{
  "id": 4553,
  "label": "cystic kidney disease",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0002473",
  "properties": {
    "xrefs": [
      "DOID:2975",
      "EFO:0008615",
      "ICD10CM:Q61",
      "ICD10WHO:Q61",
      "MEDGEN:854361",
      "MESH:D052177",
      "NANDO:2200172",
      "NCIT:C34750",
      "SCTID:722223000",
      "UMLS:C3887499"
    ],
    "synonyms": [
      "cystic renal disease",
      "kidney cyst"
    ],
    "categories": [
      {
        "ref": "MONDO:0002118",
        "name": "urinary system disorder"
      }
    ],
    "definition": "A congenital or acquired kidney disorder characterized by the presence of renal cysts."
  },
  "isLeaf": false,
  "isRoot": false,
  "child_count": 4,
  "parents": [
    {
      "id": 6948,
      "label": "kidney disorder",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        4253
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:557",
          "EFO:0003086",
          "ICD9:583.81",
          "MEDGEN:9635",
          "MESH:D007674",
          "NCIT:C3149",
          "SCTID:90708001",
          "UMLS:C0022658"
        ],
        "synonyms": [
          "disease of kidney",
          "disease or disorder of kidney",
          "disorder of kidney",
          "kidney disease",
          "kidney disease or disorder",
          "kidney disorder",
          "renal disease",
          "renal disorder",
          "nephropathy"
        ],
        "categories": [
          {
            "ref": "MONDO:0002118",
            "name": "urinary system disorder"
          }
        ],
        "definition": "A disease involving the kidney."
      },
      "child_count": 57,
      "reference_id": "MONDO:0005240"
    }
  ],
  "children": [
    {
      "id": 6597,
      "label": "non-congenital cyst of kidney",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        4553
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:9621",
          "ICD9:593.2",
          "MEDGEN:541491",
          "SCTID:105999006",
          "UMLS:C0268799"
        ],
        "categories": [
          {
            "ref": "MONDO:0002118",
            "name": "urinary system disorder"
          }
        ]
      },
      "child_count": 0,
      "reference_id": "MONDO:0004840"
    },
    {
      "id": 16151,
      "label": "medullary sponge kidney",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        4553,
        20383
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0000232",
          "ICD9:753.17",
          "MEDGEN:5970",
          "MESH:D007691",
          "MedDRA:10027104",
          "NANDO:2200173",
          "NCIT:C34751",
          "NORD:1421",
          "Orphanet:1309",
          "SCTID:236443009",
          "UMLS:C0022681",
          "icd11.foundation:1723148250"
        ],
        "synonyms": [
          "Cacchi-Ricci disease",
          "MSK",
          "Precalicial canalicular ectasia",
          "Cacchi Ricci disease",
          "Cacchi-Ricci syndrome",
          "Precalyceal canalicular ectasia",
          "cystic dilatation of renal collecting tubes",
          "sponge kidney"
        ],
        "categories": [
          {
            "ref": "MONDO:0002118",
            "name": "urinary system disorder"
          }
        ],
        "definition": "Medullary sponge kidney (MSK) is a birth defect of the tubules - tiny tubes inside the kidneys. In a normal kidney, urine flows through these tubules as it is being formed. In MSK, tiny sacs called cysts form in the medulla (the inner part of the kidney), creating a sponge-like appearance. The cysts keep urine from flowing freely through the tubules. MSK is present at birth but symptoms typically do not occur until adolescence or adulthood. Problems caused by MSK include blood in the urine, kidney stones, and urinary tract infections. MSK rarely leads to more serious problems, such as total kidney failure. There is no cure for this condition, so treatment is aimed at removing kidney stones and treating urinary tract infections with antibiotics."
      },
      "child_count": 0,
      "reference_id": "MONDO:0015268"
    },
    {
      "id": 16633,
      "label": "multicystic dysplastic kidney",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        4553,
        20383
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0018748",
          "ICD9:753.19",
          "MEDGEN:811388",
          "MESH:D021782",
          "NANDO:2200158",
          "NCIT:C123031",
          "Orphanet:1851",
          "SCTID:204962002",
          "UMLS:C3714581",
          "icd11.foundation:1178642763"
        ],
        "synonyms": [
          "MCDK",
          "multicystic renal dysplasia"
        ],
        "categories": [
          {
            "ref": "MONDO:0002118",
            "name": "urinary system disorder"
          }
        ],
        "definition": "Multicystic dysplastic kidney (MCDK) is a congenital anomaly of the kidney and urinary tract (CAKUT) in which one or both kidneys (unilateral or bilateral MCDK respectively) are large, distended by multiple cysts, and non-functional."
      },
      "child_count": 4,
      "reference_id": "MONDO:0015988"
    },
    {
      "id": 19499,
      "label": "familial cystic renal disease",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        4553,
        23932
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0019228",
          "MEDGEN:1842297",
          "Orphanet:93587",
          "UMLS:C5680285"
        ],
        "synonyms": [
          "hereditary cystic kidney disease"
        ],
        "categories": [
          {
            "ref": "MONDO:0002118",
            "name": "urinary system disorder"
          }
        ],
        "definition": "An instance of cystic kidney disease that is caused by an inherited modification of the individual's genome."
      },
      "child_count": 8,
      "reference_id": "MONDO:0019741"
    }
  ],
  "roots": [
    {
      "id": 6948,
      "label": "kidney disorder"
    }
  ]
}