{
  "id": 4717,
  "label": "ampullary signet ring cell adenocarcinoma",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0002669",
  "properties": {
    "xrefs": [
      "DOID:3501",
      "GARD:0023207",
      "MEDGEN:231057",
      "NCIT:C6656",
      "UMLS:C1332249"
    ],
    "synonyms": [
      "ampulla of Vater signet Ring cell carcinoma",
      "ampullary signet Ring cell carcinoma",
      "ampullary signet ring cell carcinoma"
    ],
    "categories": [
      {
        "ref": "MONDO:0004335",
        "name": "digestive system disorder"
      },
      {
        "ref": "MONDO:0005151",
        "name": "endocrine system disorder"
      }
    ],
    "definition": "An adenocarcinoma arising from the ampulla of Vater. Morphologically, it is characterized by the presence of mucin-containing signet-ring cells."
  },
  "isLeaf": true,
  "isRoot": false,
  "child_count": 0,
  "parents": [
    {
      "id": 4713,
      "label": "extrahepatic bile duct signet ring cell carcinoma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        4714,
        6819
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:3494",
          "GARD:0023204",
          "MEDGEN:163667",
          "NCIT:C5776",
          "UMLS:C0861859"
        ],
        "synonyms": [
          "bile duct signet Ring cell carcinoma",
          "bile duct signet ring cell carcinoma",
          "extrahepatic bile duct signet Ring cell carcinoma",
          "signet Ring cell bile duct carcinoma",
          "signet Ring cell carcinoma of bile duct",
          "signet Ring cell carcinoma of the bile duct"
        ],
        "categories": [
          {
            "ref": "MONDO:0004335",
            "name": "digestive system disorder"
          },
          {
            "ref": "MONDO:0005151",
            "name": "endocrine system disorder"
          }
        ],
        "definition": "An adenocarcinoma that arises from the extrahepatic bile ducts. It is characterized by the presence of signet ring malignant epithelial cells."
      },
      "child_count": 4,
      "reference_id": "MONDO:0002664"
    },
    {
      "id": 4718,
      "label": "ampulla of vater adenocarcinoma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        4714,
        7742,
        17870
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:3502",
          "EFO:0008490",
          "GARD:0023208",
          "MEDGEN:231054",
          "NCIT:C6650",
          "UMLS:C1332243",
          "icd11.foundation:1601321941"
        ],
        "synonyms": [
          "adenocarcinoma of ampulla of Vater",
          "ampulla of Vater adenocarcinoma",
          "ampullary adenocarcinoma",
          "hepatopancreatic ampulla adenocarcinoma",
          "invasive adenocarcinoma of the ampullary region"
        ],
        "categories": [
          {
            "ref": "MONDO:0004335",
            "name": "digestive system disorder"
          },
          {
            "ref": "MONDO:0005151",
            "name": "endocrine system disorder"
          }
        ],
        "definition": "A carcinoma that arises from glandular epithelial cells of the hepatopancreatic ampulla"
      },
      "child_count": 12,
      "reference_id": "MONDO:0002670"
    }
  ],
  "children": [],
  "roots": [
    {
      "id": 4713,
      "label": "extrahepatic bile duct signet ring cell carcinoma"
    },
    {
      "id": 4718,
      "label": "ampulla of vater adenocarcinoma"
    }
  ]
}