{
  "id": 4571,
  "label": "acute kidney injury",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0002492",
  "properties": {
    "xrefs": [
      "DOID:3021",
      "ICD10CM:N17",
      "MEDGEN:388570",
      "MESH:D058186",
      "NCIT:C26808",
      "UMLS:C2609414",
      "icd11.foundation:476391827"
    ],
    "synonyms": [
      "AKI",
      "ARF",
      "acute kidney failure",
      "acute renal failure",
      "kidney failure, acute"
    ],
    "categories": [
      {
        "ref": "MONDO:0002118",
        "name": "urinary system disorder"
      }
    ],
    "definition": "Sudden and sustained deterioration of the kidney function characterized by decreased glomerular filtration rate, increased serum creatinine or oliguria."
  },
  "isLeaf": false,
  "isRoot": false,
  "child_count": 1,
  "parents": [
    {
      "id": 3356,
      "label": "kidney failure",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6948
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:1074",
          "EFO:1002048",
          "ICD9:404.12",
          "ICD9:404.13",
          "ICD9:586",
          "MEDGEN:11177",
          "MESH:D051437",
          "NCIT:C4376",
          "SCTID:42399005",
          "UMLS:C0035078",
          "icd11.foundation:761526554"
        ],
        "synonyms": [
          "failure, renal",
          "renal failure",
          "renal failure syndrome",
          "renal insufficiency"
        ],
        "categories": [
          {
            "ref": "MONDO:0002118",
            "name": "urinary system disorder"
          }
        ],
        "definition": "An acute or chronic condition that is characterized by the inability of the kidneys to adequately filter the blood."
      },
      "child_count": 3,
      "reference_id": "MONDO:0001106"
    },
    {
      "id": 20092,
      "label": "acute disease",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        24492
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "ICD9:799.89",
          "MEDGEN:1738",
          "MESH:D000208",
          "SCTID:2704003",
          "UMLS:C0001314"
        ],
        "synonyms": [
          "acute disease",
          "acute diseases",
          "disease, acute"
        ],
        "definition": "Disease having a short and relatively severe course."
      },
      "child_count": 119,
      "reference_id": "MONDO:0020683"
    }
  ],
  "children": [
    {
      "id": 8109,
      "label": "acute kidney tubular necrosis",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        4571
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:12556",
          "EFO:1000794",
          "HP:0008682",
          "ICD10CM:N17.0",
          "ICD9:584.5",
          "MEDGEN:7213",
          "MESH:D007683",
          "MedDRA:10023441",
          "NCIT:C34749",
          "SCTID:35455006",
          "UMLS:C0022672"
        ],
        "synonyms": [
          "acute renal failure with lesion of tubular necrosis",
          "acute renal failure with tubular necrosis",
          "acute tubular necrosis"
        ],
        "categories": [
          {
            "ref": "MONDO:0002118",
            "name": "urinary system disorder"
          }
        ],
        "definition": "Acute renal failure caused by the cell death of the renal tubules. Causes include nephrotoxins, cytotoxic drugs, and antibiotics."
      },
      "child_count": 0,
      "reference_id": "MONDO:0006637"
    }
  ],
  "roots": [
    {
      "id": 3356,
      "label": "kidney failure"
    },
    {
      "id": 20092,
      "label": "acute disease"
    }
  ]
}