{
  "id": 4483,
  "label": "liver angiosarcoma",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0002387",
  "properties": {
    "xrefs": [
      "DOID:268",
      "GARD:0005813",
      "ICD10CM:C22.3",
      "ICDO:9124/3",
      "MEDGEN:138027",
      "NCIT:C4438",
      "ONCOTREE:LIAS",
      "SCTID:109844006",
      "UMLS:C0345907",
      "icd11.foundation:965491615"
    ],
    "synonyms": [
      "angiosarcoma (disease) of liver",
      "angiosarcoma of liver",
      "angiosarcoma of the liver",
      "hemangiosarcoma of liver",
      "hemangiosarcoma of the liver",
      "hepatic angiosarcoma",
      "hepatic hemangiosarcoma",
      "liver angiosarcoma",
      "liver angiosarcoma (disease)",
      "liver hemangiosarcoma",
      "primary angiosarcoma of liver",
      "primary angiosarcoma of the liver",
      "Lias"
    ],
    "categories": [
      {
        "ref": "MONDO:0004335",
        "name": "digestive system disorder"
      },
      {
        "ref": "MONDO:0004995",
        "name": "cardiovascular disorder"
      },
      {
        "ref": "MONDO:0005151",
        "name": "endocrine system disorder"
      }
    ],
    "definition": "A malignant vascular neoplasm arising from the liver."
  },
  "isLeaf": true,
  "isRoot": false,
  "child_count": 0,
  "parents": [
    {
      "id": 4487,
      "label": "liver sarcoma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        4735,
        18239
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:270",
          "GARD:0023130",
          "MEDGEN:87522",
          "NCIT:C4437",
          "SCTID:254601002",
          "UMLS:C0345906"
        ],
        "synonyms": [
          "hepatic sarcoma",
          "liver sarcoma",
          "sarcoma of liver",
          "sarcoma of the liver"
        ],
        "categories": [
          {
            "ref": "MONDO:0004335",
            "name": "digestive system disorder"
          },
          {
            "ref": "MONDO:0005151",
            "name": "endocrine system disorder"
          }
        ],
        "definition": "A malignant soft tissue neoplasm that arises from the liver. Representative examples include angiosarcoma, undifferentiated (embryonal) sarcoma, rhabdomyosarcoma, and leiomyosarcoma."
      },
      "child_count": 14,
      "reference_id": "MONDO:0002397"
    },
    {
      "id": 4495,
      "label": "hepatic vascular disorder",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6878,
        7065
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:272",
          "ICD9:573.8",
          "MEDGEN:140779",
          "NCIT:C35442",
          "SCTID:235878005",
          "UMLS:C0400923"
        ],
        "synonyms": [
          "hepatic vascular disorder",
          "liver vascular disorder"
        ],
        "categories": [
          {
            "ref": "MONDO:0004335",
            "name": "digestive system disorder"
          },
          {
            "ref": "MONDO:0004995",
            "name": "cardiovascular disorder"
          },
          {
            "ref": "MONDO:0005151",
            "name": "endocrine system disorder"
          }
        ],
        "definition": "A non-neoplastic or neoplastic vascular disorder that affects the liver. Representative examples include veno-occlusive disease, hemangioma, lymphangioma, and angiosarcoma."
      },
      "child_count": 22,
      "reference_id": "MONDO:0002405"
    },
    {
      "id": 17394,
      "label": "angiosarcoma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        4233,
        18239
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0001816",
          "EFO:0003968",
          "GARD:0020900",
          "HP:0200058",
          "ICD9:171.9",
          "ICDO:9120/3",
          "MEDGEN:42385",
          "MESH:D006394",
          "MedDRA:10002476",
          "NCIT:C3088",
          "ONCOTREE:ANGS",
          "Orphanet:263413",
          "SCTID:403977003",
          "UMLS:C0018923"
        ],
        "synonyms": [
          "angiosarcoma",
          "angiosarcoma (disease)",
          "blood vessel sarcoma",
          "hemangiosarcoma",
          "hemangiosarcoma, malignant",
          "malignant angioendothelioma",
          "malignant hemangioendothelioma",
          "sarcoma of blood vessel",
          "vascular sarcoma"
        ],
        "categories": [
          {
            "ref": "MONDO:0004995",
            "name": "cardiovascular disorder"
          }
        ],
        "definition": "A malignant tumor arising from the endothelial cells of the blood vessels. Microscopically, it is characterized by frequently open vascular anastomosing and branching channels. The malignant cells that line the vascular channels are spindle or epithelioid and often display hyperchromatic nuclei. Angiosarcomas most frequently occur in the skin and breast. Patients with long-standing lymphedema are at increased risk of developing angiosarcoma."
      },
      "child_count": 38,
      "reference_id": "MONDO:0016982"
    }
  ],
  "children": [],
  "roots": [
    {
      "id": 4487,
      "label": "liver sarcoma"
    },
    {
      "id": 4495,
      "label": "hepatic vascular disorder"
    },
    {
      "id": 17394,
      "label": "angiosarcoma"
    }
  ]
}