{ "id": 4684, "label": "cranial nerve neoplasm", "model": { "label": "Mondo Disease Ontology (MONDO)", "source": 0 }, "type_id": 0, "reference_id": "MONDO:0002633", "properties": { "xrefs": [ "DOID:338", "ICD9:239.7", "MEDGEN:3263", "MESH:D003390", "NCIT:C2963", "SCTID:126966009", "UMLS:C0010267" ], "synonyms": [ "cranial nerve neoplasm", "cranial nerve neoplasm (disease)", "cranial nerve neoplasms", "cranial nerve tumor", "cranial nerve tumour", "neoplasm of cranial nerve", "neoplasm of the cranial nerve", "tumor of cranial nerve", "tumor of the cranial nerve", "tumour of cranial nerve", "tumour of the cranial nerve" ], "categories": [ { "ref": "MONDO:0005071", "name": "nervous system disorder" } ], "definition": "Abnormal growth of the cells that comprise the cranial nerves." }, "isLeaf": false, "isRoot": false, "child_count": 12, "parents": [ { "id": 3627, "label": "peripheral nervous system neoplasm", "isLeaf": false, "isRoot": false, "parents": [ 5512, 20456 ], "type_id": 0, "properties": { "xrefs": [ "DOID:1192", "EFO:0002431", "ICD9:239.2", "MEDGEN:45817", "MESH:D010524", "NCIT:C3321", "ONCOTREE:PNS", "SCTID:126980002", "UMLS:C0031118" ], "synonyms": [ "PNS neoplasm", "PNS neoplasms", "PNS tumor", "PNS tumour", "neoplasm of PNS", "neoplasm of peripheral nerve", "neoplasm of peripheral nervous system", "neoplasm of the PNS", "neoplasm of the peripheral nerve", "neoplasm of the peripheral nervous system", "neoplasms, PNS", "neoplasms, peripheral nervous system", "peripheral nerve neoplasm", "peripheral nerve tumor", "peripheral nerve tumour", "peripheral nervous system neoplasm", "peripheral nervous system neoplasm (disease)", "peripheral nervous system tumor", "peripheral nervous system tumour", "tumor of PNS", "tumor of peripheral nerve", "tumor of peripheral nervous system", "tumor of the PNS", "tumor of the peripheral nerve", "tumor of the peripheral nervous system", "tumour of PNS", "tumour of peripheral nerve", "tumour of peripheral nervous system", "tumour of the PNS", "tumour of the peripheral nerve", "tumour of the peripheral nervous system", "CNS-excluded nervous sys. cancer", "nerve sheath neoplasm", "nerve sheath tumors", "nerve sheath tumours" ], "categories": [ { "ref": "MONDO:0005071", "name": "nervous system disorder" } ], "definition": "A benign or malignant neoplasm arising from a peripheral nerve or the perineural sheaths." }, "child_count": 18, "reference_id": "MONDO:0001406" }, { "id": 5469, "label": "cranial nerve neuropathy", "isLeaf": false, "isRoot": false, "parents": [ 6799 ], "type_id": 0, "properties": { "xrefs": [ "DOID:5656", "ICD9:352.9", "MEDGEN:1160", "MESH:D003389", "NCIT:C26733", "SCTID:73013002", "UMLS:C0010266" ], "synonyms": [ "cranial nerve disease", "cranial nerve disorder", "cranial neuron projection bundle disease", "cranial neuron projection bundle disease or disorder", "cranial neuropathy", "disease of cranial neuron projection bundle", "disease or disorder of cranial neuron projection bundle", "disorder of cranial nerve", "disorder of cranial neuron projection bundle" ], "categories": [ { "ref": "MONDO:0005071", "name": "nervous system disorder" } ], "definition": "A neoplastic or non-neoplastic disorder that affects one of the cranial nerves." }, "child_count": 17, "reference_id": "MONDO:0003569" }, { "id": 7231, "label": "head and neck neoplasm", "isLeaf": false, "isRoot": false, "parents": [ 6798 ], "type_id": 0, "properties": { "xrefs": [ "EFO:0005950", "ICD9:239.89", "MEDGEN:6728", "NCIT:C3077", "ONCOTREE:HEADNECK", "SCTID:255055008", "UMLS:C0018671" ], "synonyms": [ "craniocervical region neoplasm", "craniocervical region neoplasm (disease)", "craniocervical region tumor", "craniocervical region tumour", "head and neck neoplasm", "head and neck neoplasm (excluding central nervous system)", "head and neck tumor", "head and neck tumour", "neoplasm of craniocervical region", "neoplasm of head and neck", "neoplasm of the head and neck", "tumor of craniocervical region", "tumor of head and neck", "tumor of the head and neck", "tumour of craniocervical region", "tumour of head and neck", "tumour of the head and neck" ], "definition": "A benign or malignant neoplasm that affects the anatomic structures of the head and neck region. Representative examples of benign neoplasms include salivary gland pleomorphic adenoma and nasal cavity papilloma. Representative examples of malignant neoplasms include oral cavity squamous cell carcinoma, laryngeal squamous cell carcinoma, and salivary gland carcinoma." }, "child_count": 37, "reference_id": "MONDO:0005586" } ], "children": [ { "id": 3641, "label": "trigeminal nerve neoplasm", "isLeaf": false, "isRoot": false, "parents": [ 4684, 5448 ], "type_id": 0, "properties": { "xrefs": [ "DOID:1201", "ICD9:239.7", "MEDGEN:226812", "NCIT:C5122", "SCTID:126971002", "UMLS:C1263897" ], "synonyms": [ "cranial nerve V neoplasms", "cranial nerve V tumors", "cranial nerve V tumours", "fifth cranial nerve neoplasm", "fifth cranial nerve tumor", "fifth cranial nerve tumour", "neoplasm of fifth cranial nerve", "neoplasm of the fifth cranial nerve", "neoplasm of the trigeminal nerve", "neoplasm of trigeminal nerve", "neoplasms, cranial nerve V", "trigeminal nerve neoplasm", "trigeminal nerve neoplasm (disease)", "trigeminal nerve neoplasms", "trigeminal nerve tumor", "trigeminal nerve tumors", "trigeminal nerve tumour", "trigeminal nerve tumours", "tumor of fifth cranial nerve", "tumor of the fifth cranial nerve", "tumor of the trigeminal nerve", "tumor of trigeminal nerve", "tumors, cranial nerve V", "tumour of fifth cranial nerve", "tumour of the fifth cranial nerve", "tumour of the trigeminal nerve", "tumour of trigeminal nerve" ], "categories": [ { "ref": "MONDO:0005071", "name": "nervous system disorder" } ], "definition": "Benign and malignant neoplasms which arise from or metastasize to the trigeminal or fifth cranial nerve which provides sensory innervation to the face, oral cavity and sinuses and the muscles of mastication. Clinical features may include facial pain or sensory loss or weakness of jaw closure." }, "child_count": 2, "reference_id": "MONDO:0001420" }, { "id": 4059, "label": "abducens nerve neoplasm", "isLeaf": true, "isRoot": false, "parents": [ 4684, 20030 ], "type_id": 0, "properties": { "xrefs": [ "DOID:14125", "ICD9:239.7", "MEDGEN:224732", "NCIT:C5826", "SCTID:126972009", "UMLS:C1263898" ], "synonyms": [ "VIth cranial nerve neoplasms", "VIth cranial nerve tumors", "VIth cranial nerve tumours", "abducens nerve neoplasm (disease)", "abducens nerve neoplasms", "abducens nerve tumor", "abducens nerve tumors", "abducens nerve tumour", "abducens nerve tumours", "neoplasm of abducens nerve", "neoplasm of sixth cranial nerve", "neoplasm of the abducens nerve", "neoplasm of the sixth cranial nerve", "sixth cranial nerve neoplasm", "sixth cranial nerve neoplasms", "sixth cranial nerve tumor", "sixth cranial nerve tumors", "sixth cranial nerve tumour", "sixth cranial nerve tumours", "tumor of abducens nerve", "tumor of sixth cranial nerve", "tumor of the abducens nerve", "tumor of the sixth cranial nerve", "tumour of abducens nerve", "tumour of sixth cranial nerve", "tumour of the abducens nerve", "tumour of the sixth cranial nerve" ], "categories": [ { "ref": "MONDO:0005071", "name": "nervous system disorder" } ], "definition": "A neoplasm involving a abducens nerve." }, "child_count": 0, "reference_id": "MONDO:0001884" }, { "id": 4238, "label": "facial nerve neoplasm", "isLeaf": true, "isRoot": false, "parents": [ 4235, 4684 ], "type_id": 0, "properties": { "xrefs": [ "DOID:1760", "ICD9:239.7", "MEDGEN:224733", "NCIT:C5827", "SCTID:126973004", "UMLS:C1263899" ], "synonyms": [ "VIIth cranial nerve neoplasms", "VIIth cranial nerve tumors", "VIIth cranial nerve tumours", "facial nerve neoplasm", "facial nerve neoplasm (disease)", "facial nerve neoplasms", "facial nerve tumor", "facial nerve tumors", "facial nerve tumour", "facial nerve tumours", "neoplasm of Facial nerve", "neoplasm of facial nerve", "neoplasm of seventh cranial nerve", "neoplasm of the Facial nerve", "neoplasm of the seventh cranial nerve", "seventh cranial nerve neoplasm", "seventh cranial nerve neoplasms", "seventh cranial nerve tumor", "seventh cranial nerve tumors", "seventh cranial nerve tumour", "seventh cranial nerve tumours", "tumor of Facial nerve", "tumor of facial nerve", "tumor of seventh cranial nerve", "tumor of the Facial nerve", "tumor of the seventh cranial nerve", "tumour of Facial nerve", "tumour of facial nerve", "tumour of seventh cranial nerve", "tumour of the Facial nerve", "tumour of the seventh cranial nerve" ], "categories": [ { "ref": "MONDO:0005071", "name": "nervous system disorder" } ], "definition": "A neoplasm involving a facial nerve." }, "child_count": 0, "reference_id": "MONDO:0002101" }, { "id": 4519, "label": "malignant cranial nerve neoplasm", "isLeaf": false, "isRoot": false, "parents": [ 4684, 7266, 20329 ], "type_id": 0, "properties": { "xrefs": [ "DOID:2815", "ICD9:192.0", "MEDGEN:57567", "NCIT:C3571", "SCTID:188307009", "UMLS:C0153644" ], "synonyms": [ "cancer of cranial nerve", "cranial nerve cancer", "cranial nerve neoplasm, malignant", "malignant cranial nerve neoplasm", "malignant cranial nerve tumor", "malignant cranial nerve tumour", "malignant neoplasm of cranial nerve", "malignant neoplasm of cranial nerves", "malignant neoplasm of the cranial nerve", "malignant tumor of cranial nerve", "malignant tumor of the cranial nerve", "malignant tumour of cranial nerve", "malignant tumour of the cranial nerve", "cranial nerve malignant neoplasm" ], "categories": [ { "ref": "MONDO:0005071", "name": "nervous system disorder" } ], "definition": "Abnormal malignant growth of the cells that comprise the cranial nerve." }, "child_count": 15, "reference_id": "MONDO:0002433" }, { "id": 4521, "label": "oculomotor nerve neoplasm", "isLeaf": false, "isRoot": false, "parents": [ 4684, 5451 ], "type_id": 0, "properties": { "xrefs": [ "DOID:2817", "ICD9:239.7", "MEDGEN:220391", "NCIT:C6994", "SCTID:126969002", "UMLS:C1263895" ], "synonyms": [ "IIIrd cranial nerve tumor", "IIIrd cranial nerve tumour", "neoplasm of oculomotor nerve", "oculomotor nerve neoplasm", "oculomotor nerve neoplasm (disease)", "oculomotor nerve tumor", "tumor of oculomotor nerve", "tumour of oculomotor nerve", "cranial nerve III tumor", "cranial nerve III tumour" ], "categories": [ { "ref": "MONDO:0005071", "name": "nervous system disorder" } ], "definition": "A neoplasm involving a oculomotor nerve." }, "child_count": 2, "reference_id": "MONDO:0002435" }, { "id": 4616, "label": "hypoglossal nerve neoplasm", "isLeaf": false, "isRoot": false, "parents": [ 3992, 4684 ], "type_id": 0, "properties": { "xrefs": [ "DOID:3198", "ICD9:239.7", "MEDGEN:220392", "NCIT:C5830", "SCTID:126978008", "UMLS:C1263903" ], "synonyms": [ "XIIth cranial nerve neoplasms", "XIIth cranial nerve tumors", "XIIth cranial nerve tumours", "hypoglossal nerve neoplasm", "hypoglossal nerve neoplasm (disease)", "hypoglossal nerve neoplasms", "hypoglossal nerve tumor", "hypoglossal nerve tumors", "hypoglossal nerve tumour", "hypoglossal nerve tumours", "neoplasm of hypoglossal nerve", "neoplasm of the hypoglossal nerve", "neoplasm of the twelfth cranial nerve", "neoplasm of twelfth cranial nerve", "tumor of hypoglossal nerve", "tumor of the hypoglossal nerve", "tumor of the twelfth cranial nerve", "tumor of twelfth cranial nerve", "tumour of hypoglossal nerve", "tumour of the hypoglossal nerve", "tumour of the twelfth cranial nerve", "tumour of twelfth cranial nerve", "twelfth cranial nerve neoplasm", "twelfth cranial nerve neoplasms", "twelfth cranial nerve tumor", "twelfth cranial nerve tumors", "twelfth cranial nerve tumour", "twelfth cranial nerve tumours" ], "categories": [ { "ref": "MONDO:0005071", "name": "nervous system disorder" } ], "definition": "A neoplasm involving a hypoglossal nerve." }, "child_count": 2, "reference_id": "MONDO:0002550" }, { "id": 4677, "label": "spinal accessory nerve neoplasm", "isLeaf": true, "isRoot": false, "parents": [ 4684, 4687 ], "type_id": 0, "properties": { "xrefs": [ "DOID:337", "ICD9:239.7", "MEDGEN:266074", "NCIT:C5829", "SCTID:126977003", "UMLS:C1263902" ], "synonyms": [ "XIth cranial nerve neoplasms", "XIth cranial nerve tumors", "XIth cranial nerve tumours", "accessory XI nerve spinal component neoplasm", "accessory XI nerve spinal component neoplasm (disease)", "accessory XI nerve spinal component tumor", "accessory XI nerve spinal component tumour", "accessory nerve neoplasm", "eleventh cranial nerve neoplasm", "eleventh cranial nerve neoplasms", "eleventh cranial nerve tumor", "eleventh cranial nerve tumors", "eleventh cranial nerve tumour", "eleventh cranial nerve tumours", "neoplasm of accessory XI nerve spinal component", "neoplasm of eleventh cranial nerve", "neoplasm of spinal accessory nerve", "neoplasm of the eleventh cranial nerve", "neoplasm of the spinal accessory nerve", "spinal accessory nerve neoplasm", "spinal accessory nerve neoplasms", "spinal accessory nerve tumor", "spinal accessory nerve tumors", "spinal accessory nerve tumour", "spinal accessory nerve tumours", "tumor of accessory XI nerve spinal component", "tumor of eleventh cranial nerve", "tumor of spinal accessory nerve", "tumor of the eleventh cranial nerve", "tumor of the spinal accessory nerve", "tumour of accessory XI nerve spinal component", "tumour of eleventh cranial nerve", "tumour of spinal accessory nerve", "tumour of the eleventh cranial nerve", "tumour of the spinal accessory nerve" ], "categories": [ { "ref": "MONDO:0005071", "name": "nervous system disorder" } ], "definition": "A neoplasm involving a accessory XI nerve spinal component." }, "child_count": 0, "reference_id": "MONDO:0002626" }, { "id": 4689, "label": "glossopharyngeal nerve neoplasm", "isLeaf": false, "isRoot": false, "parents": [ 4684, 4690 ], "type_id": 0, "properties": { "xrefs": [ "DOID:3417", "ICD9:239.7", "MEDGEN:224734", "NCIT:C5828", "SCTID:126975006", "UMLS:C1263900" ], "synonyms": [ "IXth cranial nerve neoplasms", "IXth cranial nerve tumors", "IXth cranial nerve tumours", "Ninth cranial nerve neoplasm", "Ninth cranial nerve neoplasms", "Ninth cranial nerve tumor", "Ninth cranial nerve tumors", "Ninth cranial nerve tumour", "Ninth cranial nerve tumours", "glossopharyngeal nerve neoplasm", "glossopharyngeal nerve neoplasm (disease)", "glossopharyngeal nerve neoplasms", "glossopharyngeal nerve tumor", "glossopharyngeal nerve tumors", "glossopharyngeal nerve tumour", "glossopharyngeal nerve tumours", "neoplasm of Ninth cranial nerve", "neoplasm of glossopharyngeal nerve", "neoplasm of the Ninth cranial nerve", "neoplasm of the glossopharyngeal nerve", "tumor of Ninth cranial nerve", "tumor of glossopharyngeal nerve", "tumor of the Ninth cranial nerve", "tumor of the glossopharyngeal nerve", "tumour of Ninth cranial nerve", "tumour of glossopharyngeal nerve", "tumour of the Ninth cranial nerve", "tumour of the glossopharyngeal nerve" ], "categories": [ { "ref": "MONDO:0005071", "name": "nervous system disorder" } ], "definition": "A neoplasm involving a glossopharyngeal nerve." }, "child_count": 2, "reference_id": "MONDO:0002638" }, { "id": 4691, "label": "optic nerve neoplasm", "isLeaf": false, "isRoot": false, "parents": [ 4268, 4684, 7694 ], "type_id": 0, "properties": { "xrefs": [ "DOID:3419", "EFO:1001073", "ICD9:239.7", "MEDGEN:101181", "MESH:D019574", "NCIT:C4801", "SCTID:395505000", "UMLS:C0524802" ], "synonyms": [ "cranial nerve II neoplasm", "cranial nerve II neoplasm (disease)", "cranial nerve II neoplasms", "cranial nerve II tumor", "cranial nerve II tumour", "neoplasm of cranial nerve II", "neoplasm of optic nerve", "neoplasm of second cranial nerve", "neoplasm of the optic nerve", "neoplasm of the second cranial nerve", "neoplasms, optic nerve", "neoplasms, second cranial nerve", "optic nerve neoplasm", "optic nerve neoplasms", "optic nerve tumor", "optic nerve tumour", "second cranial nerve neoplasm", "second cranial nerve neoplasms", "second cranial nerve tumor", "second cranial nerve tumour", "tumor of cranial nerve II", "tumor of optic nerve", "tumor of second cranial nerve", "tumor of the optic nerve", "tumor of the second cranial nerve", "tumour of cranial nerve II", "tumour of second cranial nerve", "tumour of the optic nerve", "tumour of the second cranial nerve" ], "categories": [ { "ref": "MONDO:0005071", "name": "nervous system disorder" }, { "ref": "MONDO:0024458", "name": "disorder of visual system" } ], "definition": "Benign and malignant neoplasms which arise from or metastasize to the optic or second cranial nerve which extends from the optic disk of the eye and joins the optic chiasm. Clinical features may include visual loss, proptosis, and local pain. The majority of optic nerve tumors or optic gliomas." }, "child_count": 9, "reference_id": "MONDO:0002640" }, { "id": 4693, "label": "trochlear nerve neoplasm", "isLeaf": true, "isRoot": false, "parents": [ 4684, 8425 ], "type_id": 0, "properties": { "xrefs": [ "DOID:3421", "ICD9:239.7", "MEDGEN:226811", "NCIT:C5825", "SCTID:126970001", "UMLS:C1263896" ], "synonyms": [ "IVth cranial nerve neoplasms", "IVth cranial nerve tumors", "IVth cranial nerve tumours", "fourth cranial nerve neoplasm", "fourth cranial nerve neoplasms", "fourth cranial nerve tumor", "fourth cranial nerve tumors", "fourth cranial nerve tumour", "fourth cranial nerve tumours", "neoplasm of fourth cranial nerve", "neoplasm of the fourth cranial nerve", "neoplasm of the trochlear nerve", "neoplasm of trochlear nerve", "trochlear nerve neoplasm (disease)", "trochlear nerve neoplasms", "trochlear nerve tumor", "trochlear nerve tumors", "trochlear nerve tumour", "trochlear nerve tumours", "tumor of fourth cranial nerve", "tumor of the fourth cranial nerve", "tumor of the trochlear nerve", "tumor of trochlear nerve", "tumour of fourth cranial nerve", "tumour of the fourth cranial nerve", "tumour of the trochlear nerve", "tumour of trochlear nerve" ], "categories": [ { "ref": "MONDO:0005071", "name": "nervous system disorder" } ], "definition": "A neoplasm involving a trochlear nerve." }, "child_count": 0, "reference_id": "MONDO:0002642" }, { "id": 4761, "label": "olfactory nerve neoplasm", "isLeaf": false, "isRoot": false, "parents": [ 4684, 4764, 20429 ], "type_id": 0, "properties": { "xrefs": [ "DOID:366", "DOID:8256", "ICD9:239.7", "MEDGEN:87551", "NCIT:C5121", "SCTID:126967000", "UMLS:C0346319" ], "synonyms": [ "cranial nerve I neoplasms", "first cranial nerve neoplasm", "first cranial nerve neoplasms", "first cranial nerve tumor", "first cranial nerve tumour", "neoplasm of first cranial nerve", "neoplasm of olfactory nerve", "neoplasm of the first cranial nerve", "neoplasm of the olfactory nerve", "neoplasms, cranial nerve I", "neoplasms, olfactory nerve", "olfactory nerve neoplasm", "olfactory nerve neoplasm (disease)", "olfactory nerve neoplasms", "olfactory nerve tumor", "olfactory nerve tumour", "olfactory neural neoplasm", "olfactory neural tumour", "tumor of first cranial nerve", "tumor of olfactory nerve", "tumor of the first cranial nerve", "tumor of the olfactory nerve", "tumour of first cranial nerve", "tumour of olfactory nerve", "tumour of the first cranial nerve", "tumour of the olfactory nerve" ], "categories": [ { "ref": "MONDO:0005071", "name": "nervous system disorder" } ], "definition": "Benign and malignant neoplasms which arise from or metastasize to the olfactory or first cranial nerve. Clinical features may include facial pain and impairments of taste or smell." }, "child_count": 3, "reference_id": "MONDO:0002722" }, { "id": 20432, "label": "vestibulocochlear nerve neoplasm", "isLeaf": false, "isRoot": false, "parents": [ 3768, 4684 ], "type_id": 0, "properties": { "xrefs": [ "MEDGEN:91099", "NCIT:C5120", "SCTID:387891008", "UMLS:C0346330" ], "synonyms": [ "Vestibuloacoustic nerve neoplasms", "acoustic nerve neoplasm", "acoustic nerve tumor", "acoustic nerve tumour", "cranial nerve eight neoplasms", "eighth cranial nerve neoplasm", "eighth cranial nerve neoplasms", "eighth cranial nerve tumor", "eighth cranial nerve tumour", "neoplasm of acoustic nerve", "neoplasm of eighth cranial nerve", "neoplasm of the acoustic nerve", "neoplasm of the eighth cranial nerve", "neoplasm of the vestibulocochlear nerve", "neoplasm of vestibulocochlear nerve", "tumor of acoustic nerve", "tumor of eighth cranial nerve", "tumor of the acoustic nerve", "tumor of the eighth cranial nerve", "tumor of the vestibulocochlear nerve", "tumor of vestibulocochlear nerve", "tumour of acoustic nerve", "tumour of eighth cranial nerve", "tumour of the acoustic nerve", "tumour of the eighth cranial nerve", "tumour of the vestibulocochlear nerve", "tumour of vestibulocochlear nerve", "vestibulocochlear nerve neoplasm (disease)", "vestibulocochlear nerve neoplasms", "vestibulocochlear nerve tumor", "vestibulocochlear nerve tumour" ], "categories": [ { "ref": "MONDO:0002409", "name": "auditory system disorder" }, { "ref": "MONDO:0005071", "name": "nervous system disorder" } ], "definition": "A neoplasm (disease) that involves the vestibulocochlear nerve." }, "child_count": 2, "reference_id": "MONDO:0021221" } ], "roots": [ { "id": 3627, "label": "peripheral nervous system neoplasm" }, { "id": 5469, "label": "cranial nerve neuropathy" }, { "id": 7231, "label": "head and neck neoplasm" } ] }