{
  "id": 4877,
  "label": "rhabdomyosarcoma with mixed embryonal and alveolar features",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0002863",
  "properties": {
    "xrefs": [
      "DOID:4065",
      "GARD:0023280",
      "ICDO:8902/3",
      "MEDGEN:313444",
      "NCIT:C4259",
      "UMLS:C1709053"
    ],
    "synonyms": [
      "mixed alveolar rhabdomyosarcoma",
      "mixed type alveolar rhabdomyosarcoma",
      "rhabdomyosarcoma with mixed embryonal and alveolar features"
    ],
    "definition": "A rhabdomyosarcoma composed of embryonic and alveolar components. It is characterized by the presence of spindle cells with myoblastic differentiation, a myxoid stroma, and fibrous septa. These tumors were previously considered variants of alveolar rhabdomyosarcoma. The lack of PAX3-FOXO1 fusions in most of these tumors suggests that are biologically and clinically related to embryonal rhabdomyosarcoma."
  },
  "isLeaf": true,
  "isRoot": false,
  "child_count": 0,
  "parents": [
    {
      "id": 6928,
      "label": "rhabdomyosarcoma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        18239
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:3247",
          "EFO:0002918",
          "GARD:0011951",
          "HP:0002859",
          "ICD9:171.9",
          "ICDO:8900/3",
          "MEDGEN:20561",
          "MESH:D012208",
          "MedDRA:10039022",
          "NANDO:2200056",
          "NCIT:C3359",
          "ONCOTREE:RMS",
          "Orphanet:780",
          "SCTID:302847003",
          "UMLS:C0035412"
        ],
        "synonyms": [
          "rhabdomyosarcoma",
          "rhabdomyosarcoma (disease)",
          "rhabdomyosarcoma, malignant"
        ],
        "definition": "A rare aggressive malignant mesenchymal neoplasm arising from skeletal muscle. It usually occurs in children and young adults. Only a small percentage of tumors arise in the skeletal muscle of the extremities. The majority arise in other anatomical sites."
      },
      "child_count": 20,
      "reference_id": "MONDO:0005212"
    }
  ],
  "children": [],
  "roots": [
    {
      "id": 6928,
      "label": "rhabdomyosarcoma"
    }
  ]
}