{
  "id": 4473,
  "label": "spleen angiosarcoma",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0002376",
  "properties": {
    "xrefs": [
      "DOID:265",
      "GARD:0023126",
      "ICD9:159.1",
      "MEDGEN:83426",
      "NCIT:C4564",
      "SCTID:187821001",
      "UMLS:C0346424"
    ],
    "synonyms": [
      "angiosarcoma (disease) of spleen",
      "angiosarcoma of spleen",
      "angiosarcoma of the spleen",
      "hemangiosarcoma of spleen",
      "hemangiosarcoma of the spleen",
      "spleen angiosarcoma (disease)",
      "splenic angiosarcoma",
      "splenic hemangiosarcoma"
    ],
    "categories": [
      {
        "ref": "MONDO:0004335",
        "name": "digestive system disorder"
      },
      {
        "ref": "MONDO:0004995",
        "name": "cardiovascular disorder"
      },
      {
        "ref": "MONDO:0005046",
        "name": "immune system disorder"
      },
      {
        "ref": "MONDO:0005570",
        "name": "hematologic disorder"
      }
    ],
    "definition": "A malignant vascular neoplasm arising from the spleen."
  },
  "isLeaf": true,
  "isRoot": false,
  "child_count": 0,
  "parents": [
    {
      "id": 7558,
      "label": "spleen cancer",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        3023,
        4587,
        22946
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:672",
          "EFO:0007491",
          "GARD:0024265",
          "ICD10CM:C26.1",
          "MEDGEN:102271",
          "MESH:D013160",
          "NCIT:C3539",
          "SCTID:127230005",
          "UMLS:C0153470",
          "icd11.foundation:347078862"
        ],
        "synonyms": [
          "spleen neoplasm",
          "splenic neoplasm",
          "cancer of spleen",
          "cancer of the spleen",
          "malignant neoplasm of spleen",
          "malignant neoplasm of the spleen",
          "malignant spleen neoplasm",
          "malignant splenic neoplasm",
          "malignant splenic tumor",
          "malignant splenic tumour",
          "malignant tumor of spleen",
          "malignant tumor of the spleen",
          "malignant tumour of the spleen",
          "spleen cancer",
          "splenic cancer"
        ],
        "categories": [
          {
            "ref": "MONDO:0004335",
            "name": "digestive system disorder"
          },
          {
            "ref": "MONDO:0005046",
            "name": "immune system disorder"
          },
          {
            "ref": "MONDO:0005570",
            "name": "hematologic disorder"
          }
        ],
        "definition": "A malignant neoplasm involving the spleen"
      },
      "child_count": 15,
      "reference_id": "MONDO:0005966"
    },
    {
      "id": 17394,
      "label": "angiosarcoma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        4233,
        18239
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0001816",
          "EFO:0003968",
          "GARD:0020900",
          "HP:0200058",
          "ICD9:171.9",
          "ICDO:9120/3",
          "MEDGEN:42385",
          "MESH:D006394",
          "MedDRA:10002476",
          "NCIT:C3088",
          "ONCOTREE:ANGS",
          "Orphanet:263413",
          "SCTID:403977003",
          "UMLS:C0018923"
        ],
        "synonyms": [
          "angiosarcoma",
          "angiosarcoma (disease)",
          "blood vessel sarcoma",
          "hemangiosarcoma",
          "hemangiosarcoma, malignant",
          "malignant angioendothelioma",
          "malignant hemangioendothelioma",
          "sarcoma of blood vessel",
          "vascular sarcoma"
        ],
        "categories": [
          {
            "ref": "MONDO:0004995",
            "name": "cardiovascular disorder"
          }
        ],
        "definition": "A malignant tumor arising from the endothelial cells of the blood vessels. Microscopically, it is characterized by frequently open vascular anastomosing and branching channels. The malignant cells that line the vascular channels are spindle or epithelioid and often display hyperchromatic nuclei. Angiosarcomas most frequently occur in the skin and breast. Patients with long-standing lymphedema are at increased risk of developing angiosarcoma."
      },
      "child_count": 38,
      "reference_id": "MONDO:0016982"
    }
  ],
  "children": [],
  "roots": [
    {
      "id": 7558,
      "label": "spleen cancer"
    },
    {
      "id": 17394,
      "label": "angiosarcoma"
    }
  ]
}