{
  "id": 4487,
  "label": "liver sarcoma",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0002397",
  "properties": {
    "xrefs": [
      "DOID:270",
      "GARD:0023130",
      "MEDGEN:87522",
      "NCIT:C4437",
      "SCTID:254601002",
      "UMLS:C0345906"
    ],
    "synonyms": [
      "hepatic sarcoma",
      "liver sarcoma",
      "sarcoma of liver",
      "sarcoma of the liver"
    ],
    "categories": [
      {
        "ref": "MONDO:0004335",
        "name": "digestive system disorder"
      },
      {
        "ref": "MONDO:0005151",
        "name": "endocrine system disorder"
      }
    ],
    "definition": "A malignant soft tissue neoplasm that arises from the liver. Representative examples include angiosarcoma, undifferentiated (embryonal) sarcoma, rhabdomyosarcoma, and leiomyosarcoma."
  },
  "isLeaf": false,
  "isRoot": false,
  "child_count": 7,
  "parents": [
    {
      "id": 4735,
      "label": "liver cancer",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        4587,
        20310,
        21432
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:3571",
          "GARD:0027613",
          "ICD9:155.0",
          "ICD9:155.2",
          "MEDGEN:87520",
          "NCIT:C34803",
          "SCTID:93870000",
          "UMLS:C0345904",
          "icd11.foundation:1605020868"
        ],
        "synonyms": [
          "cancer of liver",
          "hepatic cancer",
          "liver cancer",
          "malignant liver neoplasm",
          "malignant neoplasm of liver",
          "malignant neoplasm of liver, not specified as primary or secondary",
          "malignant neoplasm of liver, primary",
          "malignant tumour of liver",
          "primary liver cancer",
          "primary malignant liver neoplasm",
          "primary malignant neoplasm of liver",
          "primary cancer of liver",
          "primary tumor of the liver",
          "primary tumour of the liver"
        ],
        "categories": [
          {
            "ref": "MONDO:0004335",
            "name": "digestive system disorder"
          },
          {
            "ref": "MONDO:0005151",
            "name": "endocrine system disorder"
          }
        ],
        "definition": "An epithelial or non-epithelial malignant neoplasm that arises from the liver. Representative examples include hepatocellular carcinoma, intrahepatic cholangiocarcinoma, lymphoma, and sarcoma."
      },
      "child_count": 15,
      "reference_id": "MONDO:0002691"
    },
    {
      "id": 18239,
      "label": "soft tissue sarcoma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6816,
        21548
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0070663",
          "EFO:1001968",
          "GARD:0004898",
          "MEDGEN:1642116",
          "NCIT:C9306",
          "NORD:1953",
          "Orphanet:3394",
          "SCTID:424952003",
          "UMLS:C4551687"
        ],
        "synonyms": [
          "malignant soft tissue tumor",
          "malignant soft tissue tumour",
          "connective tissue sarcoma",
          "malignant mesenchymal tumor",
          "malignant mesenchymal tumour",
          "non-Rhabdo. soft tissue sarcoma",
          "sarcoma of soft tissue",
          "sarcoma of the soft tissue",
          "soft part sarcoma",
          "soft tissue sarcoma"
        ],
        "definition": "A malignant neoplasm arising from muscle tissue, adipose tissue, blood vessels, fibrous tissue, or other supportive tissues excluding the bones."
      },
      "child_count": 92,
      "reference_id": "MONDO:0018078"
    }
  ],
  "children": [
    {
      "id": 4483,
      "label": "liver angiosarcoma",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        4487,
        4495,
        17394
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:268",
          "GARD:0005813",
          "ICD10CM:C22.3",
          "ICDO:9124/3",
          "MEDGEN:138027",
          "NCIT:C4438",
          "ONCOTREE:LIAS",
          "SCTID:109844006",
          "UMLS:C0345907",
          "icd11.foundation:965491615"
        ],
        "synonyms": [
          "angiosarcoma (disease) of liver",
          "angiosarcoma of liver",
          "angiosarcoma of the liver",
          "hemangiosarcoma of liver",
          "hemangiosarcoma of the liver",
          "hepatic angiosarcoma",
          "hepatic hemangiosarcoma",
          "liver angiosarcoma",
          "liver angiosarcoma (disease)",
          "liver hemangiosarcoma",
          "primary angiosarcoma of liver",
          "primary angiosarcoma of the liver",
          "Lias"
        ],
        "categories": [
          {
            "ref": "MONDO:0004335",
            "name": "digestive system disorder"
          },
          {
            "ref": "MONDO:0004995",
            "name": "cardiovascular disorder"
          },
          {
            "ref": "MONDO:0005151",
            "name": "endocrine system disorder"
          }
        ],
        "definition": "A malignant vascular neoplasm arising from the liver."
      },
      "child_count": 0,
      "reference_id": "MONDO:0002387"
    },
    {
      "id": 4863,
      "label": "liver rhabdomyosarcoma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        4487,
        6928
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:4047",
          "GARD:0023267",
          "MEDGEN:232598",
          "NCIT:C5834",
          "UMLS:C1333975"
        ],
        "synonyms": [
          "hepatic rhabdomyosarcoma",
          "liver rhabdomyosarcoma",
          "liver rhabdomyosarcoma (disease)",
          "rhabdomyosarcoma (disease) of liver",
          "rhabdomyosarcoma of liver",
          "rhabdomyosarcoma of the liver"
        ],
        "categories": [
          {
            "ref": "MONDO:0004335",
            "name": "digestive system disorder"
          },
          {
            "ref": "MONDO:0005151",
            "name": "endocrine system disorder"
          }
        ],
        "definition": "A malignant mesenchymal tumor with skeletal muscle differentiation affecting the liver."
      },
      "child_count": 2,
      "reference_id": "MONDO:0002849"
    },
    {
      "id": 4876,
      "label": "bile duct sarcoma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        4487,
        5049
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:4064",
          "GARD:0023279"
        ],
        "synonyms": [
          "bile duct sarcoma",
          "sarcoma of bile duct"
        ],
        "categories": [
          {
            "ref": "MONDO:0004335",
            "name": "digestive system disorder"
          },
          {
            "ref": "MONDO:0005151",
            "name": "endocrine system disorder"
          }
        ],
        "definition": "A sarcoma that involves the bile duct."
      },
      "child_count": 2,
      "reference_id": "MONDO:0002862"
    },
    {
      "id": 5312,
      "label": "liver leiomyosarcoma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        4487,
        6788
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:5296",
          "GARD:0023490",
          "MEDGEN:272707",
          "NCIT:C5756",
          "UMLS:C1333969"
        ],
        "synonyms": [
          "hepatic leiomyosarcoma",
          "leiomyosarcoma of liver",
          "leiomyosarcoma of the liver",
          "liver leiomyosarcoma"
        ],
        "categories": [
          {
            "ref": "MONDO:0002081",
            "name": "musculoskeletal system disorder"
          },
          {
            "ref": "MONDO:0004335",
            "name": "digestive system disorder"
          },
          {
            "ref": "MONDO:0005151",
            "name": "endocrine system disorder"
          }
        ],
        "definition": "An aggressive malignant smooth muscle neoplasm, arising from the liver. It is characterized by a proliferation of neoplastic spindle cells."
      },
      "child_count": 2,
      "reference_id": "MONDO:0003378"
    },
    {
      "id": 5731,
      "label": "liver extraskeletal osteosarcoma",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        4487,
        4672
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:6370",
          "GARD:0023705",
          "MEDGEN:232597",
          "NCIT:C5833",
          "UMLS:C1333974"
        ],
        "synonyms": [
          "hepatic extraskeletal osteosarcoma",
          "hepatic osteogenic sarcoma",
          "hepatic osteosarcoma",
          "liver extraskeletal osteosarcoma",
          "liver osteogenic sarcoma",
          "liver osteosarcoma",
          "liver osteosarcoma (disease)",
          "osteogenic sarcoma of liver",
          "osteogenic sarcoma of the liver",
          "osteosarcoma of liver",
          "osteosarcoma of the liver"
        ],
        "categories": [
          {
            "ref": "MONDO:0004335",
            "name": "digestive system disorder"
          },
          {
            "ref": "MONDO:0005151",
            "name": "endocrine system disorder"
          }
        ],
        "definition": "An osteosarcoma arising from the liver."
      },
      "child_count": 0,
      "reference_id": "MONDO:0003866"
    },
    {
      "id": 6242,
      "label": "liver fibrosarcoma",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        4487,
        6886
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:8022",
          "GARD:0024003",
          "MEDGEN:232274",
          "NCIT:C5832",
          "UMLS:C1333966"
        ],
        "synonyms": [
          "fibrosarcoma of liver",
          "fibrosarcoma of the liver",
          "hepatic fibrosarcoma",
          "liver fibrosarcoma",
          "liver fibrosarcoma (disease)"
        ],
        "categories": [
          {
            "ref": "MONDO:0003900",
            "name": "connective tissue disorder"
          },
          {
            "ref": "MONDO:0004335",
            "name": "digestive system disorder"
          },
          {
            "ref": "MONDO:0005151",
            "name": "endocrine system disorder"
          }
        ],
        "definition": "A usually aggressive malignant neoplasm arising from the liver. It is characterized by the presence of spindle-shaped fibroblasts and collagenous stroma formation in a herringbone growth pattern."
      },
      "child_count": 0,
      "reference_id": "MONDO:0004435"
    },
    {
      "id": 6829,
      "label": "undifferentiated (embryonal) sarcoma",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        4487
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "EFO:0000730",
          "GARD:0008650",
          "ICDO:8805/3",
          "ICDO:8991/3",
          "MEDGEN:163512",
          "NANDO:2200058",
          "NCIT:C27096",
          "UMLS:C0855073"
        ],
        "synonyms": [
          "UES",
          "embryonal sarcoma",
          "embryonal sarcoma (undifferentiated sarcoma)",
          "embryonal sarcoma, undifferentiated",
          "sarcoma, undifferentiated, malignant",
          "undifferentiated (embryonal) sarcoma",
          "undifferentiated sarcoma"
        ],
        "categories": [
          {
            "ref": "MONDO:0004335",
            "name": "digestive system disorder"
          },
          {
            "ref": "MONDO:0005151",
            "name": "endocrine system disorder"
          }
        ],
        "definition": "An aggressive malignant mesenchymal neoplasm that arises from the liver and usually occurs in older children. It is composed of immature spindle, stellate, polymorphous, and giant cells."
      },
      "child_count": 0,
      "reference_id": "MONDO:0005102"
    }
  ],
  "roots": [
    {
      "id": 4735,
      "label": "liver cancer"
    },
    {
      "id": 18239,
      "label": "soft tissue sarcoma"
    }
  ]
}