{
  "id": 4850,
  "label": "endometrial transitional cell carcinoma",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0002832",
  "properties": {
    "xrefs": [
      "DOID:4005",
      "GARD:0023259",
      "MEDGEN:273232",
      "NCIT:C40154",
      "UMLS:C1516864"
    ],
    "synonyms": [
      "endometrial transitional cell carcinoma"
    ],
    "categories": [
      {
        "ref": "MONDO:0005039",
        "name": "reproductive system disorder"
      }
    ],
    "definition": "A rare primary carcinoma of the endometrium characterized by the presence of malignant epithelial cells resembling urothelial transitional cells. The malignant transitional cells constitute at least 90% of the tumor cells."
  },
  "isLeaf": true,
  "isRoot": false,
  "child_count": 0,
  "parents": [
    {
      "id": 4530,
      "label": "endometrial carcinoma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6929,
        13033
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:2871",
          "EFO:1001512",
          "HP:0012114",
          "MEDGEN:96903",
          "NCIT:C7558",
          "ONCOTREE:UCEC",
          "SCTID:254878006",
          "UMLS:C0476089",
          "icd11.foundation:1123821211"
        ],
        "synonyms": [
          "endometrial cancer",
          "carcinoma of endometrium",
          "carcinoma of the endometrium",
          "carcinoma, endometrial, malignant",
          "endometrial carcinoma",
          "endometrial carcinoma (disease)",
          "endometrium carcinoma"
        ],
        "categories": [
          {
            "ref": "MONDO:0005039",
            "name": "reproductive system disorder"
          }
        ],
        "definition": "A malignant tumor arising from the epithelium that lines the cavity of the uterine body. The vast majority of endometrial carcinomas are adenocarcinomas; squamous cell and adenosquamous carcinomas represent a minority of the cases. Endometrioid adenocarcinoma is the most frequently seen variant of endometrial adenocarcinoma. Uterine bleeding is an initial clinical sign. The prognosis depends on the stage of the tumor, the depth of myometrial wall invasion, and the degree of differentiation."
      },
      "child_count": 14,
      "reference_id": "MONDO:0002447"
    },
    {
      "id": 7972,
      "label": "transitional cell carcinoma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6734
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:2671",
          "EFO:1000601",
          "GARD:0007794",
          "ICDO:8120/3",
          "MEDGEN:2875",
          "MESH:D002295",
          "NCIT:C2930",
          "UMLS:C0007138"
        ],
        "synonyms": [
          "transitional cell neoplasm",
          "transitional cell tumor",
          "transitional cell tumour",
          "carcinoma of transitional epithelial cell",
          "carcinoma of urothelial cell",
          "carcinoma, urothelial, malignant",
          "transitional carcinoma",
          "transitional cell carcinoma",
          "transitional epithelial cell carcinoma",
          "urothelial cell carcinoma"
        ],
        "definition": "A malignant neoplasm arising from the transitional epithelium, usually affecting the urinary bladder, ureter, or renal pelvis. It may or may not have a papillary configuration. It is graded 1 to 3 or 4 according to the degree of cellular differentiation and architectural patterns. Grade 1 transitional cell carcinoma is histologically benign but it may recur. Transitional cell carcinomas may also affect the upper respiratory tract and the ovaries."
      },
      "child_count": 9,
      "reference_id": "MONDO:0006474"
    }
  ],
  "children": [],
  "roots": [
    {
      "id": 4530,
      "label": "endometrial carcinoma"
    },
    {
      "id": 7972,
      "label": "transitional cell carcinoma"
    }
  ]
}