{
  "id": 4733,
  "label": "superior mesenteric artery syndrome",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0002687",
  "properties": {
    "xrefs": [
      "DOID:3557",
      "GARD:0007712",
      "MEDGEN:21404",
      "MESH:D013478",
      "NCIT:C85175",
      "NORD:1955",
      "Orphanet:622099",
      "SCTID:197006009",
      "UMLS:C0038828"
    ],
    "synonyms": [
      "superior mesenteric artery syndrome",
      "superior mesenteric artery syndromic disease",
      "syndromic disease of superior mesenteric artery",
      "Arteriomesenteric duodenal compression syndrome",
      "Cast syndrome",
      "Wilkie syndrome",
      "vascular compression of the duodenum"
    ],
    "categories": [
      {
        "ref": "MONDO:0002254",
        "name": "syndromic disease"
      },
      {
        "ref": "MONDO:0004335",
        "name": "digestive system disorder"
      },
      {
        "ref": "MONDO:0004995",
        "name": "cardiovascular disorder"
      }
    ],
    "definition": "Superior mesenteric artery syndrome (SMAS) is a digestive condition that occurs when the duodenum (the first part of the small intestine) is compressed between two arteries (the aorta and the superior mesenteric artery). This compression causes partial or complete blockage of the duodenum. Symptoms vary based on severity, but can be severely debilitating. Symptoms may include abdominal pain, fullness, nausea, vomiting, and/or weight loss. SMAS typically is due toloss of the mesenteric fat pad (fatty tissue that surrounds the superior mesenteric artery). The most common cause is significant weight loss caused by medical disorders, psychological disorders, or surgery. In younger patients, it most commonly occurs after corrective spinal surgery for scoliosis. Delays in diagnosis may result in significant complications. Depending on the cause and severity, treatment options may include addressing the underlying cause, dietary changes (small feedings or a liquid diet), and/or surgery. Symptoms may not resolve completely after treatment."
  },
  "isLeaf": true,
  "isRoot": false,
  "child_count": 0,
  "parents": [
    {
      "id": 4370,
      "label": "syndromic disease",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        29379
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:225",
          "MEDGEN:11688",
          "MESH:D013577",
          "NCIT:C28193",
          "OGMS:0000086",
          "UMLS:C0039082"
        ],
        "synonyms": [
          "cluster, symptom",
          "clusters, symptom",
          "symptom cluster",
          "symptom clusters",
          "syndrome",
          "syndrome associated with disease or disorder",
          "syndromes",
          "syndromic disease",
          "syndromic disease or disorder"
        ],
        "categories": [
          {
            "ref": "MONDO:0002254",
            "name": "syndromic disease"
          }
        ],
        "definition": "A group of signs, symptoms, and clinicopathological characteristics that may or may not have a genetic basis and collectively define an abnormal condition."
      },
      "child_count": 1182,
      "reference_id": "MONDO:0002254"
    },
    {
      "id": 4734,
      "label": "duodenal obstruction",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        4880,
        6363
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:3558",
          "MEDGEN:4417",
          "MESH:D004380",
          "SCTID:95532008",
          "UMLS:C0013292",
          "icd11.foundation:1450844990"
        ],
        "categories": [
          {
            "ref": "MONDO:0004335",
            "name": "digestive system disorder"
          }
        ],
        "definition": "Blockage of the normal flow of stomach contents through the duodenum."
      },
      "child_count": 6,
      "reference_id": "MONDO:0002688"
    },
    {
      "id": 7210,
      "label": "aortic disorder",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        2933
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:520",
          "EFO:0005775",
          "ICD9:447.9",
          "MEDGEN:1618",
          "MESH:D001018",
          "NCIT:C101253",
          "SCTID:47040006",
          "UMLS:C0003493"
        ],
        "synonyms": [
          "aorta disease",
          "aorta disease or disorder",
          "disease of aorta",
          "disease or disorder of aorta",
          "disorder of aorta"
        ],
        "categories": [
          {
            "ref": "MONDO:0004995",
            "name": "cardiovascular disorder"
          }
        ],
        "definition": "Pathology involving the thoracic, thoracoabdominal, or abdominal aorta (including aneurysms). (ACC)"
      },
      "child_count": 17,
      "reference_id": "MONDO:0005561"
    }
  ],
  "children": [],
  "roots": [
    {
      "id": 4370,
      "label": "syndromic disease"
    },
    {
      "id": 4734,
      "label": "duodenal obstruction"
    },
    {
      "id": 7210,
      "label": "aortic disorder"
    }
  ]
}