{
  "id": 4630,
  "label": "tracheal disorder",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0002567",
  "properties": {
    "xrefs": [
      "DOID:3225",
      "MEDGEN:892789",
      "MESH:D014133",
      "NCIT:C35079",
      "SCTID:47125007",
      "UMLS:C4025678"
    ],
    "synonyms": [
      "disease of trachea",
      "disease or disorder of trachea",
      "disorder of trachea",
      "trachea disease",
      "trachea disease or disorder",
      "tracheal disorder"
    ],
    "categories": [
      {
        "ref": "MONDO:0005087",
        "name": "respiratory system disorder"
      }
    ],
    "definition": "A non-neoplastic or neoplastic disorder that affects the trachea. Representative examples of non-neoplastic disorders include congenital malformations and infection. Representative examples of neoplastic disorders include carcinoma and lymphoma."
  },
  "isLeaf": false,
  "isRoot": false,
  "child_count": 8,
  "parents": [
    {
      "id": 2809,
      "label": "lower respiratory tract disorder",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6815
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0050161",
          "EFO:0009433",
          "ICD9:478.1",
          "ICD9:478.19",
          "MEDGEN:712703",
          "SCTID:128272009",
          "UMLS:C1290325",
          "icd11.foundation:1582386590"
        ],
        "synonyms": [
          "disease of lower respiratory tract",
          "disease or disorder of lower respiratory tract",
          "disorder of lower respiratory tract",
          "lower respiratory tract disease",
          "lower respiratory tract disease or disorder"
        ],
        "categories": [
          {
            "ref": "MONDO:0005087",
            "name": "respiratory system disorder"
          }
        ],
        "definition": "A disease involving the lower respiratory tract."
      },
      "child_count": 5,
      "reference_id": "MONDO:0000270"
    },
    {
      "id": 6623,
      "label": "upper respiratory tract disorder",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6815
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:974",
          "ICD9:478.1",
          "ICD9:478.19",
          "ICD9:478.9",
          "MEDGEN:538406",
          "SCTID:201060008",
          "UMLS:C0264221"
        ],
        "synonyms": [
          "disease of upper respiratory tract",
          "disease or disorder of upper respiratory tract",
          "disorder of upper respiratory tract",
          "upper respiratory tract disease",
          "upper respiratory tract disease or disorder"
        ],
        "categories": [
          {
            "ref": "MONDO:0005087",
            "name": "respiratory system disorder"
          }
        ],
        "definition": "A disease involving the upper respiratory tract."
      },
      "child_count": 10,
      "reference_id": "MONDO:0004867"
    }
  ],
  "children": [
    {
      "id": 4083,
      "label": "tracheal calcification",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        4630
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:14224",
          "HP:0002787",
          "ICD9:519.19",
          "MEDGEN:75539",
          "SCTID:81089005",
          "UMLS:C0264324"
        ],
        "categories": [
          {
            "ref": "MONDO:0005087",
            "name": "respiratory system disorder"
          }
        ],
        "definition": "Abnormal deposits of calcium in the tracheal tissue."
      },
      "child_count": 0,
      "reference_id": "MONDO:0001911"
    },
    {
      "id": 4631,
      "label": "tracheal stenosis",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        4630
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:3227",
          "ICD9:519.19",
          "MEDGEN:21227",
          "MESH:D014135",
          "NANDO:2200194",
          "NCIT:C78646",
          "SCTID:11296007",
          "UMLS:C0040583"
        ],
        "categories": [
          {
            "ref": "MONDO:0005087",
            "name": "respiratory system disorder"
          }
        ],
        "definition": "Narrowing of the lumen of the trachea."
      },
      "child_count": 0,
      "reference_id": "MONDO:0002568"
    },
    {
      "id": 6740,
      "label": "chronic obstructive pulmonary disease",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        4382,
        4630
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:3083",
          "EFO:0000341",
          "ICD9:490-496",
          "ICD9:496",
          "MEDGEN:9818",
          "MESH:D029424",
          "NCIT:C3199",
          "OMIM:606963",
          "SCTID:13645005",
          "UMLS:C0024117",
          "icd11.foundation:133207228"
        ],
        "synonyms": [
          "COLD",
          "COPD",
          "COPD, chronic obstructive pulmonary disease",
          "chronic obstructive airways disease",
          "chronic obstructive lung disease",
          "chronic obstructive pulmonary disease (COPD)",
          "chronic obstructive pulmonary disease, (COPD)",
          "cold",
          "cold (chronic obstructive lung disease)",
          "disease (COPD), chronic obstructive",
          "obstructive lung disease, chronic",
          "obstructive pulmonary disease (COPD), chronic",
          "pulmonary disease (COPD), chronic obstructive"
        ],
        "categories": [
          {
            "ref": "MONDO:0005087",
            "name": "respiratory system disorder"
          }
        ],
        "definition": "A chronic and progressive lung disorder characterized by the loss of elasticity of the bronchial tree and the air sacs, destruction of the air sacs wall, thickening of the bronchial wall, and mucous accumulation in the bronchial tree. The pathologic changes result in the disruption of the air flow in the bronchial airways. Signs and symptoms include shortness of breath, wheezing, productive cough, and chest tightness. The two main types of chronic obstructive pulmonary disease are chronic obstructive bronchitis and emphysema."
      },
      "child_count": 10,
      "reference_id": "MONDO:0005002"
    },
    {
      "id": 7582,
      "label": "tracheitis",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        4630,
        6839,
        20016,
        20781,
        21378
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:9392",
          "EFO:0007518",
          "ICD10CM:J04.1",
          "ICD9:464.1",
          "MEDGEN:11870",
          "MESH:D014136",
          "NCIT:C78643",
          "SCTID:62994001",
          "UMLS:C0040584"
        ],
        "synonyms": [
          "acute tracheitis",
          "inflammation of tracheal mucosa",
          "tracheal Inflammation",
          "tracheal mucosa inflammation"
        ],
        "categories": [
          {
            "ref": "MONDO:0005087",
            "name": "respiratory system disorder"
          }
        ],
        "definition": "A tracheal disease which involves bacterial infection of the trachea often caused by Staphylococcus aureus and streptococci that follows a recent viral upper respiratory infection. The symptoms include barking croup cough, loud squeaking noise while breathing, scratchy feeling in the throat, high fever, and production of large amounts of pus-filled secretions."
      },
      "child_count": 5,
      "reference_id": "MONDO:0005990"
    },
    {
      "id": 16693,
      "label": "laryngotracheoesophageal cleft",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        4630,
        5629
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0003188",
          "MESH:C537875",
          "NCIT:C98622",
          "Orphanet:2004",
          "SCTID:232461002",
          "icd11.foundation:271795917"
        ],
        "synonyms": [
          "LC",
          "LTEC",
          "Larnygeotracheoesophageal cleft",
          "congenital cleft larynx",
          "laryngeal cleft",
          "laryngo-tracheo-esophageal cleft",
          "laryngo-tracheo-esophageal diastema",
          "tracheal cleft"
        ],
        "categories": [
          {
            "ref": "MONDO:0004335",
            "name": "digestive system disorder"
          },
          {
            "ref": "MONDO:0005087",
            "name": "respiratory system disorder"
          }
        ],
        "definition": "A laryngo-tracheo-esophageal cleft (LC) is a congenital malformation characterized by an abnormal, posterior, sagittal communication between the larynx and the pharynx, possibly extending downward between the trachea and the esophagus."
      },
      "child_count": 12,
      "reference_id": "MONDO:0016060"
    },
    {
      "id": 18683,
      "label": "isolated tracheo-esophageal fistula",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        4630,
        5629
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0021895",
          "NCIT:C35080",
          "Orphanet:454750"
        ],
        "synonyms": [
          "H-type tracheoesophageal fistula",
          "tracheo-esophageal fistula",
          "tracheoesophageal fistula",
          "isolated tracheoesophageal fistula"
        ],
        "categories": [
          {
            "ref": "MONDO:0004335",
            "name": "digestive system disorder"
          },
          {
            "ref": "MONDO:0005087",
            "name": "respiratory system disorder"
          }
        ],
        "definition": "A rare, congenital, esophageal disorder characterized by the presence of an abnormal connection between the esophagus and the trachea (typically occurring in the lower cervical or upper thoracic area and taking an oblique path upward to trachea), without concomitant esophageal atresia. Depending on the size of the lumen, presentation varies from neonatal episodes of choking and cyanosis on feeding to subtle symptoms of wheezing and recurrent respiratory infections in childhood or early adulthood."
      },
      "child_count": 0,
      "reference_id": "MONDO:0018694"
    },
    {
      "id": 19545,
      "label": "congenital tracheomalacia",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        4630,
        21538
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0060313",
          "GARD:0010515",
          "HP:0002779",
          "ICD9:748.3",
          "MEDGEN:140261",
          "MESH:D055090",
          "MedDRA:10010654",
          "NANDO:2200195",
          "NCIT:C98634",
          "NORD:2028",
          "Orphanet:95430",
          "SCTID:95467005",
          "UMLS:C0392109",
          "icd11.foundation:1616705280",
          "icd11.foundation:303133490"
        ],
        "synonyms": [
          "Congenital Tracheomalacia",
          "congenital major airway collapse",
          "congenital tracheomalacia",
          "tracheomalacia, congenital",
          "tracheomalacia",
          "type 1 tracheomalacia"
        ],
        "categories": [
          {
            "ref": "MONDO:0005087",
            "name": "respiratory system disorder"
          },
          {
            "ref": "MONDO:0024623",
            "name": "otorhinolaryngologic disease"
          }
        ],
        "definition": "Congenital tracheomalacia is a rare condition where the trachea is soft and flexible causing the tracheal wall to collapse when exhaling, coughing or crying, that usually presents in infancy, and that is characterized by stridor and noisy breathing or upper respiratory infections. Tracheomalacia improves by the age of 18-24 months."
      },
      "child_count": 0,
      "reference_id": "MONDO:0019804"
    },
    {
      "id": 20428,
      "label": "trachea neoplasm",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        4630,
        20056
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "EFO:1001437",
          "GTR:AN0481062",
          "GTR:AN0505660",
          "HP:0100551",
          "MEDGEN:21602",
          "MESH:D014134",
          "NCIT:C3419",
          "UMLS:C0040582"
        ],
        "synonyms": [
          "neoplasm of the trachea",
          "neoplasm of trachea",
          "trachea neoplasm (disease)",
          "trachea tumor",
          "trachea tumour",
          "tracheal neoplasm",
          "tracheal tumor",
          "tracheal tumour",
          "tumor of the trachea",
          "tumor of trachea",
          "tumour of the trachea",
          "tumour of trachea"
        ],
        "categories": [
          {
            "ref": "MONDO:0005087",
            "name": "respiratory system disorder"
          }
        ],
        "definition": "A neoplasm (disease) that involves the trachea."
      },
      "child_count": 4,
      "reference_id": "MONDO:0021210"
    }
  ],
  "roots": [
    {
      "id": 2809,
      "label": "lower respiratory tract disorder"
    },
    {
      "id": 6623,
      "label": "upper respiratory tract disorder"
    }
  ]
}