{
  "id": 4489,
  "label": "tenosynovial giant cell tumor, localized type",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0002399",
  "properties": {
    "xrefs": [
      "DOID:2701",
      "ICD9:727.02",
      "MEDGEN:154413",
      "NCIT:C6532",
      "SCTID:95413004",
      "UMLS:C0588125"
    ],
    "synonyms": [
      "localised giant cell neoplasm of Tenosynovium",
      "localised giant cell neoplasm of tendon sheath",
      "localised giant cell neoplasm of the Tenosynovium",
      "localised giant cell tumour of Tenosynovium",
      "localised giant cell tumour of tendon sheath",
      "localised giant cell tumour of the Tenosynovium",
      "localised tenosynovial giant cell neoplasm",
      "localised tenosynovial giant cell tumour",
      "localized giant cell neoplasm of Tenosynovium",
      "localized giant cell neoplasm of tendon sheath",
      "localized giant cell neoplasm of the Tenosynovium",
      "localized giant cell tumor of Tenosynovium",
      "localized giant cell tumor of tendon sheath",
      "localized giant cell tumor of the Tenosynovium",
      "localized tenosynovial giant cell neoplasm",
      "localized tenosynovial giant cell tumor",
      "nodular tenosynovitis",
      "synovioma, benign (morphologic abnormality)",
      "tenosynovial giant cell tumor, localized type",
      "benign synovioma",
      "benign tumor of synovium",
      "benign tumour of synovium"
    ],
    "categories": [
      {
        "ref": "MONDO:0002081",
        "name": "musculoskeletal system disorder"
      },
      {
        "ref": "MONDO:0003900",
        "name": "connective tissue disorder"
      }
    ],
    "definition": "A well-circumscribed, lobulated tumor, completely or partially covered by a fibrous capsule. It usually arises in the fingers. It is characterized by the presence of mononuclear cells, multinucleated osteoclast-like giant cells, hemosiderin-laden macrophages, foam cells, and an inflammatory infiltrate. The tumor is slow-growing, usually developing over several years. Clinical presentation includes painless edema of the affected site."
  },
  "isLeaf": true,
  "isRoot": false,
  "child_count": 0,
  "parents": [
    {
      "id": 4592,
      "label": "tenosynovial giant cell tumor",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        4297,
        4597,
        20678,
        21600
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:314",
          "EFO:1000562",
          "ICD9:727.89",
          "ICDO:9252/0",
          "MEDGEN:232927",
          "NCIT:C3402",
          "SCTID:310605004",
          "UMLS:C1318543"
        ],
        "synonyms": [
          "fibrous histiocytoma of tendon sheath",
          "giant cell neoplasm of Tenosynovium",
          "giant cell neoplasm of tendon sheath",
          "giant cell neoplasm of the Tenosynovium",
          "giant cell tumor of Tenosynovium",
          "giant cell tumor of tendon sheath",
          "giant cell tumor of the Tenosynovium",
          "giant cell tumour of the Tenosynovium",
          "tendon sheath giant cell neoplasm",
          "tendon sheath giant cell tumor",
          "tendon sheath giant cell tumour",
          "tenosynovial giant cell neoplasm",
          "tenosynovial giant cell tumor"
        ],
        "categories": [
          {
            "ref": "MONDO:0002081",
            "name": "musculoskeletal system disorder"
          },
          {
            "ref": "MONDO:0003900",
            "name": "connective tissue disorder"
          }
        ],
        "definition": "A tumor usually arising in the synovium of joints, bursa or tendon sheath. It is characterized by the presence of mononuclear cells, multinucleated osteoclast-like giant cells, hemosiderin-laden macrophages, foam cells, and an inflammatory infiltrate. According to the growth pattern, it is classified as localized or diffuse."
      },
      "child_count": 12,
      "reference_id": "MONDO:0002522"
    },
    {
      "id": 21582,
      "label": "benign synovial neoplasm",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        4597,
        23337
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "ICDO:9040/0",
          "MEDGEN:113161",
          "NCIT:C3829",
          "UMLS:C0221289"
        ],
        "synonyms": [
          "benign neoplasm of synovium",
          "benign neoplasm of the synovium",
          "benign synovial neoplasm",
          "benign synovial tumor",
          "benign synovial tumour",
          "benign synovioma",
          "benign synovium neoplasm",
          "benign tumor of synovium",
          "benign tumor of the synovium",
          "benign tumour of synovium",
          "benign tumour of the synovium",
          "synovioma, benign",
          "synovium neoplasm, benign"
        ],
        "categories": [
          {
            "ref": "MONDO:0002081",
            "name": "musculoskeletal system disorder"
          },
          {
            "ref": "MONDO:0003900",
            "name": "connective tissue disorder"
          }
        ],
        "definition": "A benign neoplasm arising from the synovial membrane. Examples include the diffuse giant cell tumor of tendon sheath and localized giant cell tumor of tendon sheath."
      },
      "child_count": 8,
      "reference_id": "MONDO:0024715"
    }
  ],
  "children": [],
  "roots": [
    {
      "id": 4592,
      "label": "tenosynovial giant cell tumor"
    },
    {
      "id": 21582,
      "label": "benign synovial neoplasm"
    }
  ]
}