{
  "id": 4572,
  "label": "prostatic acinar adenocarcinoma",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0002493",
  "properties": {
    "xrefs": [
      "DOID:3024",
      "GARD:0027608",
      "MEDGEN:231350",
      "NCIT:C5596",
      "UMLS:C1332139"
    ],
    "synonyms": [
      "acinar adenocarcinoma of prostate",
      "acinar adenocarcinoma of the prostate",
      "acinar prostate adenocarcinoma",
      "prostate acinar adenocarcinoma",
      "prostatic acinar adenocarcinoma"
    ],
    "categories": [
      {
        "ref": "MONDO:0005039",
        "name": "reproductive system disorder"
      }
    ],
    "definition": "An invasive adenocarcinoma of the prostate gland composed of secretory cells. It is the most common histologic type of prostate adenocarcinoma. Several morphologic variants exist, including atrophic, pseudohyperplastic, foamy gland, and oncocytic variants."
  },
  "isLeaf": false,
  "isRoot": false,
  "child_count": 4,
  "parents": [
    {
      "id": 6708,
      "label": "acinar cell carcinoma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6712
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:3025",
          "EFO:0000216",
          "GARD:0008568",
          "ICDO:8550/3",
          "MEDGEN:61660",
          "MESH:D018267",
          "NCIT:C3768",
          "ONCOTREE:ACCC",
          "UMLS:C0206685",
          "icd11.foundation:1322159869"
        ],
        "synonyms": [
          "acinar adenocarcinoma",
          "acinar carcinoma",
          "acinar cell adenocarcinoma",
          "acinar cell carcinoma",
          "acinar cell carcinoma (morphologic abnormality)",
          "acinic cell adenocarcinoma",
          "acinic cell carcinoma",
          "carcinoma of acinar cell",
          "carcinoma, acinar cell, malignant",
          "ACCC",
          "acinic cell tumor",
          "acinic cell tumour"
        ],
        "definition": "A carcinoma that arises from epithelial cells of the acinar cell"
      },
      "child_count": 5,
      "reference_id": "MONDO:0004965"
    },
    {
      "id": 6810,
      "label": "prostate adenocarcinoma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6712,
        6882
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:2526",
          "EFO:0000673",
          "MEDGEN:764",
          "NCIT:C2919",
          "ONCOTREE:PRAD",
          "SCTID:399490008",
          "UMLS:C0007112"
        ],
        "synonyms": [
          "adenocarcinoma of prostate",
          "adenocarcinoma of the prostate",
          "prostate adenocarcinoma",
          "prostate gland adenocarcinoma",
          "prad"
        ],
        "categories": [
          {
            "ref": "MONDO:0005039",
            "name": "reproductive system disorder"
          }
        ],
        "definition": "A carcinoma that arises from glandular epithelial cells of the prostate gland"
      },
      "child_count": 4,
      "reference_id": "MONDO:0005082"
    }
  ],
  "children": [
    {
      "id": 4720,
      "label": "acinar prostate adenocarcinoma, signet ring variant",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        4572,
        6819
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:3504",
          "GARD:0027611",
          "MEDGEN:1835069",
          "NCIT:C5535",
          "UMLS:C5787291"
        ],
        "synonyms": [
          "acinar prostate adenocarcinoma, signet Ring variant",
          "prostate gland signet ring cell carcinoma",
          "signet Ring cell carcinoma of the prostate",
          "prostate signet ring cell adenocarcinoma"
        ],
        "categories": [
          {
            "ref": "MONDO:0005039",
            "name": "reproductive system disorder"
          }
        ],
        "definition": "A morphologic variant of acinar adenocarcinoma of the prostate gland characterized by the presence of signet ring malignant cells."
      },
      "child_count": 0,
      "reference_id": "MONDO:0002672"
    },
    {
      "id": 5989,
      "label": "lymphoepithelioma-like acinar prostate adenocarcinoma",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        4572
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:7246",
          "GARD:0027666",
          "MEDGEN:1834954",
          "NCIT:C39885",
          "UMLS:C5787176"
        ],
        "synonyms": [
          "acinar prostate adenocarcinoma, lymphoepithelioma-like variant"
        ],
        "categories": [
          {
            "ref": "MONDO:0005039",
            "name": "reproductive system disorder"
          }
        ],
        "definition": "A variant of prostate carcinoma characterized by the presence of malignant cells forming syncytial patterns and dense lymphocytic infiltrates."
      },
      "child_count": 0,
      "reference_id": "MONDO:0004164"
    },
    {
      "id": 7646,
      "label": "acinar prostate adenocarcinoma, foamy gland variant",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        4572
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "EFO:1000064",
          "GARD:0027738",
          "MEDGEN:1835068",
          "NCIT:C39882",
          "UMLS:C5787290"
        ],
        "categories": [
          {
            "ref": "MONDO:0005039",
            "name": "reproductive system disorder"
          }
        ],
        "definition": "A variant of acinar prostate adenocarcinoma characterized by the presence of malignant cells with abundant xanthomatous appearing cytoplasm."
      },
      "child_count": 0,
      "reference_id": "MONDO:0006066"
    },
    {
      "id": 7647,
      "label": "acinar prostate mucinous adenocarcinoma",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        4572,
        6700
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:3703",
          "EFO:1000065",
          "GARD:0027739",
          "MEDGEN:277536",
          "NCIT:C5537",
          "UMLS:C1335513"
        ],
        "synonyms": [
          "acinar colloid prostate adenocarcinoma",
          "colloid adenocarcinoma of prostate",
          "colloid adenocarcinoma of the prostate",
          "colloidal adenocarcinoma of prostate",
          "colloidal adenocarcinoma of the prostate",
          "colloidal prostate adenocarcinoma",
          "mucinous adenocarcinoma of prostate",
          "mucinous adenocarcinoma of the prostate",
          "prostate colloid adenocarcinoma"
        ],
        "categories": [
          {
            "ref": "MONDO:0005039",
            "name": "reproductive system disorder"
          }
        ],
        "definition": "A usually aggressive morphologic variant of acinar adenocarcinoma of the prostate gland characterized by the presence of lakes of extracellular mucin. This diagnosis applies when at least 25% of the resected tumor contains extracellular mucin."
      },
      "child_count": 0,
      "reference_id": "MONDO:0006067"
    }
  ],
  "roots": [
    {
      "id": 6708,
      "label": "acinar cell carcinoma"
    },
    {
      "id": 6810,
      "label": "prostate adenocarcinoma"
    }
  ]
}