{
  "id": 4648,
  "label": "thymoma type A",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0002588",
  "properties": {
    "xrefs": [
      "DOID:3279",
      "GARD:0020892",
      "ICDO:8581/1",
      "MEDGEN:266099",
      "NCIT:C6454",
      "Orphanet:263310",
      "UMLS:C1266091"
    ],
    "synonyms": [
      "medullary thymoma",
      "primary thymic epithelial neoplasm type A",
      "primary thymic epithelial tumor type A",
      "primary thymic epithelial tumour type A",
      "spindle cell thymoma",
      "thymoma type A"
    ],
    "categories": [
      {
        "ref": "MONDO:0005046",
        "name": "immune system disorder"
      },
      {
        "ref": "MONDO:0005151",
        "name": "endocrine system disorder"
      },
      {
        "ref": "MONDO:0005570",
        "name": "hematologic disorder"
      }
    ],
    "definition": "A thymic epithelial neoplasm characterized by the presence of spindle and/or oval neoplastic epithelial cells. Lymphocytic infiltration is minimal or absent. It may be associated with myasthenia gravis or pure red cell aplasia. The majority of cases occur in the anterior mediastinum as Masaoka stage I tumors. Approximately 20% of the cases occur as stage II or stage III tumors. Type A thymoma generally behaves as a benign tumor and the overall survival is reported to be 100% at 5 and 10 years."
  },
  "isLeaf": false,
  "isRoot": false,
  "child_count": 1,
  "parents": [
    {
      "id": 7959,
      "label": "thymoma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        18240
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:3275",
          "EFO:1000581",
          "GARD:0016922",
          "HP:0100522",
          "ICD9:239.89",
          "ICDO:8580/1",
          "MEDGEN:52743",
          "MESH:D013945",
          "MedDRA:10043670",
          "NCIT:C3411",
          "ONCOTREE:THYM",
          "Orphanet:99867",
          "SCTID:444231005",
          "UMLS:C0040100",
          "icd11.foundation:33869057"
        ],
        "synonyms": [
          "primary thymic epithelial neoplasm",
          "primary thymic epithelial tumor",
          "primary thymic epithelial tumour",
          "thymoma",
          "thymoma (disease)",
          "THYM"
        ],
        "categories": [
          {
            "ref": "MONDO:0005046",
            "name": "immune system disorder"
          },
          {
            "ref": "MONDO:0005151",
            "name": "endocrine system disorder"
          },
          {
            "ref": "MONDO:0005570",
            "name": "hematologic disorder"
          }
        ],
        "definition": "A neoplasm arising from the epithelial cells of the thymus. Although thymomas are usually encapsulated tumors, they may invade the capsule and infiltrate the surrounding tissues or even metastasize to distant anatomic sites. The following morphologic subtypes are currently recognized: type A, type B, type AB, metaplastic, micronodular, microscopic, and sclerosing thymoma. Thymomas type B are further subdivided into types B1, B2, and B3. Thymoma type B3 usually has the most aggressive clinical course."
      },
      "child_count": 8,
      "reference_id": "MONDO:0006456"
    }
  ],
  "children": [
    {
      "id": 6209,
      "label": "malignant type A thymoma",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        4648
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:7927",
          "GARD:0023979",
          "ICDO:8581/3",
          "MEDGEN:79027",
          "NCIT:C7999",
          "UMLS:C0279707"
        ],
        "synonyms": [
          "malignant type A thymoma"
        ],
        "categories": [
          {
            "ref": "MONDO:0005046",
            "name": "immune system disorder"
          },
          {
            "ref": "MONDO:0005151",
            "name": "endocrine system disorder"
          },
          {
            "ref": "MONDO:0005570",
            "name": "hematologic disorder"
          }
        ],
        "definition": "A type A thymoma which is characterized by an aggressive clinical course (capsular invasion, infiltration of the surrounding tissues) and can metastasize."
      },
      "child_count": 0,
      "reference_id": "MONDO:0004400"
    }
  ],
  "roots": [
    {
      "id": 7959,
      "label": "thymoma"
    }
  ]
}