{
  "id": 4726,
  "label": "cerebral infarction",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0002679",
  "properties": {
    "xrefs": [
      "DOID:3526",
      "ICD10CM:I63",
      "ICD10CM:I63.9",
      "ICD10WHO:I63",
      "ICD9:433.01",
      "ICD9:433.21",
      "ICD9:433.31",
      "ICD9:433.81",
      "ICD9:434.91",
      "MEDGEN:3321",
      "MESH:D002544",
      "NCIT:C50486",
      "SCTID:432504007",
      "UMLS:C0007785",
      "icd11.foundation:1614716959",
      "icd11.foundation:636274910"
    ],
    "synonyms": [
      "CVA - cerebral infarction",
      "brain infarction of telencephalon",
      "cerebral infarct",
      "cerebral infarction",
      "cerebral ischemia",
      "cerebral, infarction",
      "infarction, cerebral",
      "telencephalon brain infarction"
    ],
    "categories": [
      {
        "ref": "MONDO:0004995",
        "name": "cardiovascular disorder"
      },
      {
        "ref": "MONDO:0005071",
        "name": "nervous system disorder"
      }
    ],
    "definition": "An ischemic condition of the brain, producing a persistent focal neurological deficit in the area of distribution of the cerebral arteries."
  },
  "isLeaf": false,
  "isRoot": false,
  "child_count": 4,
  "parents": [
    {
      "id": 7072,
      "label": "brain infarction",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        12183
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:3454",
          "EFO:0004277",
          "MEDGEN:148426",
          "MESH:D020520",
          "UMLS:C0751955"
        ],
        "categories": [
          {
            "ref": "MONDO:0004995",
            "name": "cardiovascular disorder"
          },
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "Tissue necrosis in any area of the brain, including the cerebral hemispheres, the cerebellum, and the brain stem. Brain infarction is the result of a cascade of events initiated by inadequate blood flow through the brain that is followed by hypoxia and hypoglycemia in brain tissue. Damage may be temporary, permanent, selective or pan-necrosis."
      },
      "child_count": 3,
      "reference_id": "MONDO:0005394"
    },
    {
      "id": 29356,
      "label": "ischemic stroke",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6825
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0051062",
          "MEDGEN:215292",
          "UMLS:C0948008"
        ],
        "synonyms": [
          "ischaemic stroke"
        ],
        "categories": [
          {
            "ref": "MONDO:0004995",
            "name": "cardiovascular disorder"
          },
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "A stroke disorder caused by obstruction of blood flow to the brain, due to thrombotic (local blood clot formation) or embolic (due to a blood clot or other material traveling from another site) event."
      },
      "child_count": 5,
      "reference_id": "MONDO:1060198"
    }
  ],
  "children": [
    {
      "id": 8119,
      "label": "anterior cerebral artery infarction",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        4726
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:3528",
          "EFO:1000807",
          "MEDGEN:148402",
          "MESH:D020243",
          "UMLS:C0751843"
        ],
        "categories": [
          {
            "ref": "MONDO:0004995",
            "name": "cardiovascular disorder"
          },
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "Necrosis occurring in the anterior cerebral artery system, including branches such as Heubner's artery. These arteries supply blood to the medial and superior parts of the cerebral hemisphere, Infarction in the anterior cerebral artery usually results in sensory and motor impairment in the lower body."
      },
      "child_count": 0,
      "reference_id": "MONDO:0006647"
    },
    {
      "id": 8300,
      "label": "middle cerebral artery infarction",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        4726,
        8158
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:3525",
          "EFO:1001045",
          "MEDGEN:152845",
          "MESH:D020244",
          "UMLS:C0740392"
        ],
        "categories": [
          {
            "ref": "MONDO:0004995",
            "name": "cardiovascular disorder"
          },
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "Necrosis occurring in the middle cerebral artery distribution system which brings blood to the entire lateral aspects of each cerebral hemisphere. Clinical signs include impaired cognition; aphasia; agraphia; weak and numbness in the face and arms, contralaterally or bilaterally depending on the infarction."
      },
      "child_count": 0,
      "reference_id": "MONDO:0006857"
    },
    {
      "id": 8350,
      "label": "posterior cerebral artery infarction",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        4726,
        8158
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:3821",
          "EFO:1001118",
          "MEDGEN:199818",
          "MESH:D020762",
          "UMLS:C0752132"
        ],
        "categories": [
          {
            "ref": "MONDO:0004995",
            "name": "cardiovascular disorder"
          },
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "Necrosis induced by ischemia in the posterior cerebral artery distribution system which supplies portions of the brain stem; the thalamus; temporal lobe, and occipital lobe. Depending on the size and location of infarction, clinical features include olfaction disorders and visual problems (agnosia; alexia; hemianopsia)."
      },
      "child_count": 0,
      "reference_id": "MONDO:0006917"
    },
    {
      "id": 23167,
      "label": "multi-infarct dementia",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        4726,
        6434
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "MEDGEN:8277",
          "MESH:D015161",
          "NCIT:C34522",
          "SCTID:56267009",
          "UMLS:C0011263",
          "icd11.foundation:645643099"
        ],
        "synonyms": [
          "multi infarct dementia",
          "multi-infarct dementia",
          "Binswanger disease",
          "Binswanger's disease",
          "Dementias, Multiinfarct",
          "Dementias, lacunar",
          "Dementias, multi-infarct",
          "Multiinfarct Dementias",
          "Multiinfarct dementia",
          "arteriosclerotic dementia",
          "dementia multi infarct",
          "dementia multi-infarct",
          "dementia multi-infarcts",
          "dementia, Multiinfarct",
          "dementia, lacunar",
          "dementia, multi infarct",
          "lacunar Dementias",
          "lacunar dementia",
          "multi-infarct Dementias",
          "multi-infarct, dementia",
          "multi-infarcts, dementia"
        ],
        "categories": [
          {
            "ref": "MONDO:0004995",
            "name": "cardiovascular disorder"
          },
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "A common form of dementia caused by multiple cortical or subcortical cerebral infarctions."
      },
      "child_count": 0,
      "reference_id": "MONDO:0043224"
    }
  ],
  "roots": [
    {
      "id": 7072,
      "label": "brain infarction"
    },
    {
      "id": 29356,
      "label": "ischemic stroke"
    }
  ]
}