{
  "id": 4732,
  "label": "childhood choroid plexus carcinoma",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0002685",
  "properties": {
    "xrefs": [
      "DOID:3545",
      "GARD:0023214",
      "MEDGEN:901899",
      "NCIT:C124292",
      "UMLS:C1510426"
    ],
    "synonyms": [
      "childhood choroid plexus neoplasm",
      "childhood choroid plexus carcinoma",
      "choroid plexus carcinoma of childhood",
      "paediatric choroid plexus carcinoma",
      "pediatric choroid plexus carcinoma",
      "childhood choroid plexus cancer"
    ],
    "categories": [
      {
        "ref": "MONDO:0004995",
        "name": "cardiovascular disorder"
      },
      {
        "ref": "MONDO:0005071",
        "name": "nervous system disorder"
      }
    ],
    "definition": "A choroid plexus carcinoma that occurs during childhood."
  },
  "isLeaf": true,
  "isRoot": false,
  "child_count": 0,
  "parents": [
    {
      "id": 4214,
      "label": "supratentorial cancer",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        3853
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:1659",
          "GARD:0027597",
          "MEDGEN:155589",
          "MESH:D015173",
          "NCIT:C4964",
          "UMLS:C0751589"
        ],
        "synonyms": [
          "malignant supratentorial neoplasm",
          "malignant supratentorial tumor",
          "malignant supratentorial tumour",
          "supratentorial neoplasms, malignant"
        ],
        "categories": [
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "Primary and metastatic (secondary) tumors of the brain located above the tentorium cerebelli, a fold of dura mater separating the CEREBELLUM and brain STEM from the cerebral hemispheres and DIENCEPHALON (i.e., THALAMUS and HYPOTHALAMUS and related structures). In adults, primary neoplasms tend to arise in the supratentorial compartment, whereas in children they occur more frequently in the infratentorial space. Clinical manifestations vary with the location of the lesion, but SEIZURES; APHASIA; HEMIANOPSIA; hemiparesis; and sensory deficits are relatively common features. Metastatic supratentorial neoplasms are frequently multiple at the time of presentation."
      },
      "child_count": 4,
      "reference_id": "MONDO:0002071"
    },
    {
      "id": 8005,
      "label": "childhood malignant neoplasm",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6733,
        20320
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "EFO:1000654",
          "MEDGEN:82962",
          "NCIT:C4005",
          "UMLS:C0278704"
        ],
        "synonyms": [
          "childhood cancer",
          "childhood malignant neoplasm",
          "childhood neoplasm, malignant",
          "malignant childhood neoplasm",
          "malignant childhood tumor",
          "malignant childhood tumour",
          "malignant paediatric neoplasm",
          "malignant paediatric tumour",
          "malignant pediatric neoplasm",
          "malignant pediatric tumor",
          "paediatric cancer",
          "pediatric cancer",
          "malignant neoplasm"
        ],
        "definition": "A malignant tumor that occurs in children. Representative examples include soft tissue and bone sarcomas (e.g. osteosarcoma) and embryonal neoplasms (e.g. hepatoblastoma and rhabdoid tumor)."
      },
      "child_count": 60,
      "reference_id": "MONDO:0006517"
    },
    {
      "id": 17176,
      "label": "choroid plexus carcinoma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        4728,
        6734
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:5648",
          "GARD:0008238",
          "ICDO:9390/3",
          "MEDGEN:96557",
          "MESH:C562943",
          "MedDRA:10067478",
          "NCIT:C4715",
          "ONCOTREE:CPC",
          "Orphanet:251899",
          "SCTID:188292007",
          "UMLS:C0431109",
          "icd11.foundation:1128449352"
        ],
        "synonyms": [
          "cancer of choroid plexus",
          "cancer of the choroid plexus",
          "choroid plexus cancer",
          "malignant neoplasm of choroid plexus",
          "malignant neoplasm of the choroid plexus",
          "malignant tumor of choroid plexus",
          "malignant tumour of choroid plexus",
          "anaplastic choroid plexus papilloma",
          "carcinoma of choroid plexus",
          "carcinoma of the choroid plexus",
          "carcinoma, choroid plexus, malignant",
          "choroid plexus carcinoma",
          "choroid plexus carcinoma (morphologic abnormality)"
        ],
        "categories": [
          {
            "ref": "MONDO:0004995",
            "name": "cardiovascular disorder"
          },
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "A malignant neoplasm arising from the choroid plexus. It shows anaplastic features and usually invades neighboring brain structures. Cerebrospinal fluid metastases are frequent. (Adapted from WHO)"
      },
      "child_count": 2,
      "reference_id": "MONDO:0016718"
    },
    {
      "id": 21583,
      "label": "childhood choroid plexus neoplasm",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        17175,
        20320
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0025460",
          "MEDGEN:76132",
          "NCIT:C42080",
          "UMLS:C0280623"
        ],
        "synonyms": [
          "choroid plexus neoplasm",
          "childhood choroid plexus neoplasm",
          "choroid plexus neoplasm of childhood",
          "paediatric choroid plexus neoplasm",
          "pediatric choroid plexus neoplasm"
        ],
        "categories": [
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "A neoplasm that arises from the choroid plexus in the brain and occurs during childhood."
      },
      "child_count": 2,
      "reference_id": "MONDO:0024744"
    }
  ],
  "children": [],
  "roots": [
    {
      "id": 4214,
      "label": "supratentorial cancer"
    },
    {
      "id": 8005,
      "label": "childhood malignant neoplasm"
    },
    {
      "id": 17176,
      "label": "choroid plexus carcinoma"
    },
    {
      "id": 21583,
      "label": "childhood choroid plexus neoplasm"
    }
  ]
}