{
  "id": 4720,
  "label": "acinar prostate adenocarcinoma, signet ring variant",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0002672",
  "properties": {
    "xrefs": [
      "DOID:3504",
      "GARD:0027611",
      "MEDGEN:1835069",
      "NCIT:C5535",
      "UMLS:C5787291"
    ],
    "synonyms": [
      "acinar prostate adenocarcinoma, signet Ring variant",
      "prostate gland signet ring cell carcinoma",
      "signet Ring cell carcinoma of the prostate",
      "prostate signet ring cell adenocarcinoma"
    ],
    "categories": [
      {
        "ref": "MONDO:0005039",
        "name": "reproductive system disorder"
      }
    ],
    "definition": "A morphologic variant of acinar adenocarcinoma of the prostate gland characterized by the presence of signet ring malignant cells."
  },
  "isLeaf": true,
  "isRoot": false,
  "child_count": 0,
  "parents": [
    {
      "id": 4572,
      "label": "prostatic acinar adenocarcinoma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6708,
        6810
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:3024",
          "GARD:0027608",
          "MEDGEN:231350",
          "NCIT:C5596",
          "UMLS:C1332139"
        ],
        "synonyms": [
          "acinar adenocarcinoma of prostate",
          "acinar adenocarcinoma of the prostate",
          "acinar prostate adenocarcinoma",
          "prostate acinar adenocarcinoma",
          "prostatic acinar adenocarcinoma"
        ],
        "categories": [
          {
            "ref": "MONDO:0005039",
            "name": "reproductive system disorder"
          }
        ],
        "definition": "An invasive adenocarcinoma of the prostate gland composed of secretory cells. It is the most common histologic type of prostate adenocarcinoma. Several morphologic variants exist, including atrophic, pseudohyperplastic, foamy gland, and oncocytic variants."
      },
      "child_count": 8,
      "reference_id": "MONDO:0002493"
    },
    {
      "id": 6819,
      "label": "signet ring cell carcinoma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6712
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:3493",
          "EFO:0000698",
          "ICDO:8490/3",
          "MEDGEN:61663",
          "MESH:D018279",
          "NCIT:C3774",
          "UMLS:C0206696"
        ],
        "synonyms": [
          "signet ring carcinoma NOS (morphologic abnormality)",
          "signet ring cell adenocarcinoma",
          "signet ring cell carcinoma",
          "signet ring cell carcinoma (morphologic abnormality)"
        ],
        "definition": "A usually aggressive, poorly differentiated invasive adenocarcinoma characterized by the presence of malignant glandular cells in which the nucleus is pressed to one side by the presence of intracytoplasmic mucus. It may arise from the stomach, small and large intestine, ampulla of Vater, appendix, gallbladder, pancreas, lung, bladder, breast, and prostate gland."
      },
      "child_count": 11,
      "reference_id": "MONDO:0005092"
    }
  ],
  "children": [],
  "roots": [
    {
      "id": 4572,
      "label": "prostatic acinar adenocarcinoma"
    },
    {
      "id": 6819,
      "label": "signet ring cell carcinoma"
    }
  ]
}