{
  "id": 4706,
  "label": "cutaneous Paget disease",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0002655",
  "properties": {
    "xrefs": [
      "DOID:3450"
    ],
    "synonyms": [
      "cutaneous Paget's disease",
      "zone of skin Paget disease"
    ],
    "categories": [
      {
        "ref": "MONDO:0002051",
        "name": "integumentary system disorder"
      }
    ],
    "definition": "A skin carcinoma that is characterized by infiltration of the skin by neoplastic large cells with abundant pale cytoplasm and large nuclei with prominent nucleoli."
  },
  "isLeaf": false,
  "isRoot": false,
  "child_count": 1,
  "parents": [
    {
      "id": 4707,
      "label": "skin carcinoma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        4907,
        6734,
        20690
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:3451",
          "EFO:0009259",
          "MEDGEN:195945",
          "NCIT:C4914",
          "UMLS:C0699893"
        ],
        "synonyms": [
          "carcinoma of skin",
          "carcinoma of the skin",
          "carcinoma of zone of skin",
          "non-melanoma cancer of skin",
          "non-melanoma cancer of the skin",
          "non-melanoma skin cancer",
          "nonmelanoma skin cancer",
          "skin cancer, non-melanoma",
          "skin carcinoma",
          "zone of skin carcinoma"
        ],
        "categories": [
          {
            "ref": "MONDO:0002051",
            "name": "integumentary system disorder"
          }
        ],
        "definition": "A carcinoma that arises from epithelial cells of the zone of skin"
      },
      "child_count": 39,
      "reference_id": "MONDO:0002656"
    },
    {
      "id": 20398,
      "label": "Paget disease",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6712
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "MEDGEN:277958",
          "NCIT:C7073",
          "UMLS:C1368019"
        ],
        "synonyms": [
          "Paget cell neoplasm",
          "Paget disease",
          "Paget's cell neoplasm",
          "Paget's disease"
        ],
        "definition": "A malignant neoplasm composed of large cells with large nuclei, prominent nucleoli, and abundant pale cytoplasm (Paget cells). Paget cell neoplasms include Paget disease of the nipple and extramammary Paget disease which may affect the vulva, penis, anus, skin and scrotum."
      },
      "child_count": 5,
      "reference_id": "MONDO:0021165"
    }
  ],
  "children": [
    {
      "id": 6153,
      "label": "perianal skin Paget disease",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        4702,
        4706,
        4946
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:7708",
          "GARD:0023944",
          "MEDGEN:231372",
          "NCIT:C7476",
          "UMLS:C1332270"
        ],
        "synonyms": [
          "Paget disease of the anal margin",
          "Paget's disease of the anal margin",
          "anal margin Paget's disease",
          "perianal skin Paget disease",
          "perianal skin Paget's disease",
          "perianal skin mammary Paget's disease"
        ],
        "categories": [
          {
            "ref": "MONDO:0002051",
            "name": "integumentary system disorder"
          },
          {
            "ref": "MONDO:0004335",
            "name": "digestive system disorder"
          }
        ],
        "definition": "Paget disease involving the perianal skin."
      },
      "child_count": 0,
      "reference_id": "MONDO:0004337"
    }
  ],
  "roots": [
    {
      "id": 4707,
      "label": "skin carcinoma"
    },
    {
      "id": 20398,
      "label": "Paget disease"
    }
  ]
}