{
  "id": 4623,
  "label": "melanotic neurilemmoma",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0002558",
  "properties": {
    "xrefs": [
      "DOID:3205",
      "GARD:0023167",
      "ICD9:215.8",
      "MEDGEN:266292",
      "NCIT:C6970",
      "ONCOTREE:MSCHW",
      "SCTID:404024000",
      "UMLS:C1306247"
    ],
    "synonyms": [
      "melanocytic neurilemmoma",
      "melanocytic schwannoma",
      "melanotic neurinoma",
      "melanotic schwannoma",
      "melanotic schwannoma (morphologic abnormality)",
      "pigmented neurilemmoma",
      "pigmented schwannoma",
      "MSCHW"
    ],
    "categories": [
      {
        "ref": "MONDO:0005071",
        "name": "nervous system disorder"
      }
    ],
    "definition": "A rare circumscribed, non-encapsulated and grossly pigmented nerve sheath tumor. It is composed of cells with the immunophenotypic and electron microscopic features of Schwann cells which contain melanosomes and are positive for melanoma markers. It usually involves spinal nerve roots but may occur in other locations. It may be associated with PRKAR1A gene mutation and Carney complex. Malignant behavior has been reported in a significant number of patients."
  },
  "isLeaf": false,
  "isRoot": false,
  "child_count": 2,
  "parents": [
    {
      "id": 4612,
      "label": "schwannoma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        4613,
        17200,
        20693
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:3192",
          "DOID:955",
          "EFO:0000693",
          "GARD:0004767",
          "ICD9:215.9",
          "ICDO:9560/0",
          "MEDGEN:45053",
          "MedDRA:10029234",
          "MedDRA:10029235",
          "NANDO:2200103",
          "NCIT:C3269",
          "ONCOTREE:SCHW",
          "Orphanet:252164",
          "SCTID:404022001",
          "UMLS:C0027809",
          "icd11.foundation:378766741"
        ],
        "synonyms": [
          "benign neurilemmoma",
          "benign schwannoma",
          "neurilemmoma",
          "neurinoma",
          "peripheral fibroblastoma",
          "schwannoma",
          "schwannoma (WHO grade I)",
          "schwannoma, benign",
          "SCHW",
          "neurolemmoma"
        ],
        "categories": [
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "A benign, usually encapsulated slow growing tumor composed of Schwann cells. It affects peripheral and cranial nerves. It recurs infrequently and only rare cases associated with malignant transformation have been reported."
      },
      "child_count": 30,
      "reference_id": "MONDO:0002546"
    }
  ],
  "children": [
    {
      "id": 5756,
      "label": "mediastinal melanocytic neurilemmoma",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        4623
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:6484",
          "GARD:0023718",
          "MEDGEN:277352",
          "NCIT:C6635",
          "UMLS:C1334668"
        ],
        "synonyms": [
          "mediastinal melanocytic schwannoma",
          "mediastinal melanotic schwannoma",
          "melanocytic neurilemmoma of mediastinum",
          "melanocytic neurilemmoma of the mediastinum",
          "melanocytic schwannoma of mediastinum",
          "melanocytic schwannoma of the mediastinum"
        ],
        "categories": [
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "A melanotic schwannoma that affects the mediastinum."
      },
      "child_count": 0,
      "reference_id": "MONDO:0003894"
    },
    {
      "id": 22804,
      "label": "isolated melanotic schwannoma",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        4336,
        4623,
        20329,
        24071
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0022368",
          "Orphanet:590539"
        ],
        "categories": [
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ]
      },
      "child_count": 0,
      "reference_id": "MONDO:0035136"
    }
  ],
  "roots": [
    {
      "id": 4612,
      "label": "schwannoma"
    }
  ]
}