{
  "id": 4650,
  "label": "invasive malignant thymoma",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0002592",
  "properties": {
    "xrefs": [
      "DOID:3283",
      "GARD:0023180",
      "MEDGEN:78892",
      "NCIT:C7904",
      "UMLS:C0278846"
    ],
    "synonyms": [
      "invasive malignant thymoma",
      "malignant thymoma, invasive",
      "thymoma malignant invasive"
    ],
    "categories": [
      {
        "ref": "MONDO:0005046",
        "name": "immune system disorder"
      },
      {
        "ref": "MONDO:0005151",
        "name": "endocrine system disorder"
      },
      {
        "ref": "MONDO:0005570",
        "name": "hematologic disorder"
      }
    ],
    "definition": "A malignant thymoma that extends beyond the capsule and infiltrates the surrounding tissues."
  },
  "isLeaf": true,
  "isRoot": false,
  "child_count": 0,
  "parents": [
    {
      "id": 7956,
      "label": "thymic carcinoma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        4646,
        6734,
        18240
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:3284",
          "DOID:4554",
          "EFO:1000576",
          "GARD:0019695",
          "ICDO:8586/3",
          "MEDGEN:60049",
          "MedDRA:10061031",
          "NANDO:2200079",
          "NCIT:C7569",
          "NCIT:C7612",
          "ONCOTREE:THYC",
          "Orphanet:99868",
          "SCTID:444374006",
          "UMLS:C0205969",
          "icd11.foundation:1351671383"
        ],
        "synonyms": [
          "carcinoma of thymus",
          "malignant thymoma",
          "thymic carcinoma",
          "thymic carcinoma (excluding well differentiated thymic carcinoma)",
          "thymic carcinoma excluding well differentiated thymic carcinoma",
          "thymoma type C",
          "thymoma, malignant",
          "thymoma, malignant (morphologic abnormality)",
          "thymoma, type C (morphologic abnormality)",
          "thymus carcinoma",
          "type C thymoma",
          "THYC"
        ],
        "categories": [
          {
            "ref": "MONDO:0005046",
            "name": "immune system disorder"
          },
          {
            "ref": "MONDO:0005151",
            "name": "endocrine system disorder"
          },
          {
            "ref": "MONDO:0005570",
            "name": "hematologic disorder"
          }
        ],
        "definition": "Thymic carcinoma (TC) is a type of thymic epithelial neoplasm characterized by a high malignant potential."
      },
      "child_count": 27,
      "reference_id": "MONDO:0006451"
    },
    {
      "id": 7959,
      "label": "thymoma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        18240
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:3275",
          "EFO:1000581",
          "GARD:0016922",
          "HP:0100522",
          "ICD9:239.89",
          "ICDO:8580/1",
          "MEDGEN:52743",
          "MESH:D013945",
          "MedDRA:10043670",
          "NCIT:C3411",
          "ONCOTREE:THYM",
          "Orphanet:99867",
          "SCTID:444231005",
          "UMLS:C0040100",
          "icd11.foundation:33869057"
        ],
        "synonyms": [
          "primary thymic epithelial neoplasm",
          "primary thymic epithelial tumor",
          "primary thymic epithelial tumour",
          "thymoma",
          "thymoma (disease)",
          "THYM"
        ],
        "categories": [
          {
            "ref": "MONDO:0005046",
            "name": "immune system disorder"
          },
          {
            "ref": "MONDO:0005151",
            "name": "endocrine system disorder"
          },
          {
            "ref": "MONDO:0005570",
            "name": "hematologic disorder"
          }
        ],
        "definition": "A neoplasm arising from the epithelial cells of the thymus. Although thymomas are usually encapsulated tumors, they may invade the capsule and infiltrate the surrounding tissues or even metastasize to distant anatomic sites. The following morphologic subtypes are currently recognized: type A, type B, type AB, metaplastic, micronodular, microscopic, and sclerosing thymoma. Thymomas type B are further subdivided into types B1, B2, and B3. Thymoma type B3 usually has the most aggressive clinical course."
      },
      "child_count": 8,
      "reference_id": "MONDO:0006456"
    },
    {
      "id": 23004,
      "label": "invasive carcinoma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6734
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "MEDGEN:233579",
          "NCIT:C9480",
          "UMLS:C1334274"
        ],
        "synonyms": [
          "invasive carcinoma"
        ],
        "definition": "A carcinoma that is not confined to the epithelium, and has spread to the surrounding stroma."
      },
      "child_count": 4,
      "reference_id": "MONDO:0040677"
    }
  ],
  "children": [],
  "roots": [
    {
      "id": 7956,
      "label": "thymic carcinoma"
    },
    {
      "id": 7959,
      "label": "thymoma"
    },
    {
      "id": 23004,
      "label": "invasive carcinoma"
    }
  ]
}