{ "id": 4597, "label": "synovium neoplasm", "model": { "label": "Mondo Disease Ontology (MONDO)", "source": 0 }, "type_id": 0, "reference_id": "MONDO:0002528", "properties": { "xrefs": [ "DOID:315", "MEDGEN:99197", "NCIT:C8964", "UMLS:C0476203" ], "synonyms": [ "neoplasm of synovial membrane of synovial joint", "neoplasm of synovium", "neoplasm of the synovium", "synovial membrane of synovial joint neoplasm", "synovial membrane of synovial joint neoplasm (disease)", "synovial membrane of synovial joint tumor", "synovial membrane of synovial joint tumour", "synovial neoplasm", "synovial neoplasm (morphologic abnormality)", "synovial neoplasm NOS (morphologic abnormality)", "synovial tumor", "synovial tumour", "tumor of synovial membrane of synovial joint", "tumor of synovium", "tumor of the synovium", "tumour of synovial membrane of synovial joint", "tumour of synovium", "tumour of the synovium" ], "categories": [ { "ref": "MONDO:0002081", "name": "musculoskeletal system disorder" } ], "definition": "A benign or malignant soft tissue neoplasm arising exclusively from the synovial membrane. Examples include the diffuse giant cell tumor of tendon sheath, localized giant cell tumor of tendon sheath, and malignant giant cell tumor of tendon sheath." }, "isLeaf": false, "isRoot": false, "child_count": 3, "parents": [ { "id": 7941, "label": "soft tissue neoplasm", "isLeaf": false, "isRoot": false, "parents": [ 23336 ], "type_id": 0, "properties": { "xrefs": [ "EFO:1000541", "MEDGEN:11495", "NCIT:C3377", "ONCOTREE:SOFT_TISSUE", "SCTID:387837005", "UMLS:C0037579" ], "synonyms": [ "neoplasm of soft tissue", "neoplasm of the soft tissue", "soft tissue neoplasm", "soft tissue tumor", "soft tissue tumors", "soft tissue tumour", "soft tissue tumours", "tumor of soft tissue", "tumor of the soft tissue", "tumour of soft tissue", "tumour of the soft tissue", "SOFT_TISSUE" ], "definition": "A benign, intermediate, or malignant neoplasm that arises from the soft tissue. The most common types are lipomatous (fatty), vascular, smooth muscle, fibrous, and fibrohistiocytic neoplasms." }, "child_count": 18, "reference_id": "MONDO:0006424" }, { "id": 8264, "label": "arthropathy", "isLeaf": false, "isRoot": false, "parents": [ 6893 ], "type_id": 0, "properties": { "xrefs": [ "DOID:381", "EFO:1000999", "ICD9:711", "ICD9:716.80", "ICD9:716.88", "ICD9:716.9", "ICD9:716.90", "ICD9:716.98", "ICD9:719.80", "ICD9:719.88", "ICD9:719.89", "ICD9:719.9", "ICD9:719.90", "ICD9:719.98", "MEDGEN:7190", "MESH:D007592", "MedDRA:10003285", "NCIT:C35760", "SCTID:399269003", "UMLS:C0022408" ], "synonyms": [ "Joint disorder", "arthropathy", "disease of skeletal joint", "disease or disorder of skeletal joint", "disorder of skeletal joint", "disorder, Joint", "skeletal joint disease", "skeletal joint disease or disorder", "Joint ankylosis of the ankle and foot", "Joint ankylosis of the forearm", "Joint ankylosis of the hand", "Joint ankylosis of the lower leg", "Joint ankylosis of the pelvic region and thigh", "Joint ankylosis of the shoulder region", "Joint ankylosis of the upper arm", "ankylosis of ankle and foot joint", "ankylosis of forearm joint", "ankylosis of hand joint", "ankylosis of joint of multiple sites", "ankylosis of joint of pelvic region and thigh", "ankylosis of joint of shoulder region", "ankylosis of lower leg joint", "ankylosis of multiple joints", "ankylosis of upper arm joint", "infectious arthropathy", "arthrosis", "disorder of joint", "joint disease", "joint disorder" ], "categories": [ { "ref": "MONDO:0002081", "name": "musculoskeletal system disorder" } ], "definition": "Any disorder of the joints." }, "child_count": 24, "reference_id": "MONDO:0006816" }, { "id": 23662, "label": "synovium disorder", "isLeaf": false, "isRoot": false, "parents": [ 4222 ], "type_id": 0, "properties": { "xrefs": [ "ICD9:727.89", "ICD9:727.9", "MEDGEN:538212", "SCTID:3519007", "UMLS:C0263945" ], "synonyms": [ "disease of layer of synovial tissue", "disease or disorder of layer of synovial tissue", "disorder of layer of synovial tissue", "disorder of synovium", "layer of synovial tissue disease", "layer of synovial tissue disease or disorder" ], "categories": [ { "ref": "MONDO:0002081", "name": "musculoskeletal system disorder" } ], "definition": "A disease or disorder that involves the layer of synovial tissue." }, "child_count": 4, "reference_id": "MONDO:0056799" } ], "children": [ { "id": 4493, "label": "synovium cancer", "isLeaf": false, "isRoot": false, "parents": [ 3041, 4597 ], "type_id": 0, "properties": { "xrefs": [ "DOID:2706", "GARD:0027607", "MEDGEN:277340", "NCIT:C6531", "UMLS:C1334624" ], "synonyms": [ "cancer of layer of synovial tissue", "cancer of synovial membrane of synovial joint", "layer of synovial tissue cancer", "malignant layer of synovial tissue neoplasm", "malignant neoplasm of layer of synovial tissue", "malignant neoplasm of synovial membrane of synovial joint", "malignant neoplasm of synovium", "malignant neoplasm of the synovium", "malignant synovial membrane of synovial joint neoplasm", "malignant synovial neoplasm", "malignant synovial tumor", "malignant synovial tumour", "malignant tumor of synovium", "malignant tumor of the synovium", "malignant tumour of synovium", "malignant tumour of the synovium", "synovial membrane of synovial joint cancer" ], "categories": [ { "ref": "MONDO:0002081", "name": "musculoskeletal system disorder" } ], "definition": "A cancer that involves the layer of synovial tissue." }, "child_count": 2, "reference_id": "MONDO:0002403" }, { "id": 4592, "label": "tenosynovial giant cell tumor", "isLeaf": false, "isRoot": false, "parents": [ 4297, 4597, 20678, 21600 ], "type_id": 0, "properties": { "xrefs": [ "DOID:314", "EFO:1000562", "ICD9:727.89", "ICDO:9252/0", "MEDGEN:232927", "NCIT:C3402", "SCTID:310605004", "UMLS:C1318543" ], "synonyms": [ "fibrous histiocytoma of tendon sheath", "giant cell neoplasm of Tenosynovium", "giant cell neoplasm of tendon sheath", "giant cell neoplasm of the Tenosynovium", "giant cell tumor of Tenosynovium", "giant cell tumor of tendon sheath", "giant cell tumor of the Tenosynovium", "giant cell tumour of the Tenosynovium", "tendon sheath giant cell neoplasm", "tendon sheath giant cell tumor", "tendon sheath giant cell tumour", "tenosynovial giant cell neoplasm", "tenosynovial giant cell tumor" ], "categories": [ { "ref": "MONDO:0002081", "name": "musculoskeletal system disorder" }, { "ref": "MONDO:0003900", "name": "connective tissue disorder" } ], "definition": "A tumor usually arising in the synovium of joints, bursa or tendon sheath. It is characterized by the presence of mononuclear cells, multinucleated osteoclast-like giant cells, hemosiderin-laden macrophages, foam cells, and an inflammatory infiltrate. According to the growth pattern, it is classified as localized or diffuse." }, "child_count": 12, "reference_id": "MONDO:0002522" }, { "id": 21582, "label": "benign synovial neoplasm", "isLeaf": false, "isRoot": false, "parents": [ 4597, 23337 ], "type_id": 0, "properties": { "xrefs": [ "ICDO:9040/0", "MEDGEN:113161", "NCIT:C3829", "UMLS:C0221289" ], "synonyms": [ "benign neoplasm of synovium", "benign neoplasm of the synovium", "benign synovial neoplasm", "benign synovial tumor", "benign synovial tumour", "benign synovioma", "benign synovium neoplasm", "benign tumor of synovium", "benign tumor of the synovium", "benign tumour of synovium", "benign tumour of the synovium", "synovioma, benign", "synovium neoplasm, benign" ], "categories": [ { "ref": "MONDO:0002081", "name": "musculoskeletal system disorder" }, { "ref": "MONDO:0003900", "name": "connective tissue disorder" } ], "definition": "A benign neoplasm arising from the synovial membrane. Examples include the diffuse giant cell tumor of tendon sheath and localized giant cell tumor of tendon sheath." }, "child_count": 8, "reference_id": "MONDO:0024715" } ], "roots": [ { "id": 7941, "label": "soft tissue neoplasm" }, { "id": 8264, "label": "arthropathy" }, { "id": 23662, "label": "synovium disorder" } ] }