{
  "id": 4854,
  "label": "sarcomatoid transitional cell carcinoma",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0002837",
  "properties": {
    "xrefs": [
      "DOID:4014",
      "GARD:0023263",
      "ICDO:8122/3",
      "MEDGEN:83120",
      "NCIT:C4120",
      "UMLS:C0334271"
    ],
    "synonyms": [
      "sarcomatoid transitional cell carcinoma",
      "transitional cell carcinoma, sarcomatoid",
      "transitional cell spindle cell carcinoma",
      "transitional spindle cell carcinoma"
    ],
    "definition": "A poorly differentiated transitional cell carcinoma characterized by the presence of malignant cells with spindle cell morphologic features."
  },
  "isLeaf": false,
  "isRoot": false,
  "child_count": 3,
  "parents": [
    {
      "id": 7925,
      "label": "sarcomatoid carcinoma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6734,
        20048,
        20076
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:4015",
          "EFO:1000520",
          "ICDO:8032/3",
          "ICDO:8033/3",
          "MEDGEN:60009",
          "NCIT:C27004",
          "UMLS:C0205697"
        ],
        "synonyms": [
          "carcinoma, spindle cell, malignant",
          "pseudosarcomatous carcinoma",
          "sarcomatoid carcinoma",
          "spindle cell carcinoma",
          "spindle cell carcinoma (morphologic abnormality)"
        ],
        "definition": "A malignant epithelial neoplasm characterized by the presence of spindle cells and anaplastic morphologic features. Giant cells and a sarcomatous component may also be present."
      },
      "child_count": 24,
      "reference_id": "MONDO:0006406"
    },
    {
      "id": 7972,
      "label": "transitional cell carcinoma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6734
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:2671",
          "EFO:1000601",
          "GARD:0007794",
          "ICDO:8120/3",
          "MEDGEN:2875",
          "MESH:D002295",
          "NCIT:C2930",
          "UMLS:C0007138"
        ],
        "synonyms": [
          "transitional cell neoplasm",
          "transitional cell tumor",
          "transitional cell tumour",
          "carcinoma of transitional epithelial cell",
          "carcinoma of urothelial cell",
          "carcinoma, urothelial, malignant",
          "transitional carcinoma",
          "transitional cell carcinoma",
          "transitional epithelial cell carcinoma",
          "urothelial cell carcinoma"
        ],
        "definition": "A malignant neoplasm arising from the transitional epithelium, usually affecting the urinary bladder, ureter, or renal pelvis. It may or may not have a papillary configuration. It is graded 1 to 3 or 4 according to the degree of cellular differentiation and architectural patterns. Grade 1 transitional cell carcinoma is histologically benign but it may recur. Transitional cell carcinomas may also affect the upper respiratory tract and the ovaries."
      },
      "child_count": 9,
      "reference_id": "MONDO:0006474"
    }
  ],
  "children": [
    {
      "id": 5859,
      "label": "kidney pelvis sarcomatoid transitional cell carcinoma",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        4854,
        6936
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:6844",
          "GARD:0023773",
          "MEDGEN:233403",
          "NCIT:C6186",
          "UMLS:C1335752"
        ],
        "synonyms": [
          "infiltrating renal pelvis urothelial carcinoma, sarcomatoid variant",
          "kidney pelvis sarcomatoid transitional cell carcinoma",
          "renal pelvis sarcomatoid transitional cell carcinoma",
          "sarcomatoid transitional cell carcinoma of kidney pelvis",
          "sarcomatoid transitional cell carcinoma of renal pelvis",
          "sarcomatoid transitional cell carcinoma of the kidney pelvis",
          "sarcomatoid transitional cell carcinoma of the renal pelvis"
        ],
        "categories": [
          {
            "ref": "MONDO:0002118",
            "name": "urinary system disorder"
          }
        ],
        "definition": "An infiltrating transitional cell carcinoma that arises from the renal pelvis and exhibits sarcomatoid features."
      },
      "child_count": 0,
      "reference_id": "MONDO:0004009"
    },
    {
      "id": 6097,
      "label": "infiltrating bladder urothelial carcinoma sarcomatoid variant",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        4854,
        5752
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:7553",
          "EFO:1000303",
          "GARD:0023907",
          "MEDGEN:268929",
          "NCIT:C39824",
          "ONCOTREE:SCB",
          "UMLS:C1512743"
        ],
        "synonyms": [
          "sarcomatoid carcinoma of the urinary bladder",
          "infiltrating bladder urothelial carcinoma sarcomatoid variant",
          "infiltrating bladder urothelial carcinoma, sarcomatoid variant with heterologous elements",
          "infiltrating bladder urothelial carcinoma, sarcomatoid variant without heterologous elements"
        ],
        "categories": [
          {
            "ref": "MONDO:0002118",
            "name": "urinary system disorder"
          }
        ],
        "definition": "An invasive transitional cell carcinoma of the bladder that exhibits spindle cell sarcomatoid features."
      },
      "child_count": 0,
      "reference_id": "MONDO:0004278"
    },
    {
      "id": 25209,
      "label": "bladder sarcomatoid transitional cell carcinoma",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        4854,
        7252
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0080901",
          "GARD:0026608"
        ],
        "categories": [
          {
            "ref": "MONDO:0002118",
            "name": "urinary system disorder"
          }
        ],
        "definition": "A sarcomatoid transitional cell carcinoma that is located in the bladder."
      },
      "child_count": 0,
      "reference_id": "MONDO:0850347"
    }
  ],
  "roots": [
    {
      "id": 7925,
      "label": "sarcomatoid carcinoma"
    },
    {
      "id": 7972,
      "label": "transitional cell carcinoma"
    }
  ]
}