{
  "id": 4641,
  "label": "orbit rhabdomyosarcoma",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0002580",
  "properties": {
    "xrefs": [
      "DOID:3259",
      "GARD:0023174",
      "MEDGEN:83419",
      "MESH:C537605",
      "NCIT:C4543",
      "SCTID:254994000",
      "UMLS:C0346347"
    ],
    "synonyms": [
      "orbital region rhabdomyosarcoma",
      "orbital region rhabdomyosarcoma (disease)",
      "rhabdomyosarcoma (disease) of orbital region",
      "rhabdomyosarcoma of orbit",
      "rhabdomyosarcoma of the orbit"
    ],
    "categories": [
      {
        "ref": "MONDO:0002022",
        "name": "disorder of orbital region"
      },
      {
        "ref": "MONDO:0002081",
        "name": "musculoskeletal system disorder"
      },
      {
        "ref": "MONDO:0003900",
        "name": "connective tissue disorder"
      }
    ],
    "definition": "A malignant mesenchymal neoplasm with skeletal muscle differentiation that arises from the orbit."
  },
  "isLeaf": false,
  "isRoot": false,
  "child_count": 2,
  "parents": [
    {
      "id": 6689,
      "label": "orbit sarcoma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        4902,
        6816
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:9987",
          "GARD:0024134",
          "MEDGEN:277449",
          "NCIT:C6095",
          "SCTID:699354006",
          "UMLS:C1335131"
        ],
        "synonyms": [
          "orbit of skull sarcoma",
          "orbital sarcoma",
          "sarcoma of orbit",
          "sarcoma of orbit of skull",
          "sarcoma of the orbit"
        ],
        "categories": [
          {
            "ref": "MONDO:0002022",
            "name": "disorder of orbital region"
          },
          {
            "ref": "MONDO:0002081",
            "name": "musculoskeletal system disorder"
          },
          {
            "ref": "MONDO:0003900",
            "name": "connective tissue disorder"
          }
        ],
        "definition": "A malignant soft tissue neoplasm that arises from the structures of the orbit. The majority of the cases are rhabdomyosarcomas."
      },
      "child_count": 2,
      "reference_id": "MONDO:0004943"
    },
    {
      "id": 6928,
      "label": "rhabdomyosarcoma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        18239
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:3247",
          "EFO:0002918",
          "GARD:0011951",
          "HP:0002859",
          "ICD9:171.9",
          "ICDO:8900/3",
          "MEDGEN:20561",
          "MESH:D012208",
          "MedDRA:10039022",
          "NANDO:2200056",
          "NCIT:C3359",
          "ONCOTREE:RMS",
          "Orphanet:780",
          "SCTID:302847003",
          "UMLS:C0035412"
        ],
        "synonyms": [
          "rhabdomyosarcoma",
          "rhabdomyosarcoma (disease)",
          "rhabdomyosarcoma, malignant"
        ],
        "definition": "A rare aggressive malignant mesenchymal neoplasm arising from skeletal muscle. It usually occurs in children and young adults. Only a small percentage of tumors arise in the skeletal muscle of the extremities. The majority arise in other anatomical sites."
      },
      "child_count": 20,
      "reference_id": "MONDO:0005212"
    }
  ],
  "children": [
    {
      "id": 4640,
      "label": "orbit embryonal rhabdomyosarcoma",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        4641,
        11190
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:3258",
          "GARD:0023173",
          "MEDGEN:233267",
          "NCIT:C6246",
          "UMLS:C1335127"
        ],
        "synonyms": [
          "embryonal rhabdomyosarcoma of orbit",
          "embryonal rhabdomyosarcoma of the orbit"
        ],
        "categories": [
          {
            "ref": "MONDO:0002022",
            "name": "disorder of orbital region"
          },
          {
            "ref": "MONDO:0002081",
            "name": "musculoskeletal system disorder"
          },
          {
            "ref": "MONDO:0003900",
            "name": "connective tissue disorder"
          }
        ],
        "definition": "A malignant mesenchymal neoplasm that arises from the orbit. It is characterized by the presence of skeletal muscle tissue exhibiting embryonic features."
      },
      "child_count": 0,
      "reference_id": "MONDO:0002579"
    },
    {
      "id": 4982,
      "label": "orbit alveolar rhabdomyosarcoma",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        4641
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:4384",
          "GARD:0023311",
          "MEDGEN:235408",
          "NCIT:C6247",
          "UMLS:C1335126"
        ],
        "synonyms": [
          "alveolar rhabdomyosarcoma of orbit",
          "alveolar rhabdomyosarcoma of the orbit"
        ],
        "categories": [
          {
            "ref": "MONDO:0002022",
            "name": "disorder of orbital region"
          },
          {
            "ref": "MONDO:0002081",
            "name": "musculoskeletal system disorder"
          },
          {
            "ref": "MONDO:0003900",
            "name": "connective tissue disorder"
          }
        ],
        "definition": "A malignant mesenchymal neoplasm that arises in the orbit. It is characterized by the presence of round cells with myoblastic differentiation and a fibrovascular stroma."
      },
      "child_count": 0,
      "reference_id": "MONDO:0002978"
    }
  ],
  "roots": [
    {
      "id": 6689,
      "label": "orbit sarcoma"
    },
    {
      "id": 6928,
      "label": "rhabdomyosarcoma"
    }
  ]
}