{
  "id": 4590,
  "label": "anus disorder",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0002519",
  "properties": {
    "xrefs": [
      "DOID:3128",
      "EFO:0009660",
      "MEDGEN:359",
      "MESH:D001004",
      "NCIT:C26695",
      "SCTID:32110003",
      "UMLS:C0003462"
    ],
    "synonyms": [
      "anal disorder",
      "anus disease",
      "anus disease or disorder",
      "disease of anus",
      "disease or disorder of anus",
      "disorder of anal region",
      "disorder of anus",
      "Ulcer of anus",
      "anal fissure",
      "anal fissure and fistula",
      "anal ulcer",
      "fissure in ano",
      "nontraumatic tear of anus",
      "solitary anal ulcer"
    ],
    "categories": [
      {
        "ref": "MONDO:0004335",
        "name": "digestive system disorder"
      }
    ],
    "definition": "A non-neoplastic or neoplastic disorder that affects the anal canal or anal margin. Representative examples of non-neoplastic disorders include hemorrhoids and anal ulcer. Representative examples of neoplastic disorders include carcinoma, lymphoma, and melanoma."
  },
  "isLeaf": false,
  "isRoot": false,
  "child_count": 7,
  "parents": [
    {
      "id": 3792,
      "label": "rectal disorder",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        21545
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:1285",
          "EFO:0009685",
          "ICD9:569.49",
          "MEDGEN:19701",
          "MESH:D012002",
          "SCTID:5964004",
          "UMLS:C0034882"
        ],
        "synonyms": [
          "disease of rectum",
          "disease or disorder of rectum",
          "disorder of rectum",
          "rectal disorder",
          "rectum disease",
          "rectum disease or disorder"
        ],
        "categories": [
          {
            "ref": "MONDO:0004335",
            "name": "digestive system disorder"
          }
        ],
        "definition": "A disease that involves the rectum."
      },
      "child_count": 6,
      "reference_id": "MONDO:0001593"
    }
  ],
  "children": [
    {
      "id": 3303,
      "label": "imperforate anus",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        4590,
        20383
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:10488",
          "GARD:0006769",
          "ICD10CM:Q42.3",
          "MEDGEN:1997",
          "MESH:D001006",
          "NCIT:C84784",
          "NORD:1299",
          "OMIM:207500",
          "OMIM:301800",
          "SCTID:204731006",
          "UMLS:C0003466",
          "icd11.foundation:290678165",
          "icd11.foundation:515168801"
        ],
        "synonyms": [
          "anal atresia",
          "anus, imperforate",
          "congenital atresia of anus",
          "imperforate anus",
          "anal stenosis",
          "anorectal malformations"
        ],
        "categories": [
          {
            "ref": "MONDO:0004335",
            "name": "digestive system disorder"
          }
        ],
        "definition": "A congenital birth defect characterized by the absence of a normal anal opening. It may be associated with other congenital abnormalities."
      },
      "child_count": 0,
      "reference_id": "MONDO:0001046"
    },
    {
      "id": 3421,
      "label": "anorectal stricture",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        4590
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:11014",
          "ICD9:569.2",
          "MEDGEN:57619",
          "SCTID:197216007",
          "UMLS:C0156183"
        ],
        "synonyms": [
          "stenosis of rectum and anus"
        ],
        "categories": [
          {
            "ref": "MONDO:0004335",
            "name": "digestive system disorder"
          }
        ]
      },
      "child_count": 0,
      "reference_id": "MONDO:0001177"
    },
    {
      "id": 3509,
      "label": "anal spasm",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        4590
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:11374",
          "ICD10CM:K59.4",
          "ICD9:564.6",
          "MEDGEN:508910",
          "SCTID:17440005",
          "UMLS:C0152167",
          "icd11.foundation:647005938"
        ],
        "categories": [
          {
            "ref": "MONDO:0004335",
            "name": "digestive system disorder"
          }
        ]
      },
      "child_count": 0,
      "reference_id": "MONDO:0001274"
    },
    {
      "id": 5037,
      "label": "anus neoplasm",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        4291,
        4590
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:4551",
          "EFO:0003835",
          "MEDGEN:360",
          "MESH:D001005",
          "NCIT:C2877",
          "SCTID:126849006",
          "UMLS:C0003463"
        ],
        "synonyms": [
          "anal neoplasm",
          "anal neoplasms, benign and malignant",
          "anal tumor",
          "anal tumors",
          "anal tumour",
          "anal tumours",
          "anus neoplasm",
          "anus neoplasm (disease)",
          "anus tumor",
          "anus tumour",
          "neoplasm of anus",
          "neoplasm of the anus",
          "tumor of anus",
          "tumor of the anus",
          "tumour of anus",
          "tumour of the anus"
        ],
        "categories": [
          {
            "ref": "MONDO:0004335",
            "name": "digestive system disorder"
          }
        ],
        "definition": "A benign or malignant neoplasm that affects the anal canal or anal margin. Representative examples of benign neoplasms include squamous papilloma and papillary hidradenoma. Representative examples of malignant neoplasms include carcinoma, lymphoma, and melanoma."
      },
      "child_count": 6,
      "reference_id": "MONDO:0003046"
    },
    {
      "id": 7191,
      "label": "proctitis",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        4590,
        6965,
        20399
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:3127",
          "EFO:0005628",
          "ICD9:569.49",
          "MEDGEN:46113",
          "MESH:D011349",
          "NCIT:C38011",
          "SCTID:3951002",
          "UMLS:C0033246"
        ],
        "synonyms": [
          "anus inflammation",
          "inflammation of anus",
          "rectitis"
        ],
        "categories": [
          {
            "ref": "MONDO:0004335",
            "name": "digestive system disorder"
          },
          {
            "ref": "MONDO:0005046",
            "name": "immune system disorder"
          }
        ],
        "definition": "An inflammatory process affecting the anus. It is usually caused by sexually transmitted infectious agents and/or inflammatory bowel disease."
      },
      "child_count": 6,
      "reference_id": "MONDO:0005538"
    },
    {
      "id": 21252,
      "label": "levator syndrome",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        4370,
        4590
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "MEDGEN:98071",
          "MESH:C535890",
          "NCIT:C113615",
          "SCTID:62647006",
          "UMLS:C0423738",
          "icd11.foundation:1042451642"
        ],
        "synonyms": [
          "levator syndrome",
          "painful spasm of anus",
          "anorectal spasm",
          "levator ani spasm syndrome",
          "levator ani syndrome",
          "paroxysmal proctalgia",
          "proctalgia fugax",
          "psychogenic anal spasm"
        ],
        "categories": [
          {
            "ref": "MONDO:0002254",
            "name": "syndromic disease"
          },
          {
            "ref": "MONDO:0004335",
            "name": "digestive system disorder"
          }
        ],
        "definition": "Levator syndrome is characterized by sporadic pain in the rectum caused by spasm of a muscle near the anus (the levator ani muscle). The muscle spasm causes pain that typically is not related to defecation. The pain usually lasts less than 20 minutes. Pain may be brief and intense or a vague ache high in the rectum. It may occur spontaneously or with sitting and can waken a person from sleep. The pain may feel as if it would be relieved by the passage of gas or a bowel movement. In severe cases, the pain can persist for many hours and can recur frequently. A person may have undergone various unsuccessful rectal operations to relieve these symptoms."
      },
      "child_count": 0,
      "reference_id": "MONDO:0023628"
    },
    {
      "id": 23751,
      "label": "anal polyp",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        4590,
        20549,
        21327
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "ICD10CM:K62.0",
          "MEDGEN:75637",
          "NCIT:C3957",
          "SCTID:88580009",
          "UMLS:C0267573",
          "icd11.foundation:2038426249"
        ],
        "synonyms": [
          "anal polyp",
          "polyp of anus",
          "polyp of the anus"
        ],
        "categories": [
          {
            "ref": "MONDO:0004335",
            "name": "digestive system disorder"
          }
        ],
        "definition": "A non-neoplastic or neoplastic polypoid lesion that arises from the anus. Representative examples include the fibroepithelial polyp and squamous papilloma."
      },
      "child_count": 3,
      "reference_id": "MONDO:0060766"
    }
  ],
  "roots": [
    {
      "id": 3792,
      "label": "rectal disorder"
    }
  ]
}