{
  "id": 4788,
  "label": "extramedullary plasmacytoma",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0002754",
  "properties": {
    "xrefs": [
      "DOID:3720",
      "GARD:0023233",
      "ICD10CM:C90.2",
      "ICD9:203.80",
      "ICDO:9734/3",
      "MEDGEN:75843",
      "NCIT:C4002",
      "ONCOTREE:EP",
      "SCTID:188718006",
      "UMLS:C0278619",
      "icd11.foundation:246947217"
    ],
    "synonyms": [
      "extramedullary plasmacytoma",
      "extramedullary plasmacytoma (clinical)",
      "extraosseous plasmacytoma",
      "plasmacytoma, extramedullary",
      "plasmacytoma, extramedullary (not occurring in bone)",
      "EP"
    ],
    "categories": [
      {
        "ref": "MONDO:0005046",
        "name": "immune system disorder"
      },
      {
        "ref": "MONDO:0005570",
        "name": "hematologic disorder"
      }
    ],
    "definition": "A plasma cell neoplasm arising at an extraosseous site. There is no involvement of the bone marrow. It most frequently involves the oropharynx, nasopharynx, sinuses, and larynx. Other sites of involvement include the gastrointestinal tract, central nervous system, breast, skin, lymph nodes, and bladder. A minority of patients have a monoclonal gammopathy. Treatment includes radiation therapy. Progression to plasma cell myeloma occurs in a minority of patients."
  },
  "isLeaf": true,
  "isRoot": false,
  "child_count": 0,
  "parents": [
    {
      "id": 7255,
      "label": "plasmacytoma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6702
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:3721",
          "EFO:0006738",
          "GARD:0013446",
          "ICD9:238.6",
          "ICDO:9731/3",
          "MEDGEN:18506",
          "MESH:D010954",
          "MedDRA:10035484",
          "NCIT:C9349",
          "Orphanet:86855",
          "SCTID:415112005",
          "UMLS:C0032131",
          "icd11.foundation:1811140613"
        ],
        "synonyms": [
          "plasmacytoma",
          "solitary plasmacytoma",
          "anaplastic plasmacytoma",
          "anaplastic skeletal plasmacytoma (type)",
          "anaplastic solitary extramedullary plasmacytoma of the cecum (type)",
          "extramedullary anaplastic plasmacytoma (type)",
          "myeloma - solitary",
          "myeloma, solitary",
          "solitary myeloma"
        ],
        "categories": [
          {
            "ref": "MONDO:0005046",
            "name": "immune system disorder"
          },
          {
            "ref": "MONDO:0005570",
            "name": "hematologic disorder"
          }
        ],
        "definition": "Plasmacytoma is a localized mass of neoplastic monoclonal plasma cells that represents approximately 5% of all plasma cell neoplasms. There are two separate entities: primary plasmacytoma of the bone and extramedullary plasmacytoma of the soft tissues. Of the extramedullary plasmacytomas, 80% occur in the head and neck, usually in the upper respiratory tract. The median age at diagnosis is 50 years and the male to female ratio is 3:1. Long-term survival is possible following local radiotherapy, particularly for soft tissue presentations."
      },
      "child_count": 5,
      "reference_id": "MONDO:0005615"
    }
  ],
  "children": [],
  "roots": [
    {
      "id": 7255,
      "label": "plasmacytoma"
    }
  ]
}