{
  "id": 4563,
  "label": "breast myoepithelial tumor",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0002483",
  "properties": {
    "xrefs": [
      "DOID:3004",
      "MEDGEN:267411",
      "NCIT:C40389",
      "UMLS:C1511319"
    ],
    "synonyms": [
      "breast myoepithelial neoplasm",
      "breast myoepithelial tumor"
    ],
    "categories": [
      {
        "ref": "MONDO:0002657",
        "name": "breast disorder"
      }
    ],
    "definition": "A benign or malignant tumor that arises from the breast and originates from or is composed of myoepithelial cells. Representative examples include adenomyoepithelioma, myoepitheliosis, and malignant myoepithelioma."
  },
  "isLeaf": false,
  "isRoot": false,
  "child_count": 3,
  "parents": [
    {
      "id": 4477,
      "label": "myoepithelial tumor",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        7265
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:2661",
          "ICDO:8982/0",
          "ICDO:8982/1",
          "MEDGEN:10235",
          "MESH:D009208",
          "NCIT:C40392",
          "UMLS:C0027070"
        ],
        "synonyms": [
          "myoepithelial neoplasm",
          "myoepithelial tumor",
          "myoepithelioma",
          "benign myoepithelioma"
        ],
        "definition": "A benign or malignant tumor characterized by the presence of cells that show myoepithelial differentiation. Based on its morphologic features, it is classified as benign or malignant. A representative example of benign myoepithelioma is benign salivary gland myoepithelioma. Representative examples of malignant myoepithelioma or myoepithelial carcinoma are malignant breast myoepithelioma and salivary gland myoepithelial carcinoma."
      },
      "child_count": 4,
      "reference_id": "MONDO:0002380"
    },
    {
      "id": 20340,
      "label": "breast neoplasm",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        4708,
        20518
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "EFO:0003869",
          "ICD9:239.3",
          "MEDGEN:264172",
          "MESH:D001943",
          "NCIT:C2910",
          "ONCOTREE:BREAST",
          "SCTID:126926005",
          "UMLS:C1458155"
        ],
        "synonyms": [
          "breast neoplasm",
          "breast neoplasm (disease)",
          "breast tumor",
          "breast tumour",
          "neoplasm of breast",
          "neoplasm of the breast",
          "neoplasm, breast",
          "tumor of breast",
          "tumor of the breast",
          "tumour of breast",
          "tumour of the breast"
        ],
        "categories": [
          {
            "ref": "MONDO:0002657",
            "name": "breast disorder"
          }
        ],
        "definition": "A benign or malignant neoplasm of the breast parenchyma. It can originate from the ducts, lobules or the breast adipose tissue. Breast neoplasms are much more common in females than males."
      },
      "child_count": 22,
      "reference_id": "MONDO:0021100"
    }
  ],
  "children": [
    {
      "id": 4209,
      "label": "breast adenomyoepithelioma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        4563
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:1642",
          "ICDO:8983/0",
          "MEDGEN:267278",
          "NCIT:C6899",
          "ONCOTREE:BRAME",
          "UMLS:C1510795"
        ],
        "synonyms": [
          "adenomyoepithelioma of the breast",
          "breast adenomyoepithelioma",
          "BRAME"
        ],
        "categories": [
          {
            "ref": "MONDO:0002657",
            "name": "breast disorder"
          }
        ],
        "definition": "A usually benign tumor arising from the breast. It is characterized by the proliferation of cells with myoepithelial differentiation around spaces which are lined by epithelial cells. Rarely, the epithelial and/or myoepithelial cells may undergo malignant transformation. Cases with malignant transformation may follow an aggressive clinical course, including recurrences and local and distant metastases."
      },
      "child_count": 1,
      "reference_id": "MONDO:0002066"
    },
    {
      "id": 5843,
      "label": "malignant breast myoepithelioma",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        4563,
        5127,
        7803
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:6776",
          "GARD:0027662",
          "MEDGEN:309375",
          "NCIT:C40395",
          "UMLS:C1518167"
        ],
        "synonyms": [
          "breast malignant myoepithelioma",
          "breast myoepithelial carcinoma",
          "malignant breast myoepithelioma"
        ],
        "categories": [
          {
            "ref": "MONDO:0002657",
            "name": "breast disorder"
          }
        ],
        "definition": "An invasive malignant tumor that arises from the breast. It is characterized by the presence of spindle-shaped myoepithelial cells. Mitoses are present. Rarely, local recurrences and distant metastases have been reported."
      },
      "child_count": 0,
      "reference_id": "MONDO:0003990"
    },
    {
      "id": 6082,
      "label": "breast myoepitheliosis",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        4563
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:7521",
          "MEDGEN:269362",
          "NCIT:C40385",
          "UMLS:C1513799"
        ],
        "synonyms": [
          "breast myoepitheliosis"
        ],
        "categories": [
          {
            "ref": "MONDO:0002657",
            "name": "breast disorder"
          }
        ],
        "definition": "A multifocal neoplastic process characterized by the proliferation of spindle to cuboidal myoepithelial cells within and/or around small breast ducts."
      },
      "child_count": 2,
      "reference_id": "MONDO:0004262"
    }
  ],
  "roots": [
    {
      "id": 4477,
      "label": "myoepithelial tumor"
    },
    {
      "id": 20340,
      "label": "breast neoplasm"
    }
  ]
}