{
  "id": 4701,
  "label": "scrotal carcinoma",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0002650",
  "properties": {
    "xrefs": [
      "DOID:3445",
      "MEDGEN:235088",
      "NCIT:C6389",
      "UMLS:C1370468"
    ],
    "synonyms": [
      "cancer of scrotum",
      "cancer of the scrotum",
      "scrotal cancer",
      "carcinoma of scrotum",
      "carcinoma of the scrotum",
      "scrotum carcinoma"
    ],
    "categories": [
      {
        "ref": "MONDO:0005039",
        "name": "reproductive system disorder"
      }
    ],
    "definition": "A carcinoma that arises from epithelial cells of the scrotum."
  },
  "isLeaf": false,
  "isRoot": false,
  "child_count": 3,
  "parents": [
    {
      "id": 6734,
      "label": "carcinoma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6733,
        7265
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "CSP:2000-1867",
          "DOID:305",
          "EFO:0000313",
          "ICDO:8010/3",
          "ICDO:8011/3",
          "MEDGEN:2867",
          "MESH:D002277",
          "NCIT:C2916",
          "SCTID:722688002",
          "UMLS:C0007097"
        ],
        "synonyms": [
          "epithelioma",
          "Other carcinoma",
          "carcinoma",
          "carcinoma, malignant",
          "epithelial carcinoma",
          "epithelioma malignant",
          "malignant epithelial neoplasm",
          "malignant epithelial tumor",
          "malignant epithelial tumour",
          "malignant epithelioma"
        ],
        "definition": "A malignant tumor arising from epithelial cells. Carcinomas that arise from glandular epithelium are called adenocarcinomas, those that arise from squamous epithelium are called squamous cell carcinomas, and those that arise from transitional epithelium are called transitional cell carcinomas. Morphologically, the malignant epithelial cells may display abnormal mitotic figures, anaplasia, and necrosis. Carcinomas are graded by the degree of cellular differentiation as well, moderately, or poorly differentiated. Carcinomas invade the surrounding tissues and tend to metastasize to other anatomic sites. Lung carcinoma, skin carcinoma, breast carcinoma, colon carcinoma, and prostate carcinoma are the most frequently seen carcinomas."
      },
      "child_count": 98,
      "reference_id": "MONDO:0004993"
    },
    {
      "id": 20351,
      "label": "scrotum cancer",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        5259,
        7450
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "ICD10CM:C63.2",
          "ICD9:187.7",
          "MEDGEN:57564",
          "NCIT:C3560",
          "SCTID:363454002",
          "UMLS:C0153604"
        ],
        "synonyms": [
          "cancer of scrotum",
          "malignant neoplasm of scrotum",
          "malignant neoplasm of the scrotum",
          "malignant scrotal neoplasm",
          "malignant scrotal tumor",
          "malignant scrotal tumour",
          "malignant scrotum neoplasm",
          "malignant tumor of scrotum",
          "malignant tumor of the scrotum",
          "malignant tumour of scrotum",
          "malignant tumour of the scrotum",
          "scrotum cancer"
        ],
        "categories": [
          {
            "ref": "MONDO:0005039",
            "name": "reproductive system disorder"
          }
        ],
        "definition": "A primary or metastatic malignant neoplasm affecting the scrotum."
      },
      "child_count": 2,
      "reference_id": "MONDO:0021112"
    }
  ],
  "children": [
    {
      "id": 3847,
      "label": "scrotum squamous cell carcinoma",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        4701,
        6823
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:13159",
          "MEDGEN:138101",
          "NCIT:C4643",
          "SCTID:276860003",
          "UMLS:C0349551"
        ],
        "synonyms": [
          "scrotal squamous cell carcinoma",
          "scrotum squamous cell carcinoma",
          "squamous cell carcinoma of the scrotum",
          "squamous cell carcinoma of scrotum"
        ],
        "categories": [
          {
            "ref": "MONDO:0005039",
            "name": "reproductive system disorder"
          }
        ],
        "definition": "A rare squamous cell carcinoma that arises from the scrotum. It has been associated with exposure to environmental and industrial carcinogens. The prognosis depends on the extent of lymph node involvement."
      },
      "child_count": 0,
      "reference_id": "MONDO:0001651"
    },
    {
      "id": 4700,
      "label": "scrotum Paget disease",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        4701,
        20398
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:3444",
          "MEDGEN:65959",
          "NCIT:C7728",
          "UMLS:C0238330"
        ],
        "synonyms": [
          "Paget disease of the scrotum",
          "Paget's disease of scrotum",
          "Paget's disease of the scrotum",
          "scrotal Paget's disease",
          "scrotum Paget disease",
          "scrotum Paget's disease",
          "scrotum mammary Paget's disease"
        ],
        "categories": [
          {
            "ref": "MONDO:0005039",
            "name": "reproductive system disorder"
          }
        ],
        "definition": "A mammary Paget's disease that involves the scrotum."
      },
      "child_count": 0,
      "reference_id": "MONDO:0002649"
    },
    {
      "id": 4941,
      "label": "scrotum basal cell carcinoma",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        4701,
        7027
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:4278",
          "MEDGEN:233437",
          "NCIT:C6386",
          "UMLS:C1335934"
        ],
        "synonyms": [
          "basal cell carcinoma of scrotum",
          "basal cell scrotal carcinoma",
          "scrotal basal cell carcinoma",
          "scrotum skin basal cell carcinoma",
          "skin basal cell carcinoma of scrotum"
        ],
        "categories": [
          {
            "ref": "MONDO:0002051",
            "name": "integumentary system disorder"
          },
          {
            "ref": "MONDO:0005039",
            "name": "reproductive system disorder"
          }
        ],
        "definition": "A scrotal carcinoma that involves the basal cell."
      },
      "child_count": 0,
      "reference_id": "MONDO:0002936"
    }
  ],
  "roots": [
    {
      "id": 6734,
      "label": "carcinoma"
    },
    {
      "id": 20351,
      "label": "scrotum cancer"
    }
  ]
}