{
  "id": 4673,
  "label": "multifocal osteogenic sarcoma",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0002622",
  "properties": {
    "xrefs": [
      "DOID:3360",
      "MEDGEN:233199",
      "NCIT:C6470",
      "UMLS:C1334820"
    ],
    "synonyms": [
      "multicentric osteosarcoma",
      "multifocal osteosarcoma"
    ],
    "definition": "A primary bone osteosarcoma affecting multiple bone sites."
  },
  "isLeaf": false,
  "isRoot": false,
  "child_count": 2,
  "parents": [
    {
      "id": 11016,
      "label": "osteosarcoma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6816
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:3347",
          "EFO:0000637",
          "HP:0002669",
          "ICDO:9180/3",
          "MEDGEN:10501",
          "MESH:D012516",
          "NANDO:2200048",
          "NCIT:C9145",
          "ONCOTREE:OS",
          "UMLS:C0029463"
        ],
        "synonyms": [
          "bone tissue neoplasm",
          "osteogenic sarcoma",
          "osteoid sarcoma",
          "osteosarcoma",
          "osteosarcoma (disease)",
          "osteosarcoma, malignant",
          "sarcoma of osteoid"
        ],
        "definition": "A usually aggressive malignant bone-forming mesenchymal neoplasm, predominantly affecting adolescents and young adults. It usually involves bones and less frequently extraosseous sites. It often involves the long bones (particularly distal femur, proximal tibia, and proximal humerus). Pain with or without a palpable mass is the most frequent clinical symptom. It may spread to other anatomic sites, particularly the lungs."
      },
      "child_count": 6,
      "reference_id": "MONDO:0009807"
    }
  ],
  "children": [
    {
      "id": 5824,
      "label": "synchronous multifocal osteogenic sarcoma",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        4673
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:6696",
          "MEDGEN:236965",
          "NCIT:C6471",
          "UMLS:C1336544"
        ],
        "synonyms": [
          "synchronous multifocal osteosarcoma"
        ],
        "definition": "A bone osteosarcoma affecting multiple skeletal sites, with multifocal lesions discovered within 6 months of the appearance of the initial tumor. It has a poor prognosis."
      },
      "child_count": 0,
      "reference_id": "MONDO:0003967"
    },
    {
      "id": 5825,
      "label": "asynchronous multifocal osteogenic sarcoma",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        4673
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:6697",
          "MEDGEN:231083",
          "NCIT:C6472",
          "UMLS:C1332342"
        ],
        "synonyms": [
          "asynchronous multifocal osteosarcoma"
        ],
        "definition": "A bone osteosarcoma affecting multiple skeletal sites, with multifocal lesions discovered between 6 and 24 months after the appearance of the initial tumor. Patients with asynchronous tumors have a better prognosis than those with synchronous osteosarcomas."
      },
      "child_count": 0,
      "reference_id": "MONDO:0003968"
    }
  ],
  "roots": [
    {
      "id": 11016,
      "label": "osteosarcoma"
    }
  ]
}