{
  "id": 4740,
  "label": "Sertoli cell tumor",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0002696",
  "properties": {
    "xrefs": [
      "DOID:3577",
      "ICDO:8630/1",
      "ICDO:8640/1",
      "MEDGEN:11387",
      "MESH:D012707",
      "NCIT:C39976",
      "UMLS:C0036769"
    ],
    "synonyms": [
      "Sertoli cell tumor",
      "tubular androblastoma NOS (morphologic abnormality)"
    ],
    "categories": [
      {
        "ref": "MONDO:0005039",
        "name": "reproductive system disorder"
      }
    ],
    "definition": "A sex cord-stromal tumor of the testis or the ovary. It is characterized by the presence of Sertoli cells forming tubules. Leydig cells are rare or absent. It may be associated with Peutz-Jeghers syndrome. In males, the presenting symptom is a slow growing testicular mass. Most cases follow a benign clinical course. In females it may present with estrogenic or androgenic manifestations. The vast majority of cases have a benign clinical course."
  },
  "isLeaf": false,
  "isRoot": false,
  "child_count": 3,
  "parents": [
    {
      "id": 7639,
      "label": "sex cord-stromal tumor",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        7638
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:192",
          "EFO:1000052",
          "ICDO:8590/1",
          "MEDGEN:104926",
          "NANDO:2200072",
          "NCIT:C3794",
          "UMLS:C0206724"
        ],
        "synonyms": [
          "Sex cord stromal tumor",
          "Sex cord-stromal neoplasm",
          "Sex cord-stromal tumor",
          "Sex cord-stromal tumor, no ICD-O subtype",
          "Sex cord-stromal tumor, no ICD-O subtype (morphologic abnormality)",
          "Sex cord-stromal tumour",
          "neoplasm of sex cord",
          "sex cord neoplasm",
          "sex cord tumor",
          "sex cord tumour",
          "sex cord-stromal tumor",
          "specialised gonadal neoplasm",
          "specialised gonadal neoplasm (morphologic abnormality)",
          "specialised gonadal neoplasm NOS (morphologic abnormality)",
          "specialised gonadal tumour",
          "specialised gonadal tumour (qualifier value)",
          "specialized gonadal neoplasm (morphologic abnormality)",
          "specialized gonadal neoplasm NOS (morphologic abnormality)",
          "specialized gonadal tumor (qualifier value)",
          "tumor of sex cord",
          "tumour of sex cord",
          "malignant testicular sex cord-stromal tumor",
          "malignant testicular sex cord-stromal tumour"
        ],
        "categories": [
          {
            "ref": "MONDO:0005039",
            "name": "reproductive system disorder"
          }
        ],
        "definition": "A neoplasm involving a sex cord."
      },
      "child_count": 9,
      "reference_id": "MONDO:0006055"
    }
  ],
  "children": [
    {
      "id": 2877,
      "label": "malignant Sertoli cell tumor",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        4279,
        4740
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0050617",
          "ICDO:8630/3",
          "ICDO:8640/3",
          "MEDGEN:137755",
          "NCIT:C67006",
          "UMLS:C0334406"
        ],
        "synonyms": [
          "Sertoli cell tumor, malignant",
          "malignant Androblastoma"
        ],
        "categories": [
          {
            "ref": "MONDO:0005039",
            "name": "reproductive system disorder"
          }
        ],
        "definition": "A Sertoli cell tumor of the testis or the ovary which metastasizes to another anatomic site."
      },
      "child_count": 0,
      "reference_id": "MONDO:0000378"
    },
    {
      "id": 20205,
      "label": "testicular sertoli cell tumor",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        4740,
        5102
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0025254",
          "MEDGEN:91165",
          "NCIT:C4672",
          "UMLS:C0349671"
        ],
        "synonyms": [
          "Sertoli Cell Neoplasm of Testis",
          "Sertoli Cell Neoplasm of the Testis",
          "Sertoli Cell Tumor of Testis",
          "Sertoli Cell Tumor of the Testis",
          "Sertoli Cell Tumour of Testis",
          "Sertoli Cell Tumour of the Testis",
          "Testicular Sertoli Cell Neoplasm",
          "Testicular Sertoli Cell Tumor",
          "Testicular Sertoli Cell Tumor, NOS",
          "Testicular Sertoli Cell Tumor, Not Otherwise Specified",
          "Testicular Sertoli Cell Tumour"
        ],
        "categories": [
          {
            "ref": "MONDO:0005039",
            "name": "reproductive system disorder"
          },
          {
            "ref": "MONDO:0005151",
            "name": "endocrine system disorder"
          }
        ],
        "definition": "A sex cord-stromal tumor that arises from the testis and is characterized by the presence of neoplastic cells with features of Sertoli cells. It usually presents as a slow growing testicular mass. The vast majority of cases follow a benign clinical course."
      },
      "child_count": 2,
      "reference_id": "MONDO:0020808"
    },
    {
      "id": 20206,
      "label": "benign sertoli cell tumor",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        4740,
        21634
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "ICDO:8630/0",
          "MEDGEN:361204",
          "NCIT:C67012",
          "UMLS:C1879826"
        ],
        "synonyms": [
          "Benign Androblastoma",
          "Benign Sertoli Cell Tumor",
          "Benign Sertoli Cell Tumour",
          "SERTOLI CELL TUMOR, BENIGN"
        ],
        "categories": [
          {
            "ref": "MONDO:0005039",
            "name": "reproductive system disorder"
          }
        ],
        "definition": "A Sertoli cell tumor of the testis or the ovary which remains localized and does not metastasize to another anatomic site."
      },
      "child_count": 2,
      "reference_id": "MONDO:0020809"
    }
  ],
  "roots": [
    {
      "id": 7639,
      "label": "sex cord-stromal tumor"
    }
  ]
}