{
  "id": 4608,
  "label": "spinal cord glioma",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0002542",
  "properties": {
    "xrefs": [
      "DOID:3185",
      "GARD:0023158",
      "MEDGEN:423646",
      "NCIT:C4534",
      "SCTID:254946004",
      "UMLS:C2937245"
    ],
    "synonyms": [
      "glial neoplasm spinal cord",
      "glial tumor of spinal cord",
      "glial tumour of spinal cord",
      "malignant glioma of spinal cord",
      "spinal cord glial neoplasm",
      "spinal cord glial tumor",
      "spinal cord glial tumour",
      "spinal cord glioma",
      "spinal cord malignant glioma"
    ],
    "categories": [
      {
        "ref": "MONDO:0005071",
        "name": "nervous system disorder"
      }
    ],
    "definition": "A neoplasm that arises from glial cells in the spinal cord. Representative examples include astrocytoma, oligodendroglioma, and ependymoma."
  },
  "isLeaf": false,
  "isRoot": false,
  "child_count": 4,
  "parents": [
    {
      "id": 5449,
      "label": "spinal cord cancer",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        4753,
        20444
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:5612",
          "GARD:0027641",
          "ICD10CM:C72.0",
          "ICD9:192.2",
          "MEDGEN:56317",
          "NCIT:C3572",
          "SCTID:363475005",
          "UMLS:C0153646",
          "icd11.foundation:492029077"
        ],
        "synonyms": [
          "intraspinal tumor",
          "intraspinal tumour",
          "spinal cord neoplasm",
          "tumor of the spinal cord",
          "tumour of the spinal cord",
          "cancer of spinal cord",
          "malignant neoplasm of spinal cord",
          "malignant neoplasm of the spinal cord",
          "malignant spinal cord neoplasm",
          "malignant spinal cord tumor",
          "malignant spinal cord tumour",
          "malignant tumor of spinal cord",
          "malignant tumor of the spinal cord",
          "malignant tumour of spinal cord",
          "malignant tumour of the spinal cord",
          "spinal cord cancer",
          "spine cancer"
        ],
        "categories": [
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "A primary or metastatic malignant neoplasm affecting the spinal cord. Representative examples include lymphoma, melanoma, and sarcoma."
      },
      "child_count": 16,
      "reference_id": "MONDO:0003544"
    },
    {
      "id": 24071,
      "label": "malignant glioma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        4753,
        20078,
        20287
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:3070",
          "GARD:0026148",
          "ICDO:9380/3",
          "MEDGEN:107826",
          "MedDRA:10018338",
          "NCIT:C4822",
          "UMLS:C0555198"
        ],
        "synonyms": [
          "glioma",
          "neuroglial tumor",
          "neuroglial tumour",
          "glial cell tumour",
          "glioma, malignant",
          "high grade glioma",
          "high-grade glioma",
          "malignant glial neoplasm",
          "malignant glial tumor",
          "malignant glial tumour",
          "malignant glioma",
          "malignant neuroglial neoplasm",
          "malignant neuroglial tumor",
          "malignant neuroglial tumour"
        ],
        "categories": [
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "A grade III or grade IV glioma arising from the central nervous system. This category includes glioblastoma, anaplastic astrocytoma, anaplastic ependymoma, anaplastic oligodendroglioma, and anaplastic oligoastrocytoma."
      },
      "child_count": 36,
      "reference_id": "MONDO:0100342"
    }
  ],
  "children": [
    {
      "id": 4607,
      "label": "spinal cord oligodendroglioma",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        4608,
        17158
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:3184",
          "GARD:0023157",
          "MEDGEN:138055",
          "NCIT:C4535",
          "SCTID:254950006",
          "UMLS:C0346295"
        ],
        "synonyms": [
          "oligodendroglioma of spinal cord",
          "spinal cord oligodendroglioma",
          "well differentiated spinal cord oligodendroglial tumor",
          "well differentiated spinal cord oligodendroglial tumour",
          "well differentiated spinal cord oligodendroglioma"
        ],
        "categories": [
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "A oligodendroglioma that involves the spinal cord."
      },
      "child_count": 0,
      "reference_id": "MONDO:0002541"
    },
    {
      "id": 5138,
      "label": "spinal cord astrocytoma",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        4608,
        19525
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:4863",
          "EFO:1000544",
          "GARD:0023397",
          "MEDGEN:91152",
          "NCIT:C4641",
          "SCTID:254948003",
          "UMLS:C0349540"
        ],
        "synonyms": [
          "astrocytoma (excluding glioblastoma) of spinal cord",
          "astrocytoma of spinal cord",
          "astrocytoma of the spinal cord",
          "spinal astrocytoma",
          "spinal cord astrocytoma",
          "spinal cord astrocytoma (excluding glioblastoma)"
        ],
        "categories": [
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "A low or high grade astrocytoma that arises in the spinal cord."
      },
      "child_count": 0,
      "reference_id": "MONDO:0003174"
    },
    {
      "id": 6176,
      "label": "adult spinal cord glioblastoma",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        4608,
        20099
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:7806",
          "GARD:0023957",
          "MEDGEN:107849",
          "NCIT:C27183",
          "SCTID:276829003",
          "UMLS:C0559185"
        ],
        "synonyms": [
          "adult spinal cord glioblastoma",
          "adult spinal cord glioblastoma multiforme"
        ],
        "categories": [
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "A rare spinal tumor which is highly malignant and tends to be locally invasive of surrounding neural tissue. The tumor also tends to spread throughout the neuroaxis and is often rapidly progressive. Histologically the tumors are highly cellular with nuclear and cellular pleomorphism, endothelial proliferation, mitotic figures, and, often, necrosis. This tumor has a relatively poor prognosis. Clinical features may include pain followed by rapidly progressive neurologic deficits such as extremity weakness, sensory changes, spasticity, and incontinence. (From Innocenzi et al., Clin Neurol Neurosurg 1997 Feb;99(1):1-5)"
      },
      "child_count": 0,
      "reference_id": "MONDO:0004363"
    },
    {
      "id": 20661,
      "label": "ependymal tumor of spinal cord",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        4608,
        5210
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0025336",
          "MEDGEN:1389203",
          "NCIT:C131526",
          "UMLS:C4318747"
        ],
        "synonyms": [
          "ependymal tumor of spinal cord",
          "spinal cord ependymal tumor",
          "spinal cord ependymal tumour"
        ],
        "categories": [
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "An ependymal tumor that arises from the spinal cord."
      },
      "child_count": 2,
      "reference_id": "MONDO:0021546"
    }
  ],
  "roots": [
    {
      "id": 5449,
      "label": "spinal cord cancer"
    },
    {
      "id": 24071,
      "label": "malignant glioma"
    }
  ]
}