the peripheral nervous system",
          "tumour of PNS",
          "tumour of peripheral nerve",
          "tumour of peripheral nervous system",
          "tumour of the PNS",
          "tumour of the peripheral nerve",
          "tumour of the peripheral nervous system",
          "CNS-excluded nervous sys. cancer",
          "nerve sheath neoplasm",
          "nerve sheath tumors",
          "nerve sheath tumours"
        ],
        "categories": [
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "A benign or malignant neoplasm arising from a peripheral nerve or the perineural sheaths."
      },
      "child_count": 18,
      "reference_id": "MONDO:0001406"
    },
    {
      "id": 7694,
      "label": "central nervous system neoplasm",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        4657,
        20456
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "EFO:1000158",
          "MEDGEN:88335",
          "NCIT:C9293",
          "UMLS:C0085136"
        ],
        "synonyms": [
          "CNS neoplasm",
          "CNS tumor",
          "CNS tumour",
          "brain/spinal cord tumor",
          "brain/spinal cord tumour",
          "central nervous system neoplasm",
          "central nervous system neoplasm (disease)",
          "central nervous system tumor",
          "central nervous system tumour",
          "neoplasm of CNS",
          "neoplasm of central nervous system",
          "neoplasm of the central nervous system",
          "tumor of CNS",
          "tumor of central nervous system",
          "tumor of the CNS",
          "tumor of the central nervous system",
          "tumour of CNS",
          "tumour of central nervous system",
          "tumour of the CNS",
          "tumour of the central nervous system"
        ],
        "categories": [
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "A benign or malignant, primary or metastatic neoplasm that affects the brain, meninges, or spinal cord. Representative examples of primary neoplasms include astrocytoma, oligodendroglioma, ependymoma, and meningioma. Representative examples of metastatic neoplasms include carcinoma and leukemia."
      },
      "child_count": 20,
      "reference_id": "MONDO:0006130"
    }
  ],
  "children": [
    {
      "id": 2912,
      "label": "paraganglioma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        4464,
        19314,
        20691,
        24270
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0050773",
          "EFO:1000453",
          "GARD:0022770",
          "ICD9:239.7",
          "ICDO:8680/1",
          "MEDGEN:10571",
          "MESH:D010235",
          "NCIT:C3308",
          "ONCOTREE:PGNG",
          "SCTID:127027008",
          "UMLS:C0030421"
        ],
        "synonyms": [
          "Paraganglionic neoplasm",
          "Paraganglionic tumor",
          "Paraganglionic tumour",
          "neoplasm of paraganglion",
          "neoplasm of the paraganglion",
          "paraganglioma",
          "paragangliomas",
          "paraganglion neoplasm",
          "paraganglion tumor",
          "paraganglion tumour",
          "tumor of paraganglion",
          "tumor of the paraganglion",
          "tumour of paraganglion",
          "tumour of the paraganglion",
          "chemodectoma"
        ],
        "categories": [
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          },
          {
            "ref": "MONDO:0005151",
            "name": "endocrine system disorder"
          }
        ],
        "definition": "A benign or malignant neoplasm arising from paraganglia located along the sympathetic or parasympathetic nerves. Infrequently, it may arise outside the usual distribution of the sympathetic and parasympathetic paraganglia. Tumors arising from the adrenal gland medulla are called pheochromocytomas. Morphologically, paragangliomas usually display a nesting (Zellballen) growth pattern. There are no reliable morphologic criteria to distinguish between benign and malignant paragangliomas. The only definitive indicator of malignancy is the presence of regional or distant metastases."
      },
      "child_count": 48,
      "reference_id": "MONDO:0000448"
    },
    {
      "id": 4620,
      "label": "sympathetic neurilemmoma",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        4464,
        4612
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:3201",
          "GARD:0023164",
          "MEDGEN:236964",
          "NCIT:C5421",
          "UMLS:C1336543"
        ],
        "synonyms": [
          "sympathetic schwannoma"
        ],
        "categories": [
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "A benign tumor derived from schwann cells of the peripheral sympathetic nervous system, including the sympathetic plexus."
      },
      "child_count": 0,
      "reference_id": "MONDO:0002554"
    },
    {
      "id": 6767,
      "label": "ganglioneuroma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        3043,
        4464,
        7851,
        17182,
        20329,
        23497
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:4817",
          "EFO:0000500",
          "GARD:0020731",
          "HP:0003005",
          "ICD9:215.9",
          "ICDO:9490/0",
          "MEDGEN:6545",
          "MedDRA:10017709",
          "NCIT:C3049",
          "ONCOTREE:GN",
          "Orphanet:251992",
          "SCTID:116371000119107",
          "UMLS:C0017075",
          "birnlex:12617"
        ],
        "synonyms": [
          "ganglioneuroma",
          "ganglioneuroma (Schwannian Stroma-dominant)",
          "ganglioneuroma (disease)",
          "ganglioneuroma, benign",
          "neural Crest tumor, benign",
          "GN"
        ],
        "categories": [
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "A benign neuroblastic tumor of the sympathetic nervous system that occurs in childhood. Ganglioneuroma typically arises from the sympathetic trunk in the mediastinum. Histologic features include spindle cell proliferation (resembling a neurofibroma) and the presence of large ganglion cells. Common presenting features include a palpable abdominal mass, hepatomegaly, and a thoracic mass detected on routine chest X-ray."
      },
      "child_count": 6,
      "reference_id": "MONDO:0005033"
    }
  ],
  "roots": [
    {
      "id": 3525,
      "label": "autonomic nervous system disorder"
    },
    {
      "id": 3627,
      "label": "peripheral nervous system neoplasm"
    },
    {
      "id": 7694,
      "label": "central nervous system neoplasm"
    }
  ]
}