{
  "id": 4488,
  "label": "mucinous adenofibroma",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0002398",
  "properties": {
    "xrefs": [
      "DOID:2700",
      "ICDO:9015/0",
      "MEDGEN:83158",
      "NCIT:C8978",
      "UMLS:C0334499"
    ],
    "synonyms": [
      "mucinous adenofibroma"
    ],
    "categories": [
      {
        "ref": "MONDO:0003900",
        "name": "connective tissue disorder"
      },
      {
        "ref": "MONDO:0005039",
        "name": "reproductive system disorder"
      }
    ],
    "definition": "A benign adenofibroma characterized by the presence of epithelial cells which contain intracytoplasmic mucin and a fibrotic stroma. A representative example is the ovarian mucinous adenofibroma. Cases with epithelial atypia described in the ovary lacking stromal invasion are designated as borderline mucinous adenofibromas and have a low grade malignant potential."
  },
  "isLeaf": false,
  "isRoot": false,
  "child_count": 2,
  "parents": [
    {
      "id": 7650,
      "label": "adenofibroma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        3029,
        6889
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:2683",
          "EFO:1000070",
          "ICDO:9013/0",
          "MEDGEN:1325",
          "MESH:D000232",
          "NCIT:C8984",
          "UMLS:C0001422"
        ],
        "synonyms": [
          "adenofibroma, benign",
          "adenofibroma, no ICD-O subtype",
          "adenofibroma, no ICD-O subtype (morphologic abnormality)",
          "benign mixed Muellerian tumor",
          "benign mixed Muellerian tumour",
          "female reproductive system adenofibroma"
        ],
        "categories": [
          {
            "ref": "MONDO:0003900",
            "name": "connective tissue disorder"
          },
          {
            "ref": "MONDO:0005039",
            "name": "reproductive system disorder"
          }
        ],
        "definition": "A benign neoplasm characterized by the presence of connective tissue stroma and epithelial structures. It occurs in the ovary, fallopian tube, uterine corpus, and cervix. Cases of adenofibroma of the ovary with low grade malignant potential have also been reported."
      },
      "child_count": 12,
      "reference_id": "MONDO:0006071"
    },
    {
      "id": 21367,
      "label": "mucinous neoplasm",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        21312
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "MEDGEN:235339",
          "NCIT:C7070",
          "UMLS:C1334811"
        ],
        "synonyms": [
          "mucinous neoplasm",
          "mucinous tumor",
          "mucinous tumour"
        ]
      },
      "child_count": 5,
      "reference_id": "MONDO:0024338"
    },
    {
      "id": 22952,
      "label": "benign epithelial neoplasm",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6887,
        7265
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "ICDO:8010/0",
          "ICDO:8011/0",
          "MEDGEN:90747",
          "NCIT:C4092",
          "UMLS:C0334232"
        ],
        "synonyms": [
          "benign epithelial neoplasm",
          "benign epithelial tumor",
          "benign epithelial tumour",
          "benign epithelioma",
          "benign neoplasm of epithelium",
          "benign neoplasm of the epithelium",
          "benign tumor of epithelium",
          "benign tumor of the epithelium",
          "benign tumour of epithelium",
          "benign tumour of the epithelium",
          "epithelial neoplasm, benign",
          "epithelioma, benign"
        ],
        "definition": "A neoplasm arising from the epithelial cells. It is characterized by the absence of morphologic features associated with malignancy (severe cytologic atypia, tumor cell necrosis, and high mitotic rate). Benign epithelial neoplasms remain confined to the original site of growth and only rarely metastasize to other anatomic sites."
      },
      "child_count": 50,
      "reference_id": "MONDO:0036976"
    }
  ],
  "children": [
    {
      "id": 5748,
      "label": "mucinous cystadenofibroma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        4488,
        5386
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:6468",
          "MEDGEN:234608",
          "NCIT:C8979",
          "UMLS:C1377844"
        ],
        "synonyms": [
          "mucinous cystadenofibroma"
        ],
        "categories": [
          {
            "ref": "MONDO:0003900",
            "name": "connective tissue disorder"
          },
          {
            "ref": "MONDO:0005039",
            "name": "reproductive system disorder"
          }
        ],
        "definition": "A benign neoplasm characterized by the presence of cystic structures lined by mucinous columnar epithelial cells in a fibrotic stroma."
      },
      "child_count": 2,
      "reference_id": "MONDO:0003886"
    },
    {
      "id": 5749,
      "label": "ovarian mucinous adenofibroma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        3047,
        4347,
        4488
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:6469",
          "MEDGEN:309511",
          "NCIT:C40040",
          "UMLS:C1518723"
        ],
        "synonyms": [
          "mucinous adenofibroma of ovary",
          "ovarian mucinous adenofibroma",
          "ovary mucinous adenofibroma"
        ],
        "categories": [
          {
            "ref": "MONDO:0003900",
            "name": "connective tissue disorder"
          },
          {
            "ref": "MONDO:0005039",
            "name": "reproductive system disorder"
          },
          {
            "ref": "MONDO:0005151",
            "name": "endocrine system disorder"
          }
        ],
        "definition": "A benign neoplasm of the ovary characterized by the presence of glands with mucinous columnar epithelial cells in a fibrotic stroma."
      },
      "child_count": 3,
      "reference_id": "MONDO:0003887"
    }
  ],
  "roots": [
    {
      "id": 7650,
      "label": "adenofibroma"
    },
    {
      "id": 21367,
      "label": "mucinous neoplasm"
    },
    {
      "id": 22952,
      "label": "benign epithelial neoplasm"
    }
  ]
}