{
  "id": 4793,
  "label": "bladder verrucous carcinoma",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0002759",
  "properties": {
    "xrefs": [
      "DOID:3741",
      "MEDGEN:267376",
      "NCIT:C39832",
      "UMLS:C1511208"
    ],
    "synonyms": [
      "bladder verrucous carcinoma",
      "bladder verrucous squamous cell carcinoma",
      "urinary bladder verrucous carcinoma"
    ],
    "categories": [
      {
        "ref": "MONDO:0002118",
        "name": "urinary system disorder"
      }
    ],
    "definition": "A verrucous carcinoma that involves the urinary bladder."
  },
  "isLeaf": true,
  "isRoot": false,
  "child_count": 0,
  "parents": [
    {
      "id": 4794,
      "label": "bladder squamous cell carcinoma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6727,
        6823
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:3742",
          "EFO:1000130",
          "MEDGEN:124645",
          "NCIT:C4031",
          "ONCOTREE:BLSC",
          "SCTID:255111004",
          "UMLS:C0279681"
        ],
        "synonyms": [
          "bladder epidermoid carcinoma",
          "bladder squamous cell cancer",
          "bladder squamous cell carcinoma",
          "epidermoid carcinoma of bladder",
          "epidermoid carcinoma of the bladder",
          "epidermoid carcinoma of the urinary bladder",
          "epidermoid carcinoma of urinary bladder",
          "squamous cell carcinoma of bladder",
          "squamous cell carcinoma of the bladder",
          "squamous cell carcinoma of the urinary bladder",
          "squamous cell carcinoma of urinary bladder",
          "urinary bladder epidermoid carcinoma",
          "urinary bladder squamous cell carcinoma",
          "BLSC"
        ],
        "categories": [
          {
            "ref": "MONDO:0002118",
            "name": "urinary system disorder"
          }
        ],
        "definition": "A squamous cell carcinoma of the bladder arising from metaplastic epithelium. It represents less than 10% of bladder carcinomas. The exception is the Middle East along the Nile Valley, where it represents the most common form of carcinoma because of the endemic nature of schistosomiasis. Bladder squamous cell carcinoma is often associated with long-standing chronic inflammation of the bladder and usually has a poor prognosis. The diagnosis of squamous cell carcinoma of the bladder should be reserved for those tumors that are predominantly keratin forming."
      },
      "child_count": 4,
      "reference_id": "MONDO:0002760"
    },
    {
      "id": 7597,
      "label": "verrucous carcinoma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        4983
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:3737",
          "EFO:0007535",
          "ICD9:199.1",
          "ICDO:8051/3",
          "MEDGEN:60213",
          "MESH:D018289",
          "NCIT:C3781",
          "SCTID:403904009",
          "UMLS:C0206706"
        ],
        "synonyms": [
          "verrucous carcinoma",
          "verrucous carcinoma NOS (morphologic abnormality)",
          "verrucous epidermoid carcinoma",
          "verrucous epidermoid cell carcinoma",
          "verrucous squamous carcinoma",
          "verrucous squamous cell carcinoma",
          "warty carcinoma"
        ],
        "definition": "A well differentiated squamous cell carcinoma characterized by a papillary growth pattern, acanthosis, mild cytologic atypia, and pushing tumor margins. The most commonly affected anatomic sites are the oral cavity, nasal cavity, larynx, esophagus, anus, vagina, vulva, and the plantar region of the foot."
      },
      "child_count": 10,
      "reference_id": "MONDO:0006006"
    }
  ],
  "children": [],
  "roots": [
    {
      "id": 4794,
      "label": "bladder squamous cell carcinoma"
    },
    {
      "id": 7597,
      "label": "verrucous carcinoma"
    }
  ]
}