{
  "id": 4895,
  "label": "colon neuroendocrine neoplasm",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0002882",
  "properties": {
    "xrefs": [
      "DOID:4118",
      "GARD:0019755",
      "MEDGEN:234162",
      "NCIT:C5697",
      "Orphanet:100080",
      "UMLS:C1333097",
      "icd11.foundation:144503516"
    ],
    "synonyms": [
      "colon NET",
      "colon neuroendocrine neoplasm",
      "colon neuroendocrine tumor",
      "colon neuroendocrine tumor, well differentiated, low or intermediate grade",
      "colon neuroendocrine tumour",
      "colonic neuroendocrine neoplasm",
      "colonic neuroendocrine tumour",
      "neuroendocrine neoplasm of colon",
      "neuroendocrine neoplasm of the colon",
      "neuroendocrine tumor of the colon",
      "neuroendocrine tumour of the colon"
    ],
    "categories": [
      {
        "ref": "MONDO:0004335",
        "name": "digestive system disorder"
      },
      {
        "ref": "MONDO:0005151",
        "name": "endocrine system disorder"
      }
    ],
    "definition": "A neoplasm with neuroendocrine differentiation that arises from the colon. It includes well differentiated neuroendocrine tumors (low and intermediate grade) and poorly differentiated neuroendocrine carcinomas (high grade)."
  },
  "isLeaf": false,
  "isRoot": false,
  "child_count": 3,
  "parents": [
    {
      "id": 4896,
      "label": "intestinal neuroendocrine neoplasm",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        20357,
        21456
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:4119",
          "GARD:0023287",
          "MEDGEN:233567",
          "NCIT:C5695",
          "UMLS:C1334231"
        ],
        "synonyms": [
          "intestinal neuroendocrine neoplasm",
          "intestine NET",
          "intestine neuroendocrine neoplasm",
          "intestine neuroendocrine tumor",
          "intestine neuroendocrine tumor, well differentiated, low or intermediate grade",
          "intestine neuroendocrine tumour",
          "neuroendocrine neoplasm of intestine",
          "neuroendocrine neoplasm of the intestine",
          "intestinal neuroendocrine benign tumor",
          "intestinal neuroendocrine benign tumour"
        ],
        "categories": [
          {
            "ref": "MONDO:0004335",
            "name": "digestive system disorder"
          },
          {
            "ref": "MONDO:0005151",
            "name": "endocrine system disorder"
          }
        ],
        "definition": "A neoplasm with neuroendocrine differentiation that arises from the small or large intestine. It includes well differentiated neuroendocrine tumors (low and intermediate grade) and poorly differentiated neuroendocrine carcinomas (high grade)."
      },
      "child_count": 8,
      "reference_id": "MONDO:0002883"
    },
    {
      "id": 7078,
      "label": "colonic neoplasm",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        5340,
        7022
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "EFO:0004288",
          "MEDGEN:3165",
          "MESH:D003110",
          "NCIT:C2953",
          "UMLS:C0009375"
        ],
        "synonyms": [
          "colon neoplasm",
          "colon neoplasm (disease)",
          "colon tumor",
          "colon tumour",
          "colonic neoplasm",
          "colonic tumor",
          "colonic tumour",
          "neoplasm of colon",
          "neoplasm of the colon",
          "tumor of colon",
          "tumor of the colon",
          "tumour of colon",
          "tumour of the colon"
        ],
        "categories": [
          {
            "ref": "MONDO:0004335",
            "name": "digestive system disorder"
          }
        ],
        "definition": "A benign or malignant neoplasm that affects the colon. Representative examples of benign neoplasms include lipoma and leiomyoma. Representative examples of malignant neoplasms include carcinoma, lymphoma, and sarcoma. Colonic adenomas always exhibit epithelial dysplasia and are considered premalignant neoplasms."
      },
      "child_count": 16,
      "reference_id": "MONDO:0005401"
    }
  ],
  "children": [
    {
      "id": 5833,
      "label": "colon small cell neuroendocrine carcinoma",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        2894,
        4179,
        4895
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:6727",
          "GARD:0023759",
          "MEDGEN:232087",
          "NCIT:C6761",
          "UMLS:C1333099"
        ],
        "synonyms": [
          "Oat cell carcinoma of colon",
          "Oat cell carcinoma of the colon",
          "Oat cell colon carcinoma",
          "colon Oat cell carcinoma",
          "colon small cell carcinoma",
          "colon small cell neuroendocrine cancer",
          "colon small cell neuroendocrine carcinoma",
          "colonic Oat cell carcinoma",
          "colonic small cell carcinoma",
          "small cell carcinoma of colon",
          "small cell carcinoma of the colon",
          "small cell colon carcinoma"
        ],
        "categories": [
          {
            "ref": "MONDO:0004335",
            "name": "digestive system disorder"
          },
          {
            "ref": "MONDO:0005151",
            "name": "endocrine system disorder"
          }
        ],
        "definition": "An aggressive, high-grade, and poorly differentiated carcinoma with neuroendocrine differentiation that arises from the colon. It is characterized by the presence of malignant small cells."
      },
      "child_count": 0,
      "reference_id": "MONDO:0003978"
    },
    {
      "id": 16041,
      "label": "neuroendocrine tumor of the colon, well differentiated, low or intermediate grade tumor",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        2885,
        4895,
        21434
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0025057",
          "MEDGEN:1617490",
          "NCIT:C135212",
          "UMLS:C4525742"
        ],
        "synonyms": [
          "carcinoid tumor of colon",
          "carcinoid tumour of colon",
          "colon neuroendocrine tumor",
          "colon neuroendocrine tumour",
          "neuroendocrine neoplasm of the colon",
          "NET of the colon",
          "colonic NET"
        ],
        "categories": [
          {
            "ref": "MONDO:0004335",
            "name": "digestive system disorder"
          },
          {
            "ref": "MONDO:0005151",
            "name": "endocrine system disorder"
          }
        ],
        "definition": "A well differentiated, low or intermediate grade tumor with neuroendocrine differentiation that arises from the colon."
      },
      "child_count": 9,
      "reference_id": "MONDO:0015067"
    },
    {
      "id": 21454,
      "label": "appendix neuroendocrine neoplasm",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        3476,
        4895
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0025404",
          "MEDGEN:361887",
          "NCIT:C60709",
          "UMLS:C1879718"
        ],
        "synonyms": [
          "appendix neuroendocrine neoplasm",
          "neuroendocrine neoplasm of vermiform appendix",
          "vermiform appendix NET",
          "vermiform appendix neuroendocrine neoplasm",
          "vermiform appendix neuroendocrine tumor",
          "vermiform appendix neuroendocrine tumor, well differentiated, low or intermediate grade",
          "vermiform appendix neuroendocrine tumour"
        ],
        "categories": [
          {
            "ref": "MONDO:0004335",
            "name": "digestive system disorder"
          },
          {
            "ref": "MONDO:0005151",
            "name": "endocrine system disorder"
          }
        ],
        "definition": "A neoplasm with neuroendocrine differentiation that arises from the appendix. It includes well differentiated neuroendocrine tumors (low and intermediate grade) and poorly differentiated neuroendocrine carcinomas (high grade)."
      },
      "child_count": 2,
      "reference_id": "MONDO:0024501"
    }
  ],
  "roots": [
    {
      "id": 4896,
      "label": "intestinal neuroendocrine neoplasm"
    },
    {
      "id": 7078,
      "label": "colonic neoplasm"
    }
  ]
}