{
  "id": 4642,
  "label": "spindle cell rhabdomyosarcoma",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0002581",
  "properties": {
    "xrefs": [
      "DOID:3260",
      "GARD:0023175",
      "ICD9:171.9",
      "ICDO:8912/3",
      "MEDGEN:224766",
      "NCIT:C6519",
      "ONCOTREE:SCRMS",
      "SCTID:404055006",
      "UMLS:C1266134"
    ],
    "synonyms": [
      "spindle cell rhabdomyosarcoma (morphologic abnormality)",
      "SCRMS"
    ],
    "definition": "An uncommon variant of rhabdomyosarcoma characterized by the presence of whorls of spindle cells forming a storiform pattern. In children it usually arises in the paratesticular region. In adults it usually arises from the deep soft tissues in the head and neck."
  },
  "isLeaf": false,
  "isRoot": false,
  "child_count": 3,
  "parents": [
    {
      "id": 4933,
      "label": "spindle cell sarcoma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6816,
        20076
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:4235",
          "ICDO:8801/3",
          "MEDGEN:64477",
          "NCIT:C27005",
          "UMLS:C0205945"
        ],
        "synonyms": [
          "spindle cell sarcoma"
        ],
        "definition": "A malignant mesenchymal neoplasm composed of spindle-shaped cells. This is a morphologic term which can be applied to a wide range of sarcomas."
      },
      "child_count": 8,
      "reference_id": "MONDO:0002927"
    },
    {
      "id": 6928,
      "label": "rhabdomyosarcoma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        18239
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:3247",
          "EFO:0002918",
          "GARD:0011951",
          "HP:0002859",
          "ICD9:171.9",
          "ICDO:8900/3",
          "MEDGEN:20561",
          "MESH:D012208",
          "MedDRA:10039022",
          "NANDO:2200056",
          "NCIT:C3359",
          "ONCOTREE:RMS",
          "Orphanet:780",
          "SCTID:302847003",
          "UMLS:C0035412"
        ],
        "synonyms": [
          "rhabdomyosarcoma",
          "rhabdomyosarcoma (disease)",
          "rhabdomyosarcoma, malignant"
        ],
        "definition": "A rare aggressive malignant mesenchymal neoplasm arising from skeletal muscle. It usually occurs in children and young adults. Only a small percentage of tumors arise in the skeletal muscle of the extremities. The majority arise in other anatomical sites."
      },
      "child_count": 20,
      "reference_id": "MONDO:0005212"
    }
  ],
  "children": [
    {
      "id": 23807,
      "label": "intraosseous spindle cell rhabdomyosarcoma with TFCP2/NCOA2 rearrangements",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        4642
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0026027",
          "MEDGEN:1791329",
          "NCIT:C178236",
          "UMLS:C5554888"
        ],
        "synonyms": [
          "intraosseous rhabdomyosarcoma with FUS-TFCP2 fusion",
          "intraosseous rhabdomyosarcoma defined by FUS-TFCP2 fusion"
        ],
        "definition": "Intraosseous spindle cell rhabdomyosarcoma characterized by the fusion of the EWSR1 or FUS gene with the TFCP2 gene, or the MEIS1 gene with the NCOA2 gene."
      },
      "child_count": 0,
      "reference_id": "MONDO:0100055"
    },
    {
      "id": 23812,
      "label": "congenital/infantile spindle cell rhabdomyosarcoma with VGLL2/NCOA2/CITED2 rearrangements",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        4642
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0026030",
          "MEDGEN:1791325",
          "NCIT:C178232",
          "UMLS:C5554884"
        ],
        "definition": "Congenital/infantile spindle cell rhabdomyosarcoma characterized by the presence of gene fusions involving the VGLL2, SRF, TEAD1, NCOA2, and CITED2 genes."
      },
      "child_count": 0,
      "reference_id": "MONDO:0100060"
    },
    {
      "id": 23819,
      "label": "childhood spindle cell rhabdomyosarcoma",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        4642
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0026034",
          "MEDGEN:882003",
          "NCIT:C123397",
          "UMLS:C4055242"
        ],
        "definition": "A spindle cell rhabdomyosarcoma occurring in children."
      },
      "child_count": 0,
      "reference_id": "MONDO:0100067"
    }
  ],
  "roots": [
    {
      "id": 4933,
      "label": "spindle cell sarcoma"
    },
    {
      "id": 6928,
      "label": "rhabdomyosarcoma"
    }
  ]
}