{
  "id": 4783,
  "label": "rectum mucinous adenocarcinoma",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0002748",
  "properties": {
    "xrefs": [
      "DOID:3709",
      "MEDGEN:83537",
      "NCIT:C7973",
      "UMLS:C0279652"
    ],
    "synonyms": [
      "colloid adenocarcinoma of rectum",
      "colloid adenocarcinoma of the rectum",
      "colloidal adenocarcinoma of rectum",
      "colloidal adenocarcinoma of the rectum",
      "mucinous adenocarcinoma of rectum",
      "mucinous adenocarcinoma of the rectum",
      "rectal colloid adenocarcinoma",
      "rectal colloidal adenocarcinoma",
      "rectal mucinous adenocarcinoma",
      "rectum mucinous adenocarcinoma"
    ],
    "categories": [
      {
        "ref": "MONDO:0004335",
        "name": "digestive system disorder"
      }
    ],
    "definition": "An invasive adenocarcinoma of the rectum characterized by the presence of pools of extracellular mucin. Malignant glandular epithelial cells are present in the mucin collections. Mucin constitutes more than 50% of the lesion."
  },
  "isLeaf": false,
  "isRoot": false,
  "child_count": 1,
  "parents": [
    {
      "id": 4295,
      "label": "rectum adenocarcinoma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6746,
        23485
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:1996",
          "EFO:0005631",
          "MEDGEN:56214",
          "NCIT:C9383",
          "ONCOTREE:READ",
          "SCTID:254582000",
          "UMLS:C0149978",
          "icd11.foundation:1316028436"
        ],
        "synonyms": [
          "adenocarcinoma - rectum",
          "adenocarcinoma of rectum",
          "adenocarcinoma of the rectum",
          "rectal adenocarcinoma",
          "rectum adenocarcinoma",
          "read"
        ],
        "categories": [
          {
            "ref": "MONDO:0004335",
            "name": "digestive system disorder"
          }
        ],
        "definition": "An adenocarcinoma arising from the rectum. It is more frequently seen in populations with a Western type diet and in patients with a history of chronic inflammatory bowel disease. Signs and symptoms include intestinal bleeding, anemia, and change in bowel habits. According to the degree of cellular differentiation, rectal adenocarcinomas are divided into well, moderately, and poorly differentiated. Histologic variants include mucinous adenocarcinoma, signet ring cell carcinoma, medullary carcinoma, serrated adenocarcinoma, cribriform comedo-type adenocarcinoma, and micropapillary adenocarcinoma."
      },
      "child_count": 8,
      "reference_id": "MONDO:0002169"
    },
    {
      "id": 6700,
      "label": "mucinous adenocarcinoma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6712,
        20031
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:3030",
          "EFO:0000197",
          "ICDO:8480/3",
          "MEDGEN:2844",
          "MESH:D002288",
          "NCIT:C26712",
          "ONCOTREE:CEMU",
          "UMLS:C0007130",
          "icd11.foundation:529352875"
        ],
        "synonyms": [
          "adenocarcinoma, mucinous, malignant",
          "colloid adenocarcinoma",
          "colloid carcinoma",
          "gelatinous adenocarcinoma",
          "gelatinous carcinoma",
          "mucin-producing adenocarcinoma (morphologic abnormality)",
          "mucinous adenocarcinoma",
          "mucinous carcinoma",
          "mucinuos carcinoma",
          "mucoid adenocarcinoma",
          "mucoid carcinoma",
          "mucous adenocarcinoma",
          "mucous carcinoma",
          "CEMU"
        ],
        "definition": "An invasive adenocarcinoma composed of malignant glandular cells which contain intracytoplasmic mucin. Often, the infiltrating glandular structures are associated with mucoid stromal formation. It may arise from the large and small intestine, appendix, stomach, lung, ovary, breast, corpus uteri, cervix, vagina, and salivary gland."
      },
      "child_count": 34,
      "reference_id": "MONDO:0004957"
    }
  ],
  "children": [
    {
      "id": 4770,
      "label": "anal mucinous adenocarcinoma",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        4703,
        4783
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:3691",
          "GARD:0027616",
          "MEDGEN:233980",
          "NCIT:C5606",
          "UMLS:C1332272"
        ],
        "synonyms": [
          "anal colloid adenocarcinoma",
          "anal colloidal adenocarcinoma",
          "anal mucinous adenocarcinoma",
          "anus mucinous adenocarcinoma",
          "colloid adenocarcinoma of anus",
          "colloid adenocarcinoma of the anus",
          "colloidal adenocarcinoma of anus",
          "colloidal adenocarcinoma of the anus",
          "mucinous adenocarcinoma of anus",
          "mucinous adenocarcinoma of the anus"
        ],
        "categories": [
          {
            "ref": "MONDO:0004335",
            "name": "digestive system disorder"
          }
        ],
        "definition": "An anal adenocarcinoma characterized by the presence of mucoid stroma formation."
      },
      "child_count": 0,
      "reference_id": "MONDO:0002734"
    }
  ],
  "roots": [
    {
      "id": 4295,
      "label": "rectum adenocarcinoma"
    },
    {
      "id": 6700,
      "label": "mucinous adenocarcinoma"
    }
  ]
}