{
  "id": 4866,
  "label": "mediastinum sarcoma",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0002852",
  "properties": {
    "xrefs": [
      "DOID:4050",
      "GARD:0023270",
      "MEDGEN:233687",
      "NCIT:C6606",
      "UMLS:C1334678"
    ],
    "synonyms": [
      "mediastinal sarcoma",
      "mediastinum sarcoma",
      "sarcoma of mediastinum",
      "sarcoma of the mediastinum"
    ],
    "definition": "A rare sarcoma that arises from the mediastinum. Examples include liposarcoma, leiomyosarcoma, and angiosarcoma."
  },
  "isLeaf": false,
  "isRoot": false,
  "child_count": 7,
  "parents": [
    {
      "id": 18239,
      "label": "soft tissue sarcoma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6816,
        21548
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0070663",
          "EFO:1001968",
          "GARD:0004898",
          "MEDGEN:1642116",
          "NCIT:C9306",
          "NORD:1953",
          "Orphanet:3394",
          "SCTID:424952003",
          "UMLS:C4551687"
        ],
        "synonyms": [
          "malignant soft tissue tumor",
          "malignant soft tissue tumour",
          "connective tissue sarcoma",
          "malignant mesenchymal tumor",
          "malignant mesenchymal tumour",
          "non-Rhabdo. soft tissue sarcoma",
          "sarcoma of soft tissue",
          "sarcoma of the soft tissue",
          "soft part sarcoma",
          "soft tissue sarcoma"
        ],
        "definition": "A malignant neoplasm arising from muscle tissue, adipose tissue, blood vessels, fibrous tissue, or other supportive tissues excluding the bones."
      },
      "child_count": 92,
      "reference_id": "MONDO:0018078"
    },
    {
      "id": 22973,
      "label": "mediastinal soft tissue cancer",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        5425,
        7455,
        21548
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0027957",
          "MEDGEN:277335",
          "NCIT:C6642",
          "UMLS:C1334599"
        ],
        "synonyms": [
          "malignant mediastinal mesenchymal tumor",
          "malignant mediastinal mesenchymal tumour",
          "malignant mediastinal soft tissue neoplasm",
          "malignant mediastinal soft tissue tumor",
          "malignant mediastinal soft tissue tumour",
          "malignant soft tissue neoplasm of mediastinum",
          "malignant soft tissue neoplasm of the mediastinum",
          "malignant soft tissue tumor of mediastinum",
          "malignant soft tissue tumor of the mediastinum",
          "malignant soft tissue tumour of mediastinum",
          "malignant soft tissue tumour of the mediastinum",
          "mediastinal mesenchymal tumor, malignant"
        ],
        "definition": "A malignant neoplasm that arises from the soft tissues of the mediastinum."
      },
      "child_count": 3,
      "reference_id": "MONDO:0037743"
    }
  ],
  "children": [
    {
      "id": 4865,
      "label": "mediastinum rhabdomyosarcoma",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        4866,
        6928
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:4049",
          "GARD:0023269",
          "MEDGEN:233686",
          "NCIT:C6617",
          "UMLS:C1334677"
        ],
        "synonyms": [
          "mediastinal rhabdomyosarcoma",
          "mediastinum rhabdomyosarcoma (disease)",
          "rhabdomyosarcoma (disease) of mediastinum",
          "rhabdomyosarcoma of mediastinum",
          "rhabdomyosarcoma of the mediastinum"
        ],
        "definition": "A malignant mesenchymal tumor with skeletal muscle differentiation affecting the mediastinum."
      },
      "child_count": 0,
      "reference_id": "MONDO:0002851"
    },
    {
      "id": 5027,
      "label": "mediastinum angiosarcoma",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        4866,
        17394
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:4525",
          "GARD:0023340",
          "MEDGEN:233676",
          "NCIT:C6613",
          "UMLS:C1334649"
        ],
        "synonyms": [
          "angiosarcoma (disease) of mediastinum",
          "angiosarcoma of mediastinum",
          "angiosarcoma of the mediastinum",
          "hemangiosarcoma of mediastinum",
          "hemangiosarcoma of the mediastinum",
          "mediastinal angiosarcoma",
          "mediastinal hemangiosarcoma",
          "mediastinum angiosarcoma (disease)"
        ],
        "categories": [
          {
            "ref": "MONDO:0004995",
            "name": "cardiovascular disorder"
          }
        ],
        "definition": "A malignant vascular neoplasm arising from the mediastinum."
      },
      "child_count": 0,
      "reference_id": "MONDO:0003034"
    },
    {
      "id": 5310,
      "label": "mediastinum leiomyosarcoma",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        4866,
        6788
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:5292",
          "GARD:0023488",
          "MEDGEN:235310",
          "NCIT:C6619",
          "UMLS:C1334660"
        ],
        "synonyms": [
          "leiomyosarcoma of mediastinum",
          "leiomyosarcoma of the mediastinum",
          "mediastinal leiomyosarcoma",
          "mediastinum leiomyosarcoma"
        ],
        "categories": [
          {
            "ref": "MONDO:0002081",
            "name": "musculoskeletal system disorder"
          }
        ],
        "definition": "An aggressive malignant smooth muscle neoplasm, arising from the mediastinum. It is characterized by a proliferation of neoplastic spindle cells."
      },
      "child_count": 0,
      "reference_id": "MONDO:0003376"
    },
    {
      "id": 5389,
      "label": "mediastinum synovial sarcoma",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        4866,
        11594
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:5488",
          "GARD:0023514",
          "MEDGEN:233174",
          "NCIT:C6618",
          "UMLS:C1334681"
        ],
        "synonyms": [
          "mediastinal synovial sarcoma",
          "mediastinum synovial sarcoma (disease)",
          "synovial sarcoma of mediastinum",
          "synovial sarcoma of the mediastinum"
        ],
        "definition": "A synovial sarcoma arising from the mediastinum."
      },
      "child_count": 0,
      "reference_id": "MONDO:0003467"
    },
    {
      "id": 5495,
      "label": "mediastinum liposarcoma",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        4866,
        6790
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:5713",
          "GARD:0023584",
          "MEDGEN:233683",
          "NCIT:C6614",
          "UMLS:C1334663"
        ],
        "synonyms": [
          "lip mediastinum sarcoma",
          "liposarcoma of mediastinum",
          "liposarcoma of the mediastinum",
          "mediastinal liposarcoma",
          "mediastinum liposarcoma"
        ],
        "categories": [
          {
            "ref": "MONDO:0003900",
            "name": "connective tissue disorder"
          }
        ],
        "definition": "A malignant adipose tissue neoplasm of the anterior, middle or posterior mediastinum."
      },
      "child_count": 0,
      "reference_id": "MONDO:0003601"
    },
    {
      "id": 5681,
      "label": "mediastinal extraskeletal osteosarcoma",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        4672,
        4866
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:6208",
          "GARD:0023678",
          "MEDGEN:235314",
          "NCIT:C6615",
          "UMLS:C1334675"
        ],
        "synonyms": [
          "mediastinal extraskeletal osteosarcoma",
          "mediastinal osteogenic sarcoma",
          "mediastinal osteosarcoma",
          "mediastinum osteosarcoma (disease)",
          "osteogenic sarcoma of mediastinum",
          "osteogenic sarcoma of the mediastinum",
          "osteosarcoma of mediastinum",
          "osteosarcoma of the mediastinum"
        ],
        "definition": "An osteosarcoma arising from the mediastinum."
      },
      "child_count": 0,
      "reference_id": "MONDO:0003808"
    },
    {
      "id": 5932,
      "label": "malignant melanocytic peripheral nerve sheath tumor of mediastinum",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        4866,
        5728
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:7077",
          "GARD:0023819",
          "MEDGEN:233154",
          "NCIT:C6630",
          "UMLS:C1334600"
        ],
        "synonyms": [
          "malignant mediastinal melanocytic peripheral nerve sheath tumor",
          "malignant mediastinal melanocytic peripheral nerve sheath tumour",
          "malignant melanocytic neoplasm of the peripheral nerve sheath of mediastinum",
          "malignant melanocytic peripheral nerve sheath tumor of mediastinum",
          "malignant melanotic peripheral nerve sheath tumor of the mediastinum",
          "malignant melanotic peripheral nerve sheath tumour of the mediastinum",
          "mediastinal melanocytic MPNST",
          "mediastinum malignant melanocytic neoplasm of the peripheral nerve sheath"
        ],
        "categories": [
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "A rare variant of malignant peripheral nerve sheath tumor that arises from the mediastinum. It is characterized by the presence of malignant cells that contain melanin."
      },
      "child_count": 0,
      "reference_id": "MONDO:0004098"
    }
  ],
  "roots": [
    {
      "id": 18239,
      "label": "soft tissue sarcoma"
    },
    {
      "id": 22973,
      "label": "mediastinal soft tissue cancer"
    }
  ]
}