{
  "id": 4574,
  "label": "colon signet ring cell adenocarcinoma",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0002495",
  "properties": {
    "xrefs": [
      "DOID:3033",
      "MEDGEN:313039",
      "NCIT:C7967",
      "UMLS:C1707436"
    ],
    "synonyms": [
      "colon signet Ring cell adenocarcinoma",
      "colonic signet Ring cell adenocarcinoma",
      "signet Ring cell adenocarcinoma of colon",
      "signet Ring cell adenocarcinoma of the colon",
      "signet Ring cell colon adenocarcinoma",
      "colon signet ring adenocarcinoma"
    ],
    "categories": [
      {
        "ref": "MONDO:0004335",
        "name": "digestive system disorder"
      }
    ],
    "definition": "An invasive adenocarcinoma of the colon characterized by the presence of malignant glandular epithelial cells which contain prominent intracytoplasmic mucin (signet ring cells). The signet ring cells constitute more than 50% of the malignant cells."
  },
  "isLeaf": true,
  "isRoot": false,
  "child_count": 0,
  "parents": [
    {
      "id": 4386,
      "label": "colon adenocarcinoma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        4179,
        6746
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:234",
          "EFO:1001949",
          "MEDGEN:137834",
          "NCIT:C4349",
          "ONCOTREE:COAD",
          "UMLS:C0338106",
          "icd11.foundation:773139368"
        ],
        "synonyms": [
          "adenocarcinoma - colon",
          "adenocarcinoma of colon",
          "adenocarcinoma of the colon",
          "colon adenocarcinoma",
          "colonic adenocarcinoma",
          "COAD"
        ],
        "categories": [
          {
            "ref": "MONDO:0004335",
            "name": "digestive system disorder"
          }
        ],
        "definition": "A carcinoma that arises from glandular epithelial cells of the colon"
      },
      "child_count": 10,
      "reference_id": "MONDO:0002271"
    },
    {
      "id": 23338,
      "label": "colorectal signet ring cell carcinoma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6746,
        6819
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "MEDGEN:313040",
          "NCIT:C43586",
          "UMLS:C1707440"
        ],
        "synonyms": [
          "colorectal signet Ring cell carcinoma"
        ],
        "categories": [
          {
            "ref": "MONDO:0004335",
            "name": "digestive system disorder"
          }
        ],
        "definition": "An invasive colorectal adenocarcinoma characterized by the presence of malignant glandular epithelial cells with prominent intracytoplasmic mucin resulting in the displacement of the nuclei. The malignant glandular cells with intracytoplasmic mucin constitute more than 50% of the malignant cellular infiltrate."
      },
      "child_count": 4,
      "reference_id": "MONDO:0044336"
    }
  ],
  "children": [],
  "roots": [
    {
      "id": 4386,
      "label": "colon adenocarcinoma"
    },
    {
      "id": 23338,
      "label": "colorectal signet ring cell carcinoma"
    }
  ]
}