{
  "id": 4517,
  "label": "idiopathic interstitial pneumonia",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0002429",
  "properties": {
    "xrefs": [
      "DOID:2797",
      "GARD:0013337",
      "ICD10CM:J84.11",
      "MEDGEN:389939",
      "MESH:D054988",
      "NANDO:1200416",
      "NANDO:2200199",
      "NCIT:C35714",
      "Orphanet:98300",
      "SCTID:700249006",
      "UMLS:C2350236"
    ],
    "synonyms": [
      "IIP",
      "IIp",
      "idiopathic fibrosing alveolitis",
      "idiopathic interstitial pneumonitis",
      "noninfectious pneumonia"
    ],
    "categories": [
      {
        "ref": "MONDO:0005087",
        "name": "respiratory system disorder"
      }
    ],
    "definition": "A class of diffuse lung diseases that typically affect the pulmonary interstitium, although some also have a component affecting the airways (for instance, Cryptogenic organizing pneumonitis)."
  },
  "isLeaf": false,
  "isRoot": false,
  "child_count": 10,
  "parents": [
    {
      "id": 6953,
      "label": "pneumonia",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        21378,
        23261
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:552",
          "EFO:0003106",
          "ICD10CM:J15",
          "ICD10CM:J18.9",
          "ICD9:483",
          "ICD9:483.8",
          "ICD9:484.8",
          "ICD9:486",
          "MEDGEN:10813",
          "MESH:D011014",
          "NCIT:C3333",
          "SCTID:233604007",
          "UMLS:C0032285",
          "icd11.foundation:142052508"
        ],
        "synonyms": [
          "acute pneumonia"
        ],
        "categories": [
          {
            "ref": "MONDO:0005087",
            "name": "respiratory system disorder"
          }
        ],
        "definition": "An acute, acute and chronic, or chronic inflammation focally or diffusely affecting the lung parenchyma, caused by an infection in one or both of the lungs (by bacteria, viruses, fungi, or mycoplasma.). Symptoms include cough, shortness of breath, fevers, chills, chest pain, headache, sweating, and weakness."
      },
      "child_count": 22,
      "reference_id": "MONDO:0005249"
    },
    {
      "id": 24405,
      "label": "idiopathic disease",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        29381
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "MEDGEN:548250",
          "UMLS:C0277553"
        ],
        "synonyms": [
          "idiopathic disorder"
        ],
        "definition": "A disease or disorder for which the cause is of uncertain or unknown."
      },
      "child_count": 79,
      "reference_id": "MONDO:0700007"
    }
  ],
  "children": [
    {
      "id": 10759,
      "label": "lymphoid interstitial pneumonia",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        4517
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0050159",
          "GARD:0016700",
          "ICD10CM:J84.2",
          "ICD9:516.8",
          "MEDGEN:82682",
          "MESH:C562489",
          "MedDRA:10062997",
          "NANDO:1200424",
          "NCIT:C27558",
          "OMIM:247610",
          "Orphanet:79128",
          "SCTID:44274007",
          "UMLS:C0264511",
          "icd11.foundation:1140418798"
        ],
        "synonyms": [
          "diffuse hyperplasia of bronchus-associated lymphoid tissue",
          "lymphocytic interst. pneumonitis",
          "lymphocytic interstitial pneumonia",
          "lymphocytic interstitial pneumonitis",
          "lymphoid interstitial pneumonia",
          "LIP"
        ],
        "categories": [
          {
            "ref": "MONDO:0005087",
            "name": "respiratory system disorder"
          }
        ],
        "definition": "Interstitial pneumonia characterized by the presence of bibasilar pulmonary interstitial infiltrates composed of lymphocytes and plasma cells. It may be associated with autoimmune and lymphoproliferative disorders. Signs and symptoms include fever, cough, and dyspnea. Symptomatic patients may require immunosuppressive treatment."
      },
      "child_count": 0,
      "reference_id": "MONDO:0009537"
    },
    {
      "id": 11090,
      "label": "desquamative interstitial pneumonia",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        4517
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0050158",
          "GARD:0016864",
          "ICD10CM:J84.117",
          "ICD9:516.34",
          "ICD9:516.37",
          "MEDGEN:65962",
          "MESH:C562470",
          "NANDO:1200422",
          "NANDO:1200423",
          "NCIT:C35288",
          "OMIM:263000",
          "Orphanet:98852",
          "SCTID:8549006",
          "UMLS:C0238378",
          "icd11.foundation:1620001155"
        ],
        "synonyms": [
          "RBILD",
          "desquamative interstitial pneumonia",
          "respiratory bronchiolitis interstitial lung disease",
          "DIP",
          "ILD, desquamative",
          "interstitial lung disease, desquamative",
          "interstitial pneumonitis, desquamative, familial",
          "pneumonia, desquamative interstitial, familial",
          "pneumonitis, desquamative interstitial, familial"
        ],
        "categories": [
          {
            "ref": "MONDO:0005087",
            "name": "respiratory system disorder"
          }
        ],
        "definition": "A rare idiopathic interstitial pneumonia characterized by accumulation of macrophages in alveolar spaces and interstitial inflammation. It usually occurs in smokers. Some patients develop progressive interstitial lung fibrosis."
      },
      "child_count": 0,
      "reference_id": "MONDO:0009887"
    },
    {
      "id": 16148,
      "label": "cryptogenic organizing pneumonia",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        4517
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0050157",
          "EFO:1001300",
          "GARD:0001620",
          "ICD10CM:J84.116",
          "ICD9:516.36",
          "MEDGEN:116663",
          "MESH:D018549",
          "NANDO:1200421",
          "NCIT:C62586",
          "NORD:873",
          "Orphanet:1302",
          "SCTID:68409003",
          "SCTID:719218000",
          "UMLS:C0242770",
          "icd11.foundation:1937662238"
        ],
        "synonyms": [
          "COP",
          "Organizing Pneumonia",
          "bronchiolitis obliterans organizing pneumonia",
          "cryptogenic organizing pneumonitis",
          "organising pneumonia",
          "organizing pneumonia",
          "constrictive bronchiolitis",
          "idiopathic BOOP",
          "idiopathic bronchiolitis obliterans organising pneumonia",
          "idiopathic bronchiolitis obliterans organizing pneumonia"
        ],
        "categories": [
          {
            "ref": "MONDO:0005087",
            "name": "respiratory system disorder"
          }
        ],
        "definition": "Cryptogenic organizing pneumonia (COP) is a form of idiopathic interstitial pneumonia characterized pathologically by organizing pneumonia (OP) that presents with non-specific flu-like symptoms, as well as cough and dyspnea and where no etiological agent is found."
      },
      "child_count": 0,
      "reference_id": "MONDO:0015264"
    },
    {
      "id": 17871,
      "label": "combined pulmonary fibrosis-emphysema syndrome",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        4517
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0021238",
          "MEDGEN:838971",
          "Orphanet:300564",
          "UMLS:C3872815",
          "icd11.foundation:1361267223"
        ],
        "synonyms": [
          "CPFE"
        ],
        "categories": [
          {
            "ref": "MONDO:0005087",
            "name": "respiratory system disorder"
          }
        ]
      },
      "child_count": 0,
      "reference_id": "MONDO:0017591"
    },
    {
      "id": 19073,
      "label": "acute interstitial pneumonia",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        4517,
        20092
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:2800",
          "GARD:0012835",
          "ICD10CM:J84.114",
          "ICD9:516.33",
          "MEDGEN:39340",
          "MedDRA:10066728",
          "NANDO:1200420",
          "NCIT:C35806",
          "Orphanet:79126",
          "SCTID:236302005",
          "UMLS:C0085786",
          "icd11.foundation:2116884221"
        ],
        "synonyms": [
          "AIP",
          "Hamman-rich syndrome",
          "acute interstitial pneumonitis"
        ],
        "categories": [
          {
            "ref": "MONDO:0005087",
            "name": "respiratory system disorder"
          }
        ],
        "definition": "Acute interstitial pneumonia (AIP), also referred to as Hamman-Rich syndrome, is a rapidly progressive and histologically distinct form of idiopathic interstitial pneumonia."
      },
      "child_count": 0,
      "reference_id": "MONDO:0019203"
    },
    {
      "id": 19074,
      "label": "respiratory bronchiolitis-interstitial lung disease syndrome",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        4517
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0018942",
          "MEDGEN:1672485",
          "MedDRA:10066393",
          "Orphanet:79127",
          "UMLS:C1735355",
          "icd11.foundation:822500243"
        ],
        "synonyms": [
          "RB-ILD"
        ],
        "categories": [
          {
            "ref": "MONDO:0005087",
            "name": "respiratory system disorder"
          }
        ],
        "definition": "Respiratory bronchiolitis - interstitial lung disease is a mild inflammatory pulmonary disorder developed by cigarette smokers and characterized by shortness of breath and cough, pulmonary function abnormalities of mixed restrictive and obstructive lung disease and high resolution CT scanning showing centrilobular micronodules, ground glass opacities and peribronchiolar thickening."
      },
      "child_count": 0,
      "reference_id": "MONDO:0019204"
    },
    {
      "id": 19412,
      "label": "non-specific interstitial pneumonia",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        4517
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:2801",
          "GARD:0019167",
          "ICD9:516.8",
          "MEDGEN:220936",
          "NANDO:1200419",
          "NCIT:C35717",
          "Orphanet:91364",
          "SCTID:129452008",
          "UMLS:C1290344"
        ],
        "synonyms": [
          "NSIP",
          "non-specific idiopathic interstitial pneumonia",
          "nonspecific interstitial pneumonia"
        ],
        "categories": [
          {
            "ref": "MONDO:0005087",
            "name": "respiratory system disorder"
          }
        ],
        "definition": "Idiopathic interstitial pneumonia characterized by chronic inflammation and fibrosis in the interstitial lung tissue. It includes cases that cannot be classified into one of the other types of idiopathic interstitial pneumonia."
      },
      "child_count": 0,
      "reference_id": "MONDO:0019622"
    },
    {
      "id": 23366,
      "label": "idiopathic pleuroparenchymal fibroelastosis",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        4517
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0022004",
          "MEDGEN:1798890",
          "Orphanet:494428",
          "UMLS:C5567467"
        ],
        "synonyms": [
          "IPPFE",
          "idiopathic pleuropulmonary fibroelastosis"
        ],
        "categories": [
          {
            "ref": "MONDO:0005087",
            "name": "respiratory system disorder"
          }
        ]
      },
      "child_count": 0,
      "reference_id": "MONDO:0044633"
    },
    {
      "id": 24823,
      "label": "follicular bronchiolits",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        4517
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0026440"
        ],
        "categories": [
          {
            "ref": "MONDO:0005087",
            "name": "respiratory system disorder"
          }
        ],
        "definition": "A polyclonal hyperplasia of bronchiolar associated lymphoid tissue characterized by the development of lymphoid follicles with germinal centers in walls of the small airways."
      },
      "child_count": 0,
      "reference_id": "MONDO:0800114"
    },
    {
      "id": 25088,
      "label": "idiopathic pulmonary fibrosis",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        4517,
        16615
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0050156",
          "GARD:0028067",
          "ICD10CM:J84.112",
          "MEDGEN:321462",
          "MESH:D054990",
          "NCIT:C35716",
          "Orphanet:2032",
          "UMLS:C1800706",
          "icd11.foundation:1074069640"
        ],
        "synonyms": [
          "IPF"
        ],
        "categories": [
          {
            "ref": "MONDO:0005087",
            "name": "respiratory system disorder"
          }
        ],
        "definition": "An interstitial lung disease with a poor prognosis, that is characterized by the progressive formation of scar tissue within the lungs in the absence of any known cause."
      },
      "child_count": 0,
      "reference_id": "MONDO:0800504"
    }
  ],
  "roots": [
    {
      "id": 6953,
      "label": "pneumonia"
    },
    {
      "id": 24405,
      "label": "idiopathic disease"
    }
  ]
}