{
  "id": 4796,
  "label": "esophagus verrucous carcinoma",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0002762",
  "properties": {
    "xrefs": [
      "DOID:3747",
      "GARD:0023238",
      "MEDGEN:272594",
      "NCIT:C27420",
      "UMLS:C1333470"
    ],
    "synonyms": [
      "esophageal verrucous cancer",
      "esophageal verrucous carcinoma",
      "esophagus verrucous carcinoma",
      "verrucous carcinoma of esophagus",
      "verrucous carcinoma of the esophagus",
      "verrucous carcinoma of the oesophagus"
    ],
    "categories": [
      {
        "ref": "MONDO:0004335",
        "name": "digestive system disorder"
      }
    ],
    "definition": "A rare variant of esophageal squamous cell carcinoma. It is an exophytic, cauliflower-like or papillary mass that can arise in any part of the esophagus. This variant of squamous cell carcinoma grows slowly and invades locally, with a very low metastasizing potential. (WHO)"
  },
  "isLeaf": true,
  "isRoot": false,
  "child_count": 0,
  "parents": [
    {
      "id": 7225,
      "label": "esophageal squamous cell carcinoma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6823,
        18977
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:3748",
          "EFO:0005922",
          "GARD:0018901",
          "MEDGEN:124635",
          "MESH:C562729",
          "MESH:D000077277",
          "NCIT:C4024",
          "ONCOTREE:ESCC",
          "Orphanet:99977",
          "SCTID:276804009",
          "UMLS:C0279626",
          "icd11.foundation:1417891145"
        ],
        "synonyms": [
          "ESCC",
          "esophageal epidermoid carcinoma",
          "esophageal scc",
          "esophageal squamous cell cancer",
          "esophageal squamous cell carcinoma",
          "esophagus scc",
          "esophagus squamous cell carcinoma",
          "oesophagus scc",
          "scc of esophagus",
          "scc of the esophagus",
          "scc of the oesophagus",
          "squamous cell car. - esophagus",
          "squamous cell car. - oesophagus",
          "squamous cell carcinoma of esophagus",
          "squamous cell carcinoma of oesophagus",
          "squamous cell carcinoma of the esophagus",
          "squamous cell carcinoma of the oesophagus"
        ],
        "categories": [
          {
            "ref": "MONDO:0004335",
            "name": "digestive system disorder"
          }
        ],
        "definition": "Esophageal squamous cell carcinoma (ESCC) is a type of esophageal carcinoma (EC) that can affect any part of the esophagus, but is usually located in the upper or middle third."
      },
      "child_count": 8,
      "reference_id": "MONDO:0005580"
    },
    {
      "id": 7597,
      "label": "verrucous carcinoma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        4983
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:3737",
          "EFO:0007535",
          "ICD9:199.1",
          "ICDO:8051/3",
          "MEDGEN:60213",
          "MESH:D018289",
          "NCIT:C3781",
          "SCTID:403904009",
          "UMLS:C0206706"
        ],
        "synonyms": [
          "verrucous carcinoma",
          "verrucous carcinoma NOS (morphologic abnormality)",
          "verrucous epidermoid carcinoma",
          "verrucous epidermoid cell carcinoma",
          "verrucous squamous carcinoma",
          "verrucous squamous cell carcinoma",
          "warty carcinoma"
        ],
        "definition": "A well differentiated squamous cell carcinoma characterized by a papillary growth pattern, acanthosis, mild cytologic atypia, and pushing tumor margins. The most commonly affected anatomic sites are the oral cavity, nasal cavity, larynx, esophagus, anus, vagina, vulva, and the plantar region of the foot."
      },
      "child_count": 10,
      "reference_id": "MONDO:0006006"
    }
  ],
  "children": [],
  "roots": [
    {
      "id": 7225,
      "label": "esophageal squamous cell carcinoma"
    },
    {
      "id": 7597,
      "label": "verrucous carcinoma"
    }
  ]
}