{
  "id": 4541,
  "label": "membranoproliferative glomerulonephritis",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0002461",
  "properties": {
    "xrefs": [
      "DOID:2920",
      "GARD:0023141",
      "HP:0000793",
      "MEDGEN:9033",
      "MESH:D015432",
      "NANDO:1200737",
      "NANDO:2200123",
      "NCIT:C34644",
      "SCTID:80321008",
      "UMLS:C0017662"
    ],
    "synonyms": [
      "membranoproliferative glomerulonephritis",
      "membranoproliferative glomerulonephritis (disease)"
    ],
    "categories": [
      {
        "ref": "MONDO:0002118",
        "name": "urinary system disorder"
      }
    ],
    "definition": "Inflammation of the glomeruli characterized by deposits at the intraglomerular mesangium, resulting in thickening of the glomerular basement membrane, activation of complement, and impaired kidney function secondary to damaged glomeruli."
  },
  "isLeaf": true,
  "isRoot": false,
  "child_count": 0,
  "parents": [
    {
      "id": 4542,
      "label": "glomerulonephritis",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        3410,
        19482
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:2921",
          "GARD:0006516",
          "HP:0000099",
          "ICD9:583.9",
          "MEDGEN:6616",
          "MESH:D005921",
          "NCIT:C26784",
          "SCTID:36171008",
          "UMLS:C0017658"
        ],
        "synonyms": [
          "glomerular nephritis",
          "glomerulonephritis",
          "glomerulonephritis (disease)",
          "nephritis of renal glomerulus",
          "renal glomerulus nephritis",
          "bright's disease"
        ],
        "categories": [
          {
            "ref": "MONDO:0002118",
            "name": "urinary system disorder"
          }
        ],
        "definition": "A renal disorder characterized by damage in the glomeruli. It may be acute or chronic, focal or diffuse, and it may lead to renal failure. Causes include autoimmune disorders, infections, diabetes, and malignancies."
      },
      "child_count": 40,
      "reference_id": "MONDO:0002462"
    }
  ],
  "children": [],
  "roots": [
    {
      "id": 4542,
      "label": "glomerulonephritis"
    }
  ]
}